-
1
-
-
40049097826
-
What is the risk of mortality following diagnosis of multidrug-resistant HIV-1?
-
Grover D, Copas A, Green H, et al. What is the risk of mortality following diagnosis of multidrug-resistant HIV-1? J Antimicrob Chemother 2008; 61:705-713.
-
(2008)
J Antimicrob Chemother
, vol.61
, pp. 705-713
-
-
Grover, D.1
Copas, A.2
Green, H.3
-
3
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
Deng H, Liu R, Ellmeier W, et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996; 381:661 -666.
-
(1996)
Nature
, vol.381
, pp. 661-666
-
-
Deng, H.1
Liu, R.2
Ellmeier, W.3
-
4
-
-
0030002637
-
HIV-1 entry cofactor: Functional cDNA cloning of a seven transmembrane G protein coupled receptor
-
Feng Y, Broder C, Kennedy P, Berger E. HIV-1 entry cofactor: functional cDNA cloning of a seven transmembrane G protein coupled receptor. Science 1996; 272:872-877.
-
(1996)
Science
, vol.272
, pp. 872-877
-
-
Feng, Y.1
Broder, C.2
Kennedy, P.3
Berger, E.4
-
6
-
-
35548963749
-
Treatment with CCR5 antagonists: Which patient may have a benefit
-
Mueller MC, Bogner JR. Treatment with CCR5 antagonists: which patient may have a benefit. Eur J Med Res 2007; 12:441-452.
-
(2007)
Eur J Med Res
, vol.12
, pp. 441-452
-
-
Mueller, M.C.1
Bogner, J.R.2
-
7
-
-
35548998700
-
HIV coreceptors: From discovery and designation to new paradigms and promise
-
Alkhatib G, Berger EA. HIV coreceptors: from discovery and designation to new paradigms and promise. Eur J Med Res 2007; 12:375-384.
-
(2007)
Eur J Med Res
, vol.12
, pp. 375-384
-
-
Alkhatib, G.1
Berger, E.A.2
-
8
-
-
58849091572
-
Viral (HIV) entry: How does it work?
-
Jager H, editor, Springer;
-
Panos, Nelson. Viral (HIV) entry: how does it work? In: Jager H, editor. Entry inhibitoren ! neue Formen der HIV therapy. Springer; 2008. pp. 1-10.
-
(2008)
Entry inhibitoren ! neue Formen der HIV therapy
, pp. 1-10
-
-
Panos, N.1
-
10
-
-
0042376485
-
A new classification for HIV-1
-
Berger E, Doms R, Fenyo E, et al. A new classification for HIV-1. Nature 1998; 391:240.
-
(1998)
Nature
, vol.391
, pp. 240
-
-
Berger, E.1
Doms, R.2
Fenyo, E.3
-
12
-
-
0007643930
-
Association between CCR5 genotype and the clinical course of HIV-1 infection
-
de Roda Husman AM, Koot M, Cornelissen M, et al. Association between CCR5 genotype and the clinical course of HIV-1 infection. Ann Intern Med 1997; 127:882-890.
-
(1997)
Ann Intern Med
, vol.127
, pp. 882-890
-
-
de Roda Husman, A.M.1
Koot, M.2
Cornelissen, M.3
-
13
-
-
58849114325
-
-
Demarest J, Bonny T, Vavro C, et al. HIV-1 co-receptor tropism in treatment naive and experienced subjects [abstract H1136]. In: Program and Abstracts of the 44th International Conference on Antimicrobial Agents and Chemotherapy; 30 October-2 November 2004; Washington, DC. Washington, DC: American Society for Microbiology; 2004.
-
Demarest J, Bonny T, Vavro C, et al. HIV-1 co-receptor tropism in treatment naive and experienced subjects [abstract H1136]. In: Program and Abstracts of the 44th International Conference on Antimicrobial Agents and Chemotherapy; 30 October-2 November 2004; Washington, DC. Washington, DC: American Society for Microbiology; 2004.
-
-
-
-
14
-
-
22544456536
-
Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals
-
Brumme ZL, Goodrich J, Mayer HB, et al. Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals. J Infect Dis 2005; 192:466-474.
