-
1
-
-
0038406789
-
Biology of hematopoietic stem cells and progenitors: Implications for clinical application
-
doi: 10.1146/annurev.immunol.21.120601.141007
-
Kondo M, Wagers AJ, Manz MG, Prohaska SS, Scherer DC, Beilhack GF et al (2003) Biology of hematopoietic stem cells and progenitors: Implications for clinical application. Annu Rev Immunol 21:759-806 doi: 10.1146/ annurev.immunol.21.120601.141007
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 759-806
-
-
Kondo, M.1
Wagers, A.J.2
Manz, M.G.3
Prohaska, S.S.4
Scherer, D.C.5
Beilhack, G.F.6
-
2
-
-
33747332700
-
FLT3 in normal hematopoiesis and acute myeloid leukemia
-
doi: 10.1634/stemcells.2005-0519
-
Parcells BW, Ikeda AK, Simms-Waldrip T, Moore TB, Sakamoto KM (2006) FLT3 in normal hematopoiesis and acute myeloid leukemia. Stem Cells 24:1174-1184 doi: 10.1634/stemcells.2005-0519
-
(2006)
Stem Cells
, vol.24
, pp. 1174-1184
-
-
Parcells, B.W.1
Ikeda, A.K.2
Simms-Waldrip, T.3
Moore, T.B.4
Sakamoto, K.M.5
-
3
-
-
0036720398
-
The roles of FLT3 in hematopoiesis and leukemia
-
doi: 10.1182/blood-2002-02-0492
-
Gilliland DG, Griffin JD (2002) The roles of FLT3 in hematopoiesis and leukemia. Blood 100:1532-1542 doi: 10.1182/blood-2002-02-0492
-
(2002)
Blood
, vol.100
, pp. 1532-1542
-
-
Gilliland, D.G.1
Griffin, J.D.2
-
4
-
-
0025905181
-
Expression cloning of an activin receptor, a predicted transmembrane serin kinase
-
doi: 10.1016/0092-8674(91)90549-E
-
Mathews LS, Vale WW (1991) Expression cloning of an activin receptor, a predicted transmembrane serin kinase. Cell 65:973-982 doi: 10.1016/ 0092-8674(91)90549-E
-
(1991)
Cell
, vol.65
, pp. 973-982
-
-
Mathews, L.S.1
Vale, W.W.2
-
5
-
-
0025969518
-
Isolation and chromosomal localization of a novel FMS-like tyrosine kinase
-
doi: 10.1016/0888-7543(91)90270-O
-
Rosnet O, Mattei MG, Marchetto S, Birnbaum D (1991) Isolation and chromosomal localization of a novel FMS-like tyrosine kinase. Genomics 9:380-385 doi: 10.1016/0888-7543(91)90270-O
-
(1991)
Genomics
, vol.9
, pp. 380-385
-
-
Rosnet, O.1
Mattei, M.G.2
Marchetto, S.3
Birnbaum, D.4
-
6
-
-
0027301288
-
Human FLT3/FLK2 gene: cDNA cloning and expression in hematopoietic cells
-
Rosnet O, Schiff C, Pebusque MJ et al (1993) Human FLT3/FLK2 gene: CDNA cloning and expression in hematopoietic cells. Blood 82:1110-1119
-
(1993)
Blood
, vol.82
, pp. 1110-1119
-
-
Rosnet, O.1
Schiff, C.2
Pebusque, M.J.3
-
7
-
-
0032519768
-
c-kit Ligand and Flt3 ligand: Stem/progenitor factors with overlapping yet distinct activities
-
Lyman SD, Jacobsen SE (1998) c-kit Ligand and Flt3 ligand: Stem/ progenitor factors with overlapping yet distinct activities. Blood 91:1101-1134
-
(1998)
Blood
, vol.91
, pp. 1101-1134
-
-
Lyman, S.D.1
Jacobsen, S.E.2
-
8
-
-
20244387299
-
Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential. A revised road map for adult blood lineage commitment
-
doi: 10.1016/j.cell.2005.02.013
-
Adolfsson J, Mansson R, Buza-Vidas N et al (2005) Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential. A revised road map for adult blood lineage commitment. Cell 121:295-306 doi: 10.1016/j.cell.2005.02.013
-
(2005)
Cell
, vol.121
, pp. 295-306
-
-
Adolfsson, J.1
Mansson, R.2
Buza-Vidas, N.3
-
9
-
-
0034749999
-
Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity
-
doi: 10.1016/S1074-7613(01)00220-5
