A novel small molecule, LAS-0811, inhibits alcohol-induced apoptosis in VL-17A cells

Biochemical and Biophysical Research Communications

Volumn 379, Issue 4, 2009, Pages 876-881

  Kim, Tae Hun ^a,b   Venugopal, Senthil K ^a   Zhu, Ming ^a   Wang, Si Si ^a,c   Lau, Derick ^a   Lam, Kit S ^a   Clemens, Dahn L ^d   Zern, Mark A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Ewha Womans University School of Medicine   (South Korea)

^c Basic Medical College   (China)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Alcohol; Liver; Nrf2; Oxidative stress; Small molecule

Indexed keywords

ALCOHOL; ANTIOXIDANT; APOPTOSIS INHIBITOR; GLUTATHIONE PEROXIDASE; GREEN FLUORESCENT PROTEIN; LAS 0811; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANTIOXIDANT RESPONSIVE ELEMENT; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; COMPETITIVE INHIBITION; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE;

APOPTOSIS; CELL LINE; CYTOPROTECTION; ETHANOL; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HEPATOCYTES; HUMANS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RESPONSE ELEMENTS;

EID: 58949089381     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.12.133     Document Type: Article

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