Early atherosclerosis in patients wih inflammatory bowel disease

European Review for Medical and Pharmacological Sciences

Volumn 10, Issue 1, 2006, Pages 7-11

  Papa, A ^a   Danese, S ^a   Urgesi, R ^a   Grillo, A ^a   Guglielmo, S ^a   Roberto, I ^a   Bonizzi, M ^a   Guidi, L ^a   De Vitis, I ^a   Santoliquido, A ^a   Fedeli, G ^a   Gasbarrini, G ^a   Gasbarrini, A ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

Atherosclerosis; Homocysteine; Inflammatory bowel disease; Vascular disease

Indexed keywords

HOMOCYSTEINE;

ARTERY WALL; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CLINICAL FEATURE; COMMON CAROTID ARTERY; CONTROLLED STUDY; ENTERITIS; HUMAN; HYPOTHESIS; IMMUNOPATHOLOGY; INFLAMMATORY DISEASE; INTIMA; MAJOR CLINICAL STUDY; MORBIDITY; MORTALITY; PATHOGENESIS; PREVALENCE; RISK ASSESSMENT; THROMBOSIS; TUNICA MEDIA; VASCULAR DISEASE;

AGE FACTORS; ATHEROSCLEROSIS; CAROTID ARTERIES; CASE-CONTROL STUDIES; COLITIS, ULCERATIVE; CROHN DISEASE; HOMOCYSTEINE; HUMANS; TUNICA INTIMA; TUNICA MEDIA; ULTRASONOGRAPHY;