-
Adolfsson J, Borge OJ, Bryder D et al (2001) Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity 15:659-669 doi: 10.1016/S1074-7613(01)00220-5
-
(2001)
Immunity
, vol.15
, pp. 659-669
-
-
Adolfsson, J.1
Borge, O.J.2
Bryder, D.3
-
10
-
-
0027955112
-
+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells
-
doi: 10.1073/pnas.91.2.459
-
+ human bone marrow cells and is involved in the proliferation of early progenitor/ stem cells. Proc Natl Acad Sci USA 91:459-463 doi: 10.1073/pnas.91.2.459
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 459-463
-
-
Small, D.1
Levenstein, M.2
Kim, E.3
-
11
-
-
0041743233
-
+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: Distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells
-
doi: 10.1182/blood-2002-06-1694
-
+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: Distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells. Blood 102:881-886 doi: 10.1182/ blood-2002-06-1694
-
(2003)
Blood
, vol.102
, pp. 881-886
-
-
Sitnicka, E.1
Buza-Vidaz, N.2
Larsson, S.3
Nygren, J.M.4
Liuba, K.5
Jacobsen, S.E.6
-
12
-
-
0031019451
-
+ progenitors to sustain long-term hematopoiesis in immune-deficient mice after ex vivo retroviral transduction
-
+ progenitors to sustain long-term hematopoiesis in immune-deficient mice after ex vivo retroviral transduction. Blood 89:446-456
-
(1997)
Blood
, vol.89
, pp. 446-456
-
-
Dao, M.A.1
Hannum, C.H.2
Kohn, D.B.3
Nolta, J.A.4
-
13
-
-
0028358913
-
Frequency analysis of human primitive haematopoietic stem cells subsets using a cobblestone area forming cell assay
-
Breems DA, Blockland EA, Neben S, Ploemacher RE (1994) Frequency analysis of human primitive haematopoietic stem cells subsets using a cobblestone area forming cell assay. Leukemia 8:1095-1104
-
(1994)
Leukemia
, vol.8
, pp. 1095-1104
-
-
Breems, D.A.1
Blockland, E.A.2
Neben, S.3
Ploemacher, R.E.4
-
14
-
-
18344418672
-
Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase
-
Rappold I, Ziegler BL, Köhler I, Marchetto S, Rosnet O, Birnbaum D et al (1997) Functional and phenotypic characterization of cord blood and bone marrow subsets expressing FLT3 (CD135) receptor tyrosine kinase. Blood 90:111-125
-
(1997)
Blood
, vol.90
, pp. 111-125
-
-
Rappold, I.1
Ziegler, B.L.2
Köhler, I.3
Marchetto, S.4
Rosnet, O.5
Birnbaum, D.6
-
15
-
-
0028318788
-
Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs
-
doi: 10.1038/368643a0
-
Hannum C, Culpepper J, Campbell D et al (1994) Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs. Nature 368:643-648 doi: 10.1038/368643a0
-
(1994)
Nature
, vol.368
, pp. 643-648
-
-
Hannum, C.1
Culpepper, J.2
Campbell, D.3
-
16
-
-
0028203747
-
Cloning of the human homologue of the murine flt3 ligand: A growth factor for early hematopoietic progenitor cells
-
Lyman SD, James L, Johnson L et al (1994) Cloning of the human homologue of the murine flt3 ligand: A growth factor for early hematopoietic progenitor cells. Blood 83:2795-2801
-
(1994)
Blood
, vol.83
, pp. 2795-2801
-
-
Lyman, S.D.1
James, L.2
Johnson, L.3
-
17
-
-
0029100754
-
Expression of the flt-3 receptor and its ligand on hematopoietic cells
-
Brasel K, Escobar S, Anderberg R, deVries P, Gruss HJ, Lyman SD (1995) Expression of the flt-3 receptor and its ligand on hematopoietic cells. Leukemia 9:1212-1218
-
(1995)
Leukemia
, vol.9