-
(2005)
J Infect Dis
, vol.192
, pp. 466-474
-
-
Brumme, Z.L.1
Goodrich, J.2
Mayer, H.B.3
-
15
-
-
14844333093
-
Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection
-
Moyle GJ, Wildfire A, Mandalia S, et al. Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection. J Infect Dis 2005; 191:866-872.
-
(2005)
J Infect Dis
, vol.191
, pp. 866-872
-
-
Moyle, G.J.1
Wildfire, A.2
Mandalia, S.3
-
16
-
-
0032103997
-
Chemokine receptors and the clinical course of HIV-1 infection
-
de Roda Husman AM, Schuitemaker H. Chemokine receptors and the clinical course of HIV-1 infection. Trends Microbiol 1998; 6:244-249.
-
(1998)
Trends Microbiol
, vol.6
, pp. 244-249
-
-
de Roda Husman, A.M.1
Schuitemaker, H.2
-
17
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
-
Berger EA, Murphy PM, Farber JM. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu Rev Immunol 1999; 17:657-700.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
Murphy, P.M.2
Farber, J.M.3
-
18
-
-
58849107368
-
CXCR4-tropic viruses are common among antiretroviral treated patients with detectable viremia and associated with lower treatment-mediated CD4 gains
-
abstract #43, 6 June, Denver, CO
-
Hunt P, Martin J, Bates M, et al. CXCR4-tropic viruses are common among antiretroviral treated patients with detectable viremia and associated with lower treatment-mediated CD4 gains [abstract #43]. In: 13th Conference on Retroviruses and Opportunistic Infections; 6 June 2006; Denver, CO.
-
(2006)
13th Conference on Retroviruses and Opportunistic Infections
-
-
Hunt, P.1
Martin, J.2
Bates, M.3
-
19
-
-
0742325043
-
The CCR5 and CXCR4 coreceptors - central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection
-
Moore JP, Kitchen SG, Pugach P, et al. The CCR5 and CXCR4 coreceptors - central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res Hum Retroviruses 2004; 20:111-126.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, pp. 111-126
-
-
Moore, J.P.1
Kitchen, S.G.2
Pugach, P.3
-
20
-
-
3042780489
-
Co-receptor antagonists as HIV-1 entry inhibitors
-
Shaheen F, Collman RG. Co-receptor antagonists as HIV-1 entry inhibitors. Curr Opin Infect Dis 2004; 17:7-16.
-
(2004)
Curr Opin Infect Dis
, vol.17
, pp. 7-16
-
-
Shaheen, F.1
Collman, R.G.2
-
21
-
-
0042895999
-
Analysis of baseline enfuvirtide (t20) susceptibility and co-receptor tropism in two-phase III study populations
-
abstract #557, 10-14 February, Boston, MA
-
Whitcomb JM, Huang W, Fransen S, et al. Analysis of baseline enfuvirtide (t20) susceptibility and co-receptor tropism in two-phase III study populations [abstract #557]. In: 10th Conference on Retroviruses and Opportunistic Infections; 10-14 February 2003; Boston, MA.
-
(2003)
10th Conference on Retroviruses and Opportunistic Infections
-
-
Whitcomb, J.M.1
Huang, W.2
Fransen, S.3
-
22
-
-
58849086483
-
-
Paxinos E, Fransen S, Huang W, et al. Measuring HIV-1 coreceptor tropism using a recombinant virus assay [abstract #2040]. In: Program and Abstracts of the 42th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); 27-30 September 2002; San Diego, CA.
-
Paxinos E, Fransen S, Huang W, et al. Measuring HIV-1 coreceptor tropism using a recombinant virus assay [abstract #2040]. In: Program and Abstracts of the 42th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); 27-30 September 2002; San Diego, CA.
-
-
-
-
23
-
-
33750872090
-
Co-receptor tropism in patients screening for ACTG 5211, a phase 2 study of Vicriviroc, a CCR5 inhibitor
-
abstract #655, 5-8 February, Denver, CO
-
Wilkin T, Su Z, Kuritzkes D, et al. Co-receptor tropism in patients screening for ACTG 5211, a phase 2 study of Vicriviroc, a CCR5 inhibitor [abstract #655], In: 13th Conference on Retroviruses and Opportunistic Infections; 5-8 February 2006; Denver, CO.