EID: 33644537944     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Fiocchi C. Intestinal inflammation: a complex interplay of immune and nonimmune cellinteractions. Am J Physiol 1997; 273: G769-G775.
2. Hatoum OA, Binion DG. The vasculature and inflammatory bowel disease. Contribution to pathogenesis and clinical pathology. Inflamm Bowel Dis 2005; 11: 304-313.
3. Laroux FS, Grisham MB. Immunological basis of inflammatory bowel disease: Role of the microcirculation. Microcirculation 2001; 8: 283-301.
4. Wakefield AJ, Sawyerr AM, Dhillon AP et al. Pathogenesis of Crohn's disease: multifocal gastrointestinal infarction. Lancet 1989; 2: 1057-1062.
5. Dhillon AP, Anthony A, Sim R, et al. Mucosal capillary thrombi in rectal biopsies. Histopathology 1992; 21: 127-133.
6. Hatoum OA, Binion DG, Otterson MF, et al. Acquired microvascular dysfunction in inflammatory bowel disease: loss of nitric oxide-mediated vasodilation. Gastroenterology 2003; 125: 58-69.
7. Talbot RW, Heppell J, Dozois RR, et al. Vascular complications of inflammatory bowel disease. Mayo Clin Proc 1986; 61: 140-145.
8. Edwards FC, Truelove SC. The course and prognosis of ulcerative colitis. Part III. Complications. Gut 1964; 5: 1-22.
9. Jackson LM, O'Gorman PJ, O'Connell J, et al. Thrombosis in inflammatory bowel disease: clinical setting, procoagulant profile and Factor V Leiden. Q J Med 1997; 90: 183-188.
10. Graef V, Baggenstoss AH, Sauer WG, et al. Venous thrombosis occurring in non-specific ulcerative colitis. A necropsy study. Arch Intern Med 1966; 117: 377-382.
11. Webberly MJ, Hart MT, Melikian V. Thromboembolism in inflammatory bowel disease: role of platelets. Gut 1993; 34: 247-251.
12. Bernestein CN, Blanchard JF, Houston DS, et al. The incidence of deep venous thrombosis and pulmonary embolism among patients with inflammatory bowel disease: a population-based cohort study. Thromb Haemost 2001; 85: 430-434.
13. Miehsler W, Reinisch W, VALIC E, et al. Is inflammatory bowel disease an independent and disease specific risk factor for thromboembolism? Gut 2004; 53: 542-548.
14. Grip O, Svensson PJ, Lindgren S. Inflammatory bowel disease promotes venous thrombosis earlier in life. Scand J Gastroenterol 2000; 35: 619-623.
15. Kouttoubakis IE. Therapy insight: Vascular complications in patients with inflammatory bowel disease. Nat Clin Pract Gastroenterol Hepatol 2005; 2: 266-272.
16. Younes-Mhenni S, Derex L, Berruyer M, et al. Large-artery stroke in a young patients with Crohn's disease. Role of vitamin B6 deficiency-induced hyperhomocysteinemia. J Neurol Sci 2004; 991: 113-115.
17. Levy PJ, Tabares AH, Olin JW. Lower extremity arterial occlusion in young patients with Crohn's colitis and premature atherosclerosis: report of six cases. Am J Gastorenterol 1997; 92: 494-497.
18. Schneiderman JH, Sharpe JA, Sutton DM. Cerebral and retinal vascular complications of inflammatory bowel disease. Ann Neurol 1979; 5: 331-337.
19. Mutlu B, Ermeydan CMH, Enç F, et al. Acute myocardial infarction in a young woman with severe ulcerative colitis. Int J Cardiol 2002; 83: 183-185.
20. Novacek G, Haumer M, Schima W, et al. Aortic mural thrombi in patients with inflammatory bowel disease: report of two cases and review of the literature. Inflamm Bowel Dis 2004; 10: 430-435.
21. Solem CA. Loftus EV, Tremaine WJ, Sandborn WJ. Venous thromboembolism in inflammatory bowel disease. Am J Gastroenterol 2004; 99: 97-101.
22. Thompson NP, Wakefield AJ, Pounder RE. Inherited disorders of coagulation appear to protect against inflammatory bowel disease. Gastroenterology 1995; 108: 1011-1015.
23. Papa A, Danese S, Gasbarrini A, et al. Review article: Potential therapeutic applications and mechanisms of action of heparin in inflammatory bowel disease. Aliment Pharmacol Ther 2000; 14: 1403-1409.
24. van Doornum S, McColl G, Wicks IP. Accelerated atherosclerosis. An extraarticular feature of rheumatoid arthritis? Arthritis Rheum 2002; 46: 862-873.
25. Selzer F, Sutton-Tyrrell K, Fitzgerald SG, et al. Comparison of risk factor for vascular disease in the carotid artery and aorta in women with systemic lupus erythematosus. Arthritis Rheum 2004; 50: 151-159.
26. Ward MM. Premature morbidity from cardiovascular and cerebrovascular diseases in women with systemic lupus erythematosus. Arthritis Rheum 1999; 42: 338-346.
27. Symmons DP, Jones MA, Scott DL, et al. Long term mortality outcome in patients with rheumatoid arthritis: early presenters continue to do well. J Rheumatol 1998; 25: 1072-1077.
28. Bots ML, Duk JM, Oren A, et al. Carotid intima-media thickness, arterial stiffness and risk of cardiovascular disease: current evidence. J Hypertens 2002; 20: 2317-2325.