, pp. 1212-1218
-
-
Brasel, K.1
Escobar, S.2
Anderberg, R.3
deVries, P.4
Gruss, H.J.5
Lyman, S.D.6
-
18
-
-
0028556373
-
The flt3 ligand: A hematopoietic stem cell factor whose activities are distinct from steel factor
-
Lyman SD, Brasel K, Rousseau AM, Williams DE (1994) The flt3 ligand: A hematopoietic stem cell factor whose activities are distinct from steel factor. Stem Cells 12:99-107
-
(1994)
Stem Cells
, vol.12
, pp. 99-107
-
-
Lyman, S.D.1
Brasel, K.2
Rousseau, A.M.3
Williams, D.E.4
-
19
-
-
0029957070
-
Flt3 ligand supports the differentiation of early B-cell progenitors in the presence of interleukin-11 and interleukin-7
-
doi: 10.1002/eji.1830260715
-
Ray RJ, Paige CJ, Furlanger C, Lyman SD, Rotapel R (1996) Flt3 ligand supports the differentiation of early B-cell progenitors in the presence of interleukin-11 and interleukin-7. Eur J Immunol 26:1504-1510 doi: 10.1002/eji.1830260715
-
(1996)
Eur J Immunol
, vol.26
, pp. 1504-1510
-
-
Ray, R.J.1
Paige, C.J.2
Furlanger, C.3
Lyman, S.D.4
Rotapel, R.5
-
20
-
-
0031000903
-
Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood
-
Piacibello W, Sanavio F, Garetto L et al (1997) Extensive amplification and self-renewal of human primitive hematopoietic stem cells from cord blood. Blood 89:2644-2653
-
(1997)
Blood
, vol.89
, pp. 2644-2653
-
-
Piacibello, W.1
Sanavio, F.2
Garetto, L.3
-
21
-
-
0029977501
-
-) human hematopoietic cells: Novel responses to FLT3-ligand and thrombopoietin
-
doi: 10.1084/jem.183.6.2551
-
-) human hematopoietic cells: Novel responses to FLT3-ligand and thrombopoietin. J Exp Med 18:2551-2558 doi: 10.1084/jem.183.6.2551
-
(1996)
J Exp Med
, vol.18
, pp. 2551-2558
-
-
Petzer, A.L.1
Zandstra, P.W.2
Piret, J.M.3
Eaves, C.J.4
-
22
-
-
0028323099
-
The expression of FMS, KIT and FLT3 in hematopoietic malignancies
-
doi: 10.3109/10428199409056285
-
Birg F, Rosnet O, Carbuccia N, Birnbaum D (1994) The expression of FMS, KIT and FLT3 in hematopoietic malignancies. Leuk Lymphoma 13:223-227 doi: 10.3109/10428199409056285
-
(1994)
Leuk Lymphoma
, vol.13
, pp. 223-227
-
-
Birg, F.1
Rosnet, O.2
Carbuccia, N.3
Birnbaum, D.4
-
23
-
-
9144269029
-
FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells
-
doi: 10.1182/blood-2003-06-1969
-
Zheng R, Levis M, Piloto O et al (2004) FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells. Blood 103:267-274 doi: 10.1182/blood-2003-06-1969
-
(2004)
Blood
, vol.103
, pp. 267-274
-
-
Zheng, R.1
Levis, M.2
Piloto, O.3
-
24
-
-
0141836914
-
FLT3: It does matter in leukemia
-
doi: 10.1038/sj.leu.2403099
-
Levis M, Small D (2003) FLT3: It does matter in leukemia. Leukemia 17:1738-1752 doi: 10.1038/sj.leu.2403099
-
(2003)
Leukemia
, vol.17
, pp. 1738-1752
-
-
Levis, M.1
Small, D.2
-
25
-
-
0036624916
-
A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo
-
doi: 10.1182/blood.V99.11.3885
-
Levis M, Allenbach J, Tse KF et al (2002) A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo. Blood 99:3885-3891 doi: 10.1182/blood.V99.11.3885
-
(2002)
Blood
, vol.99
, pp. 3885-3891
-
-
Levis, M.1
Allenbach, J.2
Tse, K.F.3
-
26
-
-
4444342401
-
Pediatric AML primary samples with FLT3/ITD mutations are preferentially killed by FLT3 inhibition
-
doi: 10.1182/blood-2004-03-1034
-
