Adenovirus-mediated FKBP12.6 overexpression induces hypertrophy and apoptosis in cultured neonatal cardiomyocytes

Clinical and Experimental Pharmacology and Physiology

Volumn 36, Issue 2, 2009, Pages 135-140

  Zhong, Jian ^a,b   Chen, Jing ^a,b   Cao, Tingbin ^a   Wang, Lijuan ^a   Zhang, Weiguo ^b   Liu, Daoyan ^a   Zhu, Zhiming ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b Cardiovascular and Neurological Consulting Institute   (United States)

Author keywords

Apoptosis; Cardiomyocytes; FKBP12.6; Hypertrophy; Signal transduction

Indexed keywords

COMPLEMENTARY DNA; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 12.6; GREEN FLUORESCENT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BAX; RAPAMYCIN; RYANODINE RECEPTOR 2; TRITIUM; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; DNA FRAGMENTATION; DNA SYNTHESIS; DOWN REGULATION; GENE INDUCTION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; PLASMID; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RAT; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CALCIUM; CELL ENLARGEMENT; CELLS, CULTURED; CLONING, MOLECULAR; DNA FRAGMENTATION; HUMANS; IMMUNOBLOTTING; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SIROLIMUS; TACROLIMUS BINDING PROTEINS; TRANSFECTION;

EID: 58849151764     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2008.05030.x     Document Type: Article

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