Diffusion- and perfusion-weighted MR imaging of transient focal cerebral ischaemia in mice

NMR in Biomedicine

Volumn 12, Issue 8, 1999, Pages 525-534

  Van Dorsten, Ferdi A ^a   Hata, Ryuji ^a   Maeda, Keiichiro ^a   Franke, Claudia ^a   Eis, Manfred ^b   Hossmann, Konstantin Alexander ^a   Hoehn, Mathias ^a  

^a MAX PLANCK INSTITUTE FOR NEUROLOGICAL RESEARCH   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Cerebral blood flow; Delayed neuronal damage; Ischemia; Mouse brain; Reperfusion; Transgenic mice

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN CORTEX; BRAIN PERFUSION; CONTROLLED STUDY; DIFFUSION COEFFICIENT; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PUTAMEN; TRANSGENIC MOUSE; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; CEREBROVASCULAR CIRCULATION; DIFFUSION; ISCHEMIC ATTACK, TRANSIENT; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED C57BL; REPERFUSION;

ANIMALIA; MUS MUSCULUS;

EID: 0033366955     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1492(199912)12:8<525::AID-NBM597>3.0.CO;2-F     Document Type: Article

References (49)

1. Siesjö, B. K. Pathophysiology and treatment of focal cerebral ischemia. I. Pathophysiology. J. Neurosurg. 77, 169-184 (1992)
2. Hallenbeck, J. M. and Dutka, A. J. Background review and current concepts of reperfusion injury. Arch. Neurol. 47, 1245-1254 (1990).
3. Chan, P. H. Role of oxidants in ischemic brain damage. Stroke 27, 1124-1129 (1996).
4. Huang, Z., Huang, P. L., Panahian, N., Dalkara, T., Fishman, M. C. and Moskowitz, M. A. Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 265, 1883-1885 (1994).
5. 2-weighted MRI and spectroscopy. Magn. Reson. Med. 14, 330-346 (1990).
6. 2-weighted and magnetic susceptibility-enhanced MR imaging in cats. Am. J. Neuroradiol. 11, 423-429 (1990).
7. Minematsu, K., Li, L. M., Sotak, C. H., Davis, M. A. and Fisher, M. Reversible focal ischemic-injury demonstrated by diffusion-weighted magnetic-resonance-imaging in rats. Stroke 23, 1304-1310 (1992).
8. 2-weighted MRI for the early detection of cerebral ischemia and reperfusion in rats. Magn. Reson. Med. 18, 39-50 (1991).
9. Williams, D. S., Detre, J. A., Leigh, J. S. and Koretsky, A. P. Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc. Natl, Acad. Sci. USA 89, 212-216 (1992).
10. Detre, J. A., Leigh, J. S., Williams, D. S. and Koretsky, A. P. Perfusion imaging. Magn. Reson. Med. 23, 37-45 (1992).
11. Jiang, Q., Zhang, Z. G., Chopp, M., Helpern, J. A., Ordidge, R. J., Garcia, J. H., Marchese, B. A., Qing, Z. X. and Knight, R. A. Temporal evolution and spatial distribution of the diffusion constant of water in rat brain after transient middle cerebral artery occlusion. J. Neural. Sci. 120, 123-130 (1993).
12. Zaharchuk, G., Hara, H., Huang, P. L., Fishman, M. C., Moskowitz, M. A., Jenkins, B. G. and Rosen, B. R. Neuronal nitric oxide synthase mutant mice show smaller infarcts and attenuated apparent diffusion coefficient changes in the peri-infarct zone during focal cerebral ischemia. Magn. Reson. Med. 37, 170-175 (1997).
13. Hata, R., Mies, G., Wiessner, C., Fritze, K., Hesselbarth, D., Brinker, G. and Hossmann, K.-A. A reproducible model of middle cerebral artery occlusion in mice: hemodynamic, biochemical and magnetic resonance imaging. J. Cerebr. Blood Flow Metab. 18, 367-375 (1998).
14. Hesselbarth, D., Franke, C., Hata, R., Brinker, G. and Hoehn-Berlage, M. High resolution MRI and MRS: a feasibility study for the investigation of focal cerebral ischemia in mice. NMR Biomed. 11, 423-429 (1998).