29. O'Learly DH, Polak JF, Kronmal RA, et al. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. N Engl J Med 1999; 340: 14-22.
30. Davis PH, Dawson JD, Riley WA, et al. Carotid intimal-medial thickness is related to cardiovascular risk factors measured from childhood through middle age. Circulation 2001; 104: 2815-2819.
31. Kumeda Y, Masaaki I, Goto H, et al. Increased thickness of the arterial intima-media detected by ultrasonography in patients with rheumatoid arthritis. Arthritis Rheum 2002; 46: 1489-1497.
32. Durga J, Verhoef P, Bots ML, et al. Homocysteine and carotid intima-media thickness: a critical appraisal of the evidence. Atherosclerosis 2004; 176: 1-19.
33. Alkaabi JK, Ho M, Levison R, et al. Rheumatoid arthritis and macrovascular disease. Rheumatology 2003;42: 292-297.
34. Park YB, Ahn CW, Choi HK, et al. Atherosclerosis in rheumatoid arthritis. Morphologic evidence obtained by carotid ultrasound. Arthritis Rheum 2002; 46: 1714-1719.
35. Paoletti R, Gotto AM, DP Hauar. Inflammation in atherosclerosis and implications for therapy. Circulation 2004; 109 (Suppl III): 20-26.
36. Libby P, Ridker PM, Maseri A. Inflammation and atherosclerosis. Circulation 2002; 105: 1135-1143.
37. Ross R. Atherosclerosis an inflammatory disease. N Engl J Med 1999; 340: 115-126.
38. The homocysteine studies collaboration. Homocysteine and risk of ischemic heart disease and stroke-a meta-analysis. JAMA 2002; 288: 2015-2099.
39. Ford ES, Smith SJ, Stroup DF et al. Homocys(e)ine and cardiovascular disease: a systematic review of the evidence with special emphasis on case-control studies and nested case-control studies. Int J Epidemiol 2002; 31: 59-70.
40. Cattaneo M. Hyperhomocysteinemia, atherosclerosis and thrombosis. Thromb Haemost 1999; 81: 165-176.
41. Welch GN, Loscalzo J. Mechanisms of disease: homocysteine and atherothrombosis. N Engl J Med 1998; 338- 1042-1050.
42. Papa A, De Stefano V, Danese S, et al. Hyperhomocysteinemia and prevalence of polymorphisms of homocysteine metabolism related enzymes in patients with inflammatory bowel disease. Am J Gastroenterol 2001; 96: 2677-2682.
43. Cattaneo M, Vecchi M, Zighetti ML, et al. High prevalence of hyperhomocysteinemia in patients with inflammatory bowel disease: a pathogenetic link with thromboembolic complications? Thromb Haemost 1998; 80: 542-545.
44. Bjerregaard Larsen T, Nederby Nielsen J, et al. Hyperhomocysteinemia, coagulation pathway activation and thrombophilia in patients with inflammatory bowel disease. Scand J Gastroenterol 2002; 37: 62-67.
45. Oldenburg B, Funheer R, Van Der Griend R, et al. Homocysteine in inflammatory bowel disease: a risk factor for thromboembolic complications? Am J Gastroenterol 2000; 95: 2825-2830.
46. Koutroubakis IE, Dilaveraki E, Vlachonikolis IG, et al. Hyperhomocysteinemia in Greek patients with inflammatory bowel disease. Dig Dis Sci 2000; 45: 2347-2351.
47. Danese S, Sgambato A, Papa A, et al. Homocysteine triggers mucosal microvascular activation in inflammatory bowel disease. Am J Gastroenterol 2005; 100: 886-895.
48. Morgenstern I, Raumakers MT, Pepers WH, et al. Homocysteine, cysteine, and glutathione in human intestinal mucosa: elevated levels of homocysteine in patients with inflammatory bowel disease. Dig Dis Sci 2003; 48: 2083-2090.
49. Saibeni S, Cattaneo M, Vecchi M, et al. Low vitamin B(6) plasma levels, a risk factor for thrombosis, in inflammatory bowel disease: role of inflammation and correlation with acute phase reactants. Am J Gastroenterol 2003; 98: 112-117.
50. Weiss N, Heydrick SJ, Postea O, et al. Influence of hyperhomocysteinemia on the cellular redox state-Impact on homocysteine-induced endothelial dysfunction. Clin Chem Lab Med 2003; 41: 1455-1461.
51. Stanger O, Weger M. Interactions of homocysteine, nitric oxide, folate and radicals in the progressively damaged endothelium. Clin Chem Lab Med 2003; 41: 1444-1454.
52. Hajjar KA. Homocysteine: a sulphurous fire. J Clin Invest 2001; 107: 663-664.
53. Feigin VL, anderson CS, Mhurchu CN. Systemic inflammation, endothelial dysfunction, dietary fatty acid and micronutrients as risk factors for stroke: a selective review. Cerebrovasc Dis 2002; 13: 219-224.
54. Stuglinger MC, Oka RK, Graft EE, et al. Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymettric dimethylarginine. Circulation 2003; 108: 933-938.
55. Hurlimann D, Forster A, Noll G, et al. Anti-tumor necrosis factor-a treatment improves endothelial function in patients with rheumatoid arthritis. Circulation 2002; 106: 2184-2187.