Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerus

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 3, 2000, Pages 720-726

  Jensen, Susan E ^a   Elder, Kenneth J ^a   Aidoo, Kwamena A ^a   Paradkar, Ashish S ^a,b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b DIVERSA CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLAVULANIC ACID;

ARTICLE; CATALYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ANALYSIS; GENE CLUSTER; GENE ISOLATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; STREPTOMYCES CLAVULIGERUS;

BIOLOGICAL ASSAY; BLOTTING, SOUTHERN; CEPHAMYCINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLAVULANIC ACID; GENE DELETION; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OPEN READING FRAMES; PLASMIDS; SEQUENCE ANALYSIS, DNA; STREPTOMYCES;

EID: 0034004958     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.3.720-726.2000     Document Type: Article

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