Brown P, Meshinchi S, Levis M, Alonzo TA, Gerbing R, Lange B et al (2004) Pediatric AML primary samples with FLT3/ITD mutations are preferentially killed by FLT3 inhibition. Blood 104:1841-1849 doi: 10.1182/blood-2004-03-1034
-
(2004)
Blood
, vol.104
, pp. 1841-1849
-
-
Brown, P.1
Meshinchi, S.2
Levis, M.3
Alonzo, T.A.4
Gerbing, R.5
Lange, B.6
-
27
-
-
11244300074
-
FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression
-
doi: 10.1182/blood-2004-06-2498
-
Brown P, Levis M, Shurtleff S, Campana D, Downing J, Small D (2005) FLT3 inhibition selectively kills childhood acute lymphoblastic leukemia cells with high levels of FLT3 expression. Blood 105:812-820 doi: 10.1182/blood-2004-06-2498
-
(2005)
Blood
, vol.105
, pp. 812-820
-
-
Brown, P.1
Levis, M.2
Shurtleff, S.3
Campana, D.4
Downing, J.5
Small, D.6
-
28
-
-
1842420032
-
Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia
-
doi: 10.1182/blood-2003-11-3775
-
Smith DM, Levis M, Beran M, Giles F, Kanarjian H, Berg K et al (2004) Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia. Blood 103:3669-3676 doi: 10.1182/blood-2003-11-3775
-
(2004)
Blood
, vol.103
, pp. 3669-3676
-
-
Smith, D.M.1
Levis, M.2
Beran, M.3
Giles, F.4
Kanarjian, H.5
Berg, K.6
-
29
-
-
9144233483
-
Inhibitory effect of imatinib on normal progenitor cells in vitro
-
doi: 10.1182/blood-2003-05-1535
-
Bartolovic K, Balabanov S, Hartmann U, Komor M, Bühring HJ, Möhle R et al (2004) Inhibitory effect of imatinib on normal progenitor cells in vitro. Blood 103:523-529 doi: 10.1182/ blood-2003-05-1535
-
(2004)
Blood
, vol.103
, pp. 523-529
-
-
Bartolovic, K.1
Balabanov, S.2
Hartmann, U.3
Komor, M.4
Bühring, H.J.5
Möhle, R.6
-
30
-
-
0032402140
-
Highly efficient transduction of the green fluorescent protein gene in human umbilical cord blood stem cells capable of cobblestone formation in long-term cultures and multilineage engraftment of immunodeficient mice
-
Van Hennink PB, Verstegen MM, Bierhuizen MF, Limon A, Wognum AW, Cancelas JA et al (1998) Highly efficient transduction of the green fluorescent protein gene in human umbilical cord blood stem cells capable of cobblestone formation in long-term cultures and multilineage engraftment of immunodeficient mice. Blood 92:4013-4022
-
(1998)
Blood
, vol.92
, pp. 4013-4022
-
-
Van Hennink, P.B.1
Verstegen, M.M.2
Bierhuizen, M.F.3
Limon, A.4
Wognum, A.W.5
Cancelas, J.A.6
-
31
-
-
2342433801
-
In vitro and in vivo hematopoiesis
-
In: Zucker-Franklin D, Greaves MF, Grossi CE, Marmont AM (eds) 3rd edn. Arti Grafiche Salea, Milan
-
Moore MAS (2003) In vitro and in vivo hematopoiesis. In: Zucker-Franklin D, Greaves MF, Grossi CE, Marmont AM (eds) Atlas of blood cells: Function and pathology. 3rd edn. Arti Grafiche Salea, Milan, pp 1-38
-
(2003)
Atlas of Blood Cells: Function and Pathology
, pp. 1-38
-
-
Moore, M.A.S.1
-
32
-
-
0029876726
-
The transcriptional control of hematopoiesis
-
Shivdasani RA, Orkin SH (1996) The transcriptional control of hematopoiesis. Blood 87:4025-4039
-
(1996)
Blood
, vol.87
, pp. 4025-4039
-
-
Shivdasani, R.A.1
Orkin, S.H.2
-
33
-
-
0037071391
-
Hematopoietic cytokines, transcription factors and lineage commitment
-
doi: 10.1038/sj.onc.1205318
-
Zhu J, Emmerson SG (2002) Hematopoietic cytokines, transcription factors and lineage commitment. Oncogene 21:3295-3313 doi: 10.1038/sj.onc.1205318
-
(2002)
Oncogene
, vol.21
, pp. 3295-3313
-
-
Zhu, J.1
Emmerson, S.G.2
|