Unbiased membrane permeability parameters for gabapentin using boundary layer approach

AAPS Journal

Volumn 7, Issue 1, 2005, Pages

  Madan, Jitender ^a,c   Chawla, Garima ^a   Arora, Vinod ^b   Malik, Rajiv ^b   Bansal, Arvind K ^a  

^a SAS Nagar   (India)

^b RANBAXY RESEARCH LABORATORIES   (India)

^c CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Carrier mediated transport; Concentration dependent; Gabapentin; Intestinal perfusion; Permeability

Indexed keywords

GABAPENTIN;

ANIMAL EXPERIMENT; ARTICLE; CALCULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIET RESTRICTION; DRUG ABSORPTION; DRUG PENETRATION; INTESTINE PERFUSION; MALE; MEMBRANE MODEL; MEMBRANE PERMEABILITY; MICHAELIS CONSTANT; NONHUMAN; PASSIVE TRANSPORT; RAT; SMALL INTESTINE ABSORPTION;

ALGORITHMS; AMINES; ANIMALS; ANTICONVULSANTS; BIOLOGICAL TRANSPORT; CELL MEMBRANE PERMEABILITY; CYCLOHEXANECARBOXYLIC ACIDS; DIFFUSION; GAMMA-AMINOBUTYRIC ACID; HUMANS; INTESTINAL ABSORPTION; JEJUNUM; MALE; PHENOLSULFONPHTHALEIN; RATS; RATS, SPRAGUE-DAWLEY; WATER;

EID: 27644444057     PISSN: 15221059     EISSN: 15221059     Source Type: Journal    
DOI: 10.1208/aapsj070121     Document Type: Article

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