15. Hara, H., Huang, P. L., Panahian, N., Fishman, M. C. and Moskowitz, M. A. Reduced brain edema and infarct volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion. J. Cerebr. Blood Flow Metab. 16, 605-611 (1996).
16. Stejskal, E. O. and Tanner, J. E. Spin-diffusion measurements: spin-echoes in the presence of a time-dependent field gradient. J. Chem. Phys. 42, 288-292 (1965).
17. 2*-weighted MRI. NMR Biomed. 8, 20-23 (1996).
18. Eis, M. and Hoehn-Berlage, M. Correction of gradient crosstalk and optimization of measurement parameters in diffusion MR imaging. J. Magn. Reson. 107, 222-234 (1995).
19. Hoehn-Berlage, M., Morris, D. G., Kohno, K., Mies, G., Leibfritz, D. and Hossmann, K.-A. Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain - the relationship of quantitative diffusion NMR imaging to reduction in cerebral blood flow and metabolic disturbances. J. Cerebr. Blood Flow Metab. 15, 1002-1011 (1995).
20. Eis, M. and Allegrini, P. An image-oriented algorithm for improved analysis of two-compartment processes in quantitative relaxation and diffusion MRI. 4th Annual Meeting of the International Society of Magnetic Resonance in Medicine, Abstract, p. 1629 (1996).
21. Hoehn-Berlage, M., Eis, M. and Schmitz, B. Regional and directional anisotropy in rat brain. NMR Biomed. 12, 45-50 (1999).
22. Herscovitch, P. and Raichle, M. What is the correct value for the brain-blood partition coefficient for water? J. Cerebr. Blood Flow Metab. 5, 65-69 (1985).
23. Kogure, K. and Alonso, O. F. A pictorial representation of endogenous brain ATP by a bioluminescent method. Brain Res. 154, 273-284 (1978).
24. Paschen, W., Mies, G. and Hossmann, K.-A. Threshold relationship between cerebral blood flow, glucose utilization, and energy metabolites during development of stroke in gerbils. Exp. Neurol. 117, 325-333 (1992).
25. Hoehn-Berlage, M., Busch, E. and Eis, M. Determination of ADC-threshold for the discrimination of ischemic core during middle cerebral artery occlusion in rats. 5th Annual Meeting of the International Society of Magnetic Resonance in Medicine. Abstract, p. 598 (1997).
26. Zarow, G. J., Graham, S. H., Mintorovitch, J., Chen, J., Yang, G. and Weinstein, P. R. Diffusion-weighted magnetic resonance imaging during brief focal cerebral ischemia and early reperfusion: evolution of delayed infarction in rats. Neurol. Res. 17, 449-454 (1995).
27. Mancuso, A., Nimura, T. and Weinstein, P. R. Prediction of delayed ischemic injury with diffusion-weighted MRI following temporary middle cerebral artery occulusion in rats. Brain Res. 760, 42-51 (1997).
28. Aronowski, J., Strong, R. and Grotta, J. C. Reperfusion injury: demonstration of brain damage produced by reperfusion after transient focal ischemia in rats. J. Cerebr. Blood Flow Metab. 17, 1048-1056 (1997).
29. Memezawa, H., Smith, M.-L. and Siesjö, B. K. Penumbral tissue salvaged by reperfusion following middle cerebral artery occlusion in rats. Stroke 23, 552-559 (1992).
30. Hossmann, K.-A. Viability thresholds and the penumbra of focal ischemia. Ann. Neurol. 36, 557-565 (1994).
31. Busza, A. L., Allen, K. L., King, M. D., van Bruggen, N., Williams, S. R. and Gadian, D. G. Diffusion-weighted imaging studies of cerebral ischemia in gerbils - potential relevance to energy failure. Stroke 23, 1602-1612 (1992).
32. Dijkhuizen, R. M., Berkelbach van der Sprenkel, J. W., Tulleken, K. A. F. and Nicolay, K. Regional assessment of tissue oxygenation and the temporal evolution of hemodynamic parameters and water diffusion during acute focal ischemia in rat brain. Brain Res. 750, 161-170 (1997).
