Cycle changing the medium results in increased nisin productivity per cell in Lactococcus lactis

Biotechnology Letters

Volumn 31, Issue 3, 2009, Pages 415-421

  Simsek, Ömer ^a,b   Saris, Per E J ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b ANKARA UNIVERSITY   (Turkey)

Author keywords

Cycle changing medium; Feedback inhibition; Lactococcus lactis; Nisin production

Indexed keywords

BIOCHEMICAL ENGINEERING;

CYCLE CHANGING MEDIUM; FEEDBACK INHIBITION; LACTOCOCCUS LACTIS; NISIN PRODUCTION; PRODUCTION STATE;

ANTIBIOTICS;

NISIN;

ARTICLE; BIOTECHNOLOGY; CHEMISTRY; CULTURE MEDIUM; GROWTH, DEVELOPMENT AND AGING; LACTOCOCCUS LACTIS; METABOLISM; METHODOLOGY; TIME;

BIOTECHNOLOGY; CULTURE MEDIA; LACTOCOCCUS LACTIS; NISIN; TIME FACTORS;

LACTOCOCCUS LACTIS;

EID: 59149088847     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-008-9891-2     Document Type: Article

References (18)

1. MN Amiali C Lacroix RE Simard 1998 High nisin Z production by Lactococcus lactis UL719 in whey permeate with aeration World J Microbiol Biotechnol 14 887 894
2. N Bertrand I Fliss C Lacroix 2001 High nisin-Z production during repeated-cycle batch cultures in supplemented whey permeate using immobilized Lactococcus lactis UL719 Int Dairy J 11 953 960
3. JB Delves-Broughton 1990 Nisin and its uses as a food preservative Food Technol 44 100 117
4. P Desjardins J Meghorous C Lacroix 2001 Effect of aeration and dilution rate on nisin Z production during continuous fermentation with free and immobilized Lactococcus lactis UL719 in supplemented whey permeate Int Dairy J 11 943 951
5. L de Vuyst EJ Vandamme 1994
6. T Graeffe H Rintala L Paulin 1991
7. NP Guerra LP Castro 2003 Enhancement of nisin production by Lactococcus lactis in periodically re-alkalized cultures Biotechnol Appl Biochem 38 157 167
8. J Hakovirta J Reunanen PEJ Saris 2006 Bioassay for nisin in milk, processed cheese, salad dressings, canned tomatoes, and liquid egg Appl Environ Microbiol 72 1001 1005
9. W Lv W Cong Z Cai 2004 Nisin production by Lactococcus lactis subsp. lactis under nutritional limitation in fed-batch culture Biotechnol Lett 26 235 238
10. M Papagianni G Avramidis G Filiousis 2007 Investigating the relationship between the specific glucose uptake rate and nisin production in aerobic batch and fed-batch glucostat cultures of Lactococcus lactis Enzyme Microb Technol 40 1557 1563
11. M Qiao MJ Omaetxebarria R Ra 1997 Isolation of a Lactococcus lactis strain with high resistance to nisin and increased nisin production Biotechnol Lett 19 199 202
12. H Shimizu T Mizuguchi E Tanaka 1999 Nisin production by a mixed-culture system consisting of Lactococcus lactis and Kluyveromyces marxianus Appl Environ Microbiol 65 3134 3141
13. H Siegumfeldt KB Rechinger M Jakobsen 2000 Dynamic changes of intracellular pH in individual Lactic acid bacterium cells response to a rapid drop in extracellular pH Appl Environ Microbiol 66 2330 2335
14. K Sonomoto N Chinachoti N Endo 2000 Biosynthetic production of nisin Z by immobilized Lactococcus lactis IO-1 J Mol Catal B Enzym 10 325 334
15. M Tolonen PEJ Saris M Siika-Aho 2004 Production of nisin with continuous adsorption to amberlite XAD-4 resin using Lactococcus lactis N8 and L. lactis LAC48 Appl Microbiol Biotechnol 63 659 665
16. RE Wirawan NA Klesse RW Jack 2006 Molecular characterization of a novel nisin variant produced by Streptococcus uberis Appl Environ Microbiol 72 1148 1156
17. R Yang MC Johnson B Ray 1992 Novel method to extract large amounts of bacteriocins from lactic acid bacteria Appl Environ Microbiol 58 3355 3359
18. PL Yu NW Gunn WS Kim 2002 Lactate removal by anion exchange resin improves nisin production by Lactococcus lactis Biotechnol Lett 24 59 64