Ductal injection of JNK inhibitors before pancreas preservation prevents islet apoptosis and improves islet graft function

Human Gene Therapy

Volumn 20, Issue 1, 2009, Pages 73-85

  Noguchi, Hirofumi ^a,b,h   Matsumoto, Shinichi ^a   Onaca, Nicholas ^c   Naziruddin, Bashoo ^b,c   Jackson, Andrew ^b,c   Ikemoto, Tetsuya ^a   Shimoda, Masayuki ^d   Fujita, Yasutaka ^a   Chujo, Daisuke ^a   Iwanaga, Yasuhiro ^e   Nagata, Hideo ^f   Okitsu, Teru ^e   Kobayashi, Naoya ^g   Ueno, Hideki ^a   Chaussabel, Damien ^a   Grayburn, Paul ^d   Banchereau, Jacques ^a,b   Levy, Marlon F ^a,c  

^a BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^b BAYLOR UNIVERSITY   (United States)

^c BAYLOR HEALTH CARE SYSTEM   (United States)

^d BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^e KYOTO UNIVERSITY HOSPITAL   (Japan)

^f FUJITA HEALTH UNIVERSITY   (Japan)

^g OKAYAMA UNIVERSITY   (Japan)

^h BAYLOR RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PRESERVATION SOLUTION; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE INHIBITOR 11R; UNCLASSIFIED DRUG; UNIVERSITY OF WISCONSIN SOLUTION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GENETIC TRANSDUCTION; GLUCOSE BLOOD LEVEL; GRAFT PRESERVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; ISOLATED PANCREAS ISLET; MOUSE; NONHUMAN; NUDE MOUSE; PANCREAS DUCT; PANCREAS TRANSPLANTATION; SCID MOUSE; STREPTOZOCIN DIABETES; SWINE;

ANIMALS; APOPTOSIS; DIABETES MELLITUS, EXPERIMENTAL; ENZYME INHIBITORS; GRAFT SURVIVAL; HUMANS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MICE, NUDE; ORGAN PRESERVATION; ORGAN PRESERVATION SOLUTIONS; PANCREAS; SWINE; TISSUE AND ORGAN HARVESTING;

MUS; SUS;

EID: 58849155945     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2008.125     Document Type: Article

References (45)

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