33. Miyabe, M., Mori, S., van Zijl, P. C. M., Kirsch, J. R., Eleff, S. M., Koehler, R. C. and Traystman, R. J. Correlation of the average water diffusion constant with cerebral blood flow and ischemic damage after transient middle cerebral artery occlusion in cats. J. Cerebr. Blood Flow Metab. 16, 881-891 (1996).
34. Hossmann, K.-A. and Hoehn-Berlage, M. Diffusion and perfusion MR imaging of cerebral ischemia. Cerebrovasc. Brain Metab. Rev. 7, 187-217 (1995).
35. Benveniste, H., Hedlund, L. W. and Johnson, G. A. Mechanism of detection of acute cerebral ischemia in rats by diffusion-weighted magnetic resonance microscopy. Stroke 23, 746-754 (1992).
36. van der Toorn, A., Sykova, E. D. R. M., Vorisek, I., Vargova, L., Skobisova, E., van Lookeren Campagne, M., Reese, T. and Nicolay, K. Dynamic changes in water ADC, energy metabolism, extracellular space volume, and tortuosity in neonatal rat brain during global ischemia. Magn. Reson. Med. 36, 52-60 (1996).
37. 2 relaxation of experimental brain tumors in the cat: a multiparameter tissue characterization. Magn. Reson. Imag. 10, 935-947 (1992).
38. Brant-Zawadzki, M., Pereira, B., Weinstein, P., Moore, S., Kucharzyk, W., Berry, I., McNamara, M. and Derugin, N. MR imaging of acute experimental ischemia in cats. Am. J. Neuroradiol. 7, 7-11 (1986).
39. Kato, H., Kogure, K., Ohtomo, H., Izumiyama, M., Tobita, M., Masui. S., Yamamot, E., Kohno, H., Ikebe, I. and Watanabe, T. Characterization of experimental brain edema utilizing proton nuclear magnetic resonance imaging. J. Cerebr. Blood Flow Metab. 6, 212-221 (1986).
40. 1H magnetic resonance spectroscopy in rats. Neurosurgery 38, 121-129 (1996).
41. Belayev, L., Zhao, W., Busto, R. and Ginsberg, M. D. Transient middle cerebral artery occlusion by intraluminal suture: I. Three-dimensional autoradiographic image-analysis of local cerebral glucose metabolism - blood flow interrelationships during ischemia and early recirculation. J. Cerebr. Blood Flow Metab. 17, 1266-1280 (1997).
42. Tsuchidate, R., He, Q.-P., Smith, M.-L. and Siesjö, B. K. Regional cerebral blood flow during and after 2 hours of middle cerebral artery occlusion. J. Cerebr. Blood Flow Metab. 17, 1066-1073 (1997).
43. 14C]iodoantipyrine autoradiographic study. Brain Res. 691, 160-168 (1995).
44. Tatlisumak, T., Carano, R. A. D., Takano, K., Opgenorth, T. J., Sotak, C. H. and Fisher, M. A novel endothelin antagonist, A-127722, attenuates ischemic lesion size in rats with temporary middle cerebral artery occlusion. A diffusion and perfusion MRI study. Stroke 29, 850-858 (1998).
45. Del Zoppo, G. J., Schmid-Schönbein, G. W., Mori, E., Copeland, B. R. and Chang, C.-M. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke 22, 1276-1283 (1991).
46. 14C)Iodoantipyrine in the mouse. J. Cerebr. Blood Flow Metab. 8, 121-129 (1988).
47. Kohno, K., Hoehn-Berlage, M., Mies, G., Back, T. and Hossmann, K.-A. Relationship between diffusion-weighted MR images, cerebral blood flow, and energy state in experimental brain infarction. Magn. Reson. Imag. 13, 73-80 (1995).
48. 2) and apparent diffusion coefficient after permanent middle cerebral artery occlusion in the rat: temporal evolution, regional extent, and comparison with histology. Magn. Reson. Med. 34, 824-834 (1995).
49. Kitagawa, K., Matsumoto, M., Yang, G. M., Mabuchi, T., Yagita, Y., Hori, M. and Yanagihara, T. Cerebral-ischemia after bilateral carotid-artery occlusion and intraluminal suture occlusion in mice - evaluation of the patency of the posterior communicating artery. J. Cerebr. Blood Flow Metab. 18, 570-579 (1998).