Aldo-keto reductases from the AKR1B subfamily: Retinoid specificity and control of cellular retinoic acid levels

Chemico-Biological Interactions

Volumn 178, Issue 1-3, 2009, Pages 171-177

  Ruiz, F Xavier ^a   Gallego, Oriol ^a   Ardèvol, Albert ^b   Moro, Armando ^a   Domínguez, Marta ^c   Alvarez, Susana ^c   Alvarez, Rosana ^c   de Lera, Angel R ^c   Rovira, Carme ^b,d   Fita, Ignacio ^e   Parés, Xavier ^a   Farrés, Jaume ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b Laboratori de Modelització i Simulació Computacional   (Spain)

^c UNIVERSITY OF VIGO   (Spain)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^e INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

Author keywords

Aldo keto reductases; Aldose reductase; Cancer; Protein structure; Retinoic acid; Tumor marker

Indexed keywords

ALDEHYDE REDUCTASE; ALDO KETO REDUCTASE 1B1; ALDO KETO REDUCTASE 1B10; CYCLOHEXENE DERIVATIVE; RETINOIC ACID; RETINOID; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CANCER RISK; CARCINOGENESIS; CATALYSIS; CELL DEDIFFERENTIATION; COMPARATIVE STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; MUTAGENESIS; NONHUMAN; PROTEIN EXPRESSION; STRUCTURE ANALYSIS;

ALCOHOL OXIDOREDUCTASES; BASE SEQUENCE; BIOCATALYSIS; CELLS, CULTURED; CLONING, MOLECULAR; DNA PRIMERS; DNA, COMPLEMENTARY; HELA CELLS; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; RETINOIDS; SUBSTRATE SPECIFICITY; TRETINOIN;

EID: 59049085002     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.10.027     Document Type: Article

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