-
(2006)
13th Conference on Retroviruses and Opportunistic Infections
-
-
Wilkin, T.1
Su, Z.2
Kuritzkes, D.3
-
24
-
-
35548939825
-
The epidemiology of HIV coreceptor tropism
-
Hoffman C. The epidemiology of HIV coreceptor tropism. Eur J Med Res 2007; 12:385-390.
-
(2007)
Eur J Med Res
, vol.12
, pp. 385-390
-
-
Hoffman, C.1
-
25
-
-
0037379188
-
The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C
-
Cilliers T, Nhlapo J, Coetzer M, et al. The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C. J Virol 2003; 77:4449-4456.
-
(2003)
J Virol
, vol.77
, pp. 4449-4456
-
-
Cilliers, T.1
Nhlapo, J.2
Coetzer, M.3
-
26
-
-
0038805436
-
High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment
-
Johnston ER, Zijenah LS, Mutetwa S, et al. High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. J Virol 2003; 77:7682-7688.
-
(2003)
J Virol
, vol.77
, pp. 7682-7688
-
-
Johnston, E.R.1
Zijenah, L.S.2
Mutetwa, S.3
-
27
-
-
37849007568
-
Subtype-specific conformational differences within the V3 region of subtype B and subtype C human immunodeficiency virus type 1 Env proteins
-
Patel MB, Hoffman NG, Swanstrom R. Subtype-specific conformational differences within the V3 region of subtype B and subtype C human immunodeficiency virus type 1 Env proteins. J Virol 2008; 82:903-916.
-
(2008)
J Virol
, vol.82
, pp. 903-916
-
-
Patel, M.B.1
Hoffman, N.G.2
Swanstrom, R.3
-
29
-
-
0034690623
-
Genetic characterization of incident HIV type 1 subtype E and B strains from a prospective cohort of injecting drug users in Bangkok, Thailand
-
Subbarao S, Vanichseni S, Hu DJ, et al. Genetic characterization of incident HIV type 1 subtype E and B strains from a prospective cohort of injecting drug users in Bangkok, Thailand. AIDS Res Hum Retroviruses 2000; 16:699-707.
-
(2000)
AIDS Res Hum Retroviruses
, vol.16
, pp. 699-707
-
-
Subbarao, S.1
Vanichseni, S.2
Hu, D.J.3
-
30
-
-
34547128097
-
Coreceptor tropism in human immunodeficiency virus type 1 subtype D: High prevalence of CXCR4 tropism and heterogeneous composition of viral populations
-
Huang W, Eshleman SH, Toma J, et al. Coreceptor tropism in human immunodeficiency virus type 1 subtype D: high prevalence of CXCR4 tropism and heterogeneous composition of viral populations. J Virol 2007; 81:7885- 7893.
-
(2007)
J Virol
, vol.81
, pp. 7885-7893
-
-
Huang, W.1
Eshleman, S.H.2
Toma, J.3
-
31
-
-
0032519399
-
Differences in chemokine coreceptor usage between genetic subtypes of HIV-1
-
Tscherning C, Alaeus A, Fredriksson R, et al. Differences in chemokine coreceptor usage between genetic subtypes of HIV-1. Virology 1998; 241:181-188.
-
(1998)
Virology
, vol.241
, pp. 181-188
-
-
Tscherning, C.1
Alaeus, A.2
Fredriksson, R.3
-
32
-
-
34247555911
-
Relation between chemokine receptor use, disease stage, and HIV-1 subtypes A and D: Results from a rural Ugandan cohort
-
Kaleebu P, Nankya IL, Yirrell DL, et al. Relation between chemokine receptor use, disease stage, and HIV-1 subtypes A and D: results from a rural Ugandan cohort. J Acquir Immune Defic Syndr 2007; 45:28-33.
-
(2007)
J Acquir Immune Defic Syndr
, vol.45
, pp. 28-33
-
-
Kaleebu, P.1
Nankya, I.L.2
Yirrell, D.L.3
-
33
-
-
0042368609
-
Broad spectrum of coreceptor usage and rapid disease progression in HIV-1-infected individuals from Central African Republic
-
Bégaud E, Feindirongai G, Versmisse P, et al. Broad spectrum of coreceptor usage and rapid disease progression in HIV-1-infected individuals from Central African Republic. AIDS Res Hum Retroviruses 2003; 19:551 - 560.
-
(2003)
AIDS Res Hum Retroviruses
, vol.19
, pp. 551-560
-
-
Bégaud, E.1
Feindirongai, G.2
Versmisse, P.3
-
34
-
-
23244448235
-
Use of alternate coreceptors on primary cells by two HIV-1 isolates
-
Cilliers T, Willey S, Sullivan WM, et al. Use of alternate coreceptors on primary cells by two HIV-1 isolates. Virology 2005; 339:136-144.
-
(2005)
Virology
, vol.339
, pp. 136-144
-
-
Cilliers, T.1
Willey, S.2
Sullivan, W.M.3
-
35
-
-
58849162044
-
-
Stawiski E, Whitcomb J, Coakley E, et al. Co-receptor tropism predictions based on V3 loop sequence in antiretroviral-experienced patients are specific but insensitive for the detection of CXCR4-using variants [abstract #1-1-1028], In: Program and Abstracts of the 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); 17-20 September 2007; Chicago, IL
-
Stawiski E, Whitcomb J, Coakley E, et al. Co-receptor tropism predictions based on V3 loop sequence in antiretroviral-experienced patients are specific but insensitive for the detection of CXCR4-using variants [abstract #1-1-1028], In: Program and Abstracts of the 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); 17-20 September 2007; Chicago, IL
-
-
-
-
36
-
-
10744231634
-
Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 Env V3 loop sequences
-
Jensen MA, Li FS, van 't Wout AB, et al. Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 Env V3 loop sequences. J Virol 2003; 77:13376-13388.
-
(2003)
J Virol
, vol.77
, pp. 13376-13388
-
-
Jensen, M.A.1
Li, F.S.2
van 't Wout, A.B.3
-
37
-
-
34548261959
-
Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
-
Low AJ, Dong W, Chan D, et al. Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates. AIDS 2007; 21:F17-F24.
-
(2007)
AIDS
, vol.21
-
-
Low, A.J.1
Dong, W.2
Chan, D.3
-
38
-
-
33846623260
-
Development and characterization of a novel single-cycle recombinant-virus assay to determine human immunodeficiency virus type 1 coreceptor tropism
-
Whitcomb JM, Huang W, Fransen S, et al. Development and characterization of a novel single-cycle recombinant-virus assay to determine human immunodeficiency virus type 1 coreceptor tropism. Antimicrob Agents Chemother 2007; 51:566-575.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 566-575
-
-
Whitcomb, J.M.1
Huang, W.2
Fransen, S.3
-
39
-
-
35548983281
-
A multicenter, randomized, double-blind, comparative trial of a novel CCR5 antagonist, maraviroc versus efavirenz, both in combination with Combivir (zidovudine [ZDV]/lamivudine [3TC]), for the treatment of antiretroviral naive subjects infected with R5 HIV-1: Week 48 results of the MERIT study
-
abstract #WESS104, 22-25 July, Sydney, Australia
-
Saag M, Ive P, Heera J, et al. A multicenter, randomized, double-blind, comparative trial of a novel CCR5 antagonist, maraviroc versus efavirenz, both in combination with Combivir (zidovudine [ZDV]/lamivudine [3TC]), for the treatment of antiretroviral naive subjects infected with R5 HIV-1: week 48 results of the MERIT study [abstract #WESS104]. In: 4th IAS conference; 22-25 July 2007; Sydney, Australia.
-
(2007)
4th IAS conference
-
-
Saag, M.1
Ive, P.2
Heera, J.3
-
40
-
-
43749114431
-
Efficacy and safety of maraviroc plus optimized background therapy in treatment-experienced patients infected with CCR5-tropic HIV-1: 48-week combined analysis of the MOTIVATE studies
-
abstract #792, 3-6 February, Boston, MA
-
Hardy D, Reynes J, Konourina I, et al. Efficacy and safety of maraviroc plus optimized background therapy in treatment-experienced patients infected with CCR5-tropic HIV-1: 48-week combined analysis of the MOTIVATE studies [abstract #792]. In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2006; Boston, MA.
-
(2006)
15th Conference on Retroviruses and Opportunistic Infections
-
-
Hardy, D.1
Reynes, J.2
Konourina, I.3
-
41
-
-
58849153440
-
-
Gulick R, Su Z, Flexner C, et al. ACTG 5211: phase II study of the safety and efficacy of vicriviroc (VCV) in HIV-infected treatment-experienced subjects: 48 week results [abstract #TUAB102]. In: Program and abstracts of the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention; 22-25 July 2007; Sydney, Australia.
-
Gulick R, Su Z, Flexner C, et al. ACTG 5211: phase II study of the safety and efficacy of vicriviroc (VCV) in HIV-infected treatment-experienced subjects: 48 week results [abstract #TUAB102]. In: Program and abstracts of the 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention; 22-25 July 2007; Sydney, Australia.
-
-
-
-
42
-
-
48449104735
-
An enhanced version of the trofile HIV coreceptor tropism assay predicts emergence of CXCR4 use in ACTG5211 vicriviroc trial samples
-
abstract #869, 3-6 February, Boston, MA
-
Reeves J, Han D, Wilkin T, et al. An enhanced version of the trofile HIV coreceptor tropism assay predicts emergence of CXCR4 use in ACTG5211 vicriviroc trial samples [abstract #869]. In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections
-
-
Reeves, J.1
Han, D.2
Wilkin, T.3
-
43
-
-
27644510382
-
Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum antihuman immunodeficiency virus type 1 activity
-
Dorr P, Westby M, Dobbs S, et al. Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum antihuman immunodeficiency virus type 1 activity. Antimicrob Agents Chemother 2005; 49:4721-4732.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 4721-4732
-
-
Dorr, P.1
Westby, M.2
Dobbs, S.3
-
45
-
-
58849099353
-
-
Nelson M, Fisher M, Gonzalez-Garcia J, et al. Impact of baseline antiretroviral resistance status on efficacy outcomes among patients receiving maraviroc (MVC) plus an optimized background therapy (OBT) versus placebo (PBO) plus OBT in the MOTIVATE 1 and 2 trials [abstract #TUPE0119]. In: Program and Abstracts of the XVII International AIDS Conference; 3-8 August 2008; Mexico City, Mexico.
-
Nelson M, Fisher M, Gonzalez-Garcia J, et al. Impact of baseline antiretroviral resistance status on efficacy outcomes among patients receiving maraviroc (MVC) plus an optimized background therapy (OBT) versus placebo (PBO) plus OBT in the MOTIVATE 1 and 2 trials [abstract #TUPE0119]. In: Program and Abstracts of the XVII International AIDS Conference; 3-8 August 2008; Mexico City, Mexico.
-
-
-
-
46
-
-
56749180679
-
The incidence of severe liver enzyme abnormalities and hepatic adverse events in the Maraviroc Clinical Development Programme [poster LBP7.9/1]
-
24-27 October, Madrid, Spain
-
Hoepelman IM, Ayoub A, Heera J. The incidence of severe liver enzyme abnormalities and hepatic adverse events in the Maraviroc Clinical Development Programme [poster LBP7.9/1]. In: 11th European AIDS Conference/ EACS; 24-27 October 2007; Madrid, Spain.
-
(2007)
11th European AIDS Conference/ EACS
-
-
Hoepelman, I.M.1
Ayoub, A.2
Heera, J.3
-
47
-
-
58849120731
-
-
Lewis M, Simpson P, Fransen S, et al. CXCR4-using virus detected in patients receiving maraviroc in the phase III studies MOTIVATE 1 and 2 originates from a preexisting minority of CXCR4-using virus [abstract #56]. In: Program and Abstracts of the XVI HIV Drug Resistance Workshop; 12-16 June 2007; