The E3 ubiquitin ligase WWP1 selectively targets HER4 and its proteolytically derived signaling isoforms for degradation

Molecular and Cellular Biology

Volumn 29, Issue 3, 2009, Pages 892-906

  Feng, Shu Mang ^a   Muraoka Cook, Rebecca S ^a   Hunter, Debra ^a   Sandahl, Melissa A ^a   Caskey, Laura S ^a   Miyazawa, Keiji ^b   Atfi, Azeddine ^c   Earp III, H Shelton ^a,d  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c HÔPITAL SAINT ANTOINE   (France)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 4; EPIDERMAL GROWTH FACTOR RECEPTOR HER4; FOCAL ADHESION KINASE 2; ISOPROTEIN; ISOPROTEIN CYT1; ISOPROTEIN CYT2; MESSENGER RNA; PROTEASOME; PROTEIN TYROSINE KINASE; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE E3 WWP1; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG; EPIDERMAL GROWTH FACTOR RECEPTOR; UBIQUITIN PROTEIN LIGASE; WWP1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; UBIQUITINATION; ANIMAL; CELL FRACTIONATION; CELL MEMBRANE; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR WEIGHT; MOUSE; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SOLUBILITY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME STABILITY; GENE EXPRESSION REGULATION; HUMANS; MICE; MOLECULAR WEIGHT; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; SIGNAL TRANSDUCTION; SOLUBILITY; SUBCELLULAR FRACTIONS; SUBSTRATE SPECIFICITY; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 59249091294     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00595-08     Document Type: Article

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