Dietary antioxidants in inflammatory arthritis: Do they have any role in etiology or therapy?

Nature Clinical Practice Rheumatology

Volumn 4, Issue 11, 2008, Pages 590-596

  Pattison, Dorothy J ^a,b   Winyard, Paul G ^c  

^a ROYAL CORNWALL HOSPITALS NHS TRUST   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c PENINSULA MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BETA CAROTENE; BETA CRYPTOXANTHIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLACEBO; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RETINOL; RHEUMATOID FACTOR; SELENIUM; ZEAXANTHIN; ANTIOXIDANT;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; CLINICAL TRIAL; DIET SUPPLEMENTATION; DIETARY INTAKE; DNA DAMAGE; DRUG EFFICACY; DRUG STRUCTURE; FEEDING BEHAVIOR; HEALTH FOOD; HUMAN; IMMUNOPATHOGENESIS; LEUKOCYTE ACTIVATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; RISK FACTOR; SIGNAL TRANSDUCTION; VITAMIN BLOOD LEVEL; VITAMIN INTAKE; DIET; DIET THERAPY; METABOLISM;

ANTIOXIDANTS; ARTHRITIS, RHEUMATOID; DIET; DIETARY SUPPLEMENTS; HUMANS; OXIDATIVE STRESS;

EID: 59149095775     PISSN: 17458382     EISSN: 17458390     Source Type: Journal    
DOI: 10.1038/ncprheum0920     Document Type: Review

References (40)

1. Symmons DP et al. (1994) The incidence of rheumatoid arthritis in the United Kingdom: Results from the Norfolk Arthritis Register. Br J Rheumatol 33: 735-739
2. Karlson EW et al. (2008) Associations between human leukocyte antigen, PTPN22, CTLA4 genotypes and rheumatoid arthritis phenotypes of autoantibody status, age at diagnosis and erosions in a large cohort study. Ann Rheum Dis 67: 358-363
3. Symmons DPM et al. (2000) Early inflammatory polyarthritis: results from the Norfolk Arthritis Register with a review of the literature. I. Risk factors for the development of inflammatory polyarthritis and rheumatoid arthritis. Rheumatology (Oxford) 39: 835-843
4. Aho K and Heliövaara M (2004) Risk factors for rheumatoid arthritis. Ann Med 36: 242-251
5. Pattison DJ et al. (2004) Does diet have a role in the aetiology of rheumatoid arthritis? Proc Nutr Soc 63: 137-143
6. Arts IC and Hollman PC (2005) Polyphenols and disease risk in epidemiologic studies. Am J Clin Nutr 81 (Suppl 1): 317S-325S
7. Halliwell B and Gutteridge JMC (1999) Free Radicals in Biology and Medicine (edn 3) New York: Oxford University Press, USA
8. Sies H (1997) Preface. In Antioxidants in Disease Mechanisms and Therapy, xxiii (Eds Packer et al.) London: Academic Press
9. Winyard PG et al. (2005) Oxidative activation of antioxidant defence. Trends Biochem Sci 30: 453-461
10. Jones OTG and Hancock JT (2000) The NADPH oxidase of neutrophils and other cells. In Free Radicals and Inflammation, 21-46 (Eds Winyard PG et al. Basel: Birkhauser
11. Karunasinghe N et al. (2006) Hemolysate thioredoxin reductase and glutathione peroxidase activities correlate with serum selenium in a group of New Zealand men at high prostate cancer risk. J Nutr 136: 2232-2235
12. Rinehart JF et al. (1936) Reduced ascorbic acid content of blood plasma in rheumatoid arthritis. Proc Soc Exp Bol Med 35: 347-350
13. Fairburn K et al. (1992) Alpha-tocopherol, lipids and lipoproteins in knee-joint synovial fluid and serum from patients with inflammatory joint disease. Clin Sci (Lond) 83: 657-664
14. Lunec J and Blake DR (1985) The determination of dehydroascorbic acid and ascorbic acid in the serum and synovial fluid of patients with rheumatoid arthritis (RA). Free Radic Res Commun 1: 31-39
15. Canter PH et al. (2007) The antioxidant vitamins A, C, E and selenium in the treatment of arthritis: A systematic review of randomized clinical trials. Rheumatology (Oxford) 46: 1223-1233
16. Edmonds SE et al. (1997) Putative analgesic activity of repeated oral doses of vitamin E in the treatment of rheumatoid arthritis. Results of a prospective placebo controlled double blind trial. Ann Rheum Dis 56: 649-655
17. Winrow VR et al. (1993) Free radicals in inflammation: Second messengers and mediators of tissue destruction. Br Med Bull 49 506-522
18. Bjelakovic G et al. (2007) Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis. JAMA 297: 842-857
19. Willett WC et al. (1995) Mediterranean diet pyramid: A cultural model for healthy eating. Am J Clin Nutr 61 (Suppl 6): 1402S-1406S
20. Sköldstam L et al. (2003) An experimental study of a Mediterranean diet intervention for patients with rheumatoid arthritis. Ann Rheum Dis 62: 208-214
21. McKellar G et al. (2007) A pilot study of a Mediterranean-type diet intervention in female patients with rheumatoid arthritis living in areas of social deprivation in Glasgow. Ann Rheum Dis 66: 1239-1243
22. Pattison DJ et al. (2004) The role of diet in susceptibility to rheumatoid arthritis: A systematic review. J Rheumatol 31: 1310-1319
23. Linos A et al. (1999) Dietary factors in relation to rheumatoid arthritis: A role for olive oil and cooked vegetables? Am J Clin Nutr 70: 1077-1082
24. Pattison DJ et al. (2004) Vitamin C and the risk of developing inflammatory polyarthritis: A prospective nested case control study. Ann Rheum Dis 63: 843-847
25. Cerhan JR et al. (2003) Antioxidant micronutrients and risk of rheumatoid arthritis in a cohort of older women. Am J Epidemiol 157: 345-354
26. Pedersen M et al. (2005) Diet and risk of rheumatoid arthritis in a prospective cohort. J Rheumatol 32: 1249-1252
27. Shapiro JA et al. (1996) Diet and rheumatoid arthritis in women: A possible protective effect of fish consumption. Epidemiology 7 256-263
28. Pattison DJ et al. (2005) Dietary beta-cryptoxanthin and inflammatory polyarthritis: Results from a population-based prospective study. Am J Clin Nutr 82: 451-455
29. Heliövaara M et al. (1994) Serum antioxidants and risk of rheumatoid arthritis. Ann Rheum Dis 53: 51-53
30. Comstock GW et al. (1997) Serum concentrations of alpha-tocopherol, beta-carotene, and retinol preceding the diagnosis of rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 56: 323-325
31. Knekt P et al. (2000) Serum selenium, serum alpha-tocopherol, and the risk of rheumatoid arthritis. Epidemiology 11: 402-405
32. Bashir S et al. (1993) Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases. Ann Rheum Dis 52: 659-666
33. Tak PP (2000) Rheumatoid arthritis and p53: How oxidative stress might alter the course of inflammatory diseases. Immunol Today 21: 78-82
34. Eggleton P et al. (2008) Consequence of neo-antigenicity of the 'altered self'. Rheumatology (Oxford) 47: 567-571
35. Reddanna P et al. (1985) Inhibition of 5-lipoxygenase by vitamin E. FEBS Lett. 193: 39-43
36. 2. Biochim Biophys Acta 876: 639-645
37. Azzi A (2007) Molecular mechanism of alpha-tocopherol action. Free Radical Biol Med 43: 16-21
38. Stocker R and Keaney JF Jr (2004) Role of oxidative modifications in atherosclerosis. Physiol Rev 84: 1381-1478
39. Premkumar K and Bowlus CL (2004) Ascorbic acid does not increase the oxidative stress induced by dietary iron in C3H mice. J Nutr 134: 435-438
40. Hultqvist M et al. (2006) A new arthritis therapy with oxidative burst inducers. PLoS Med 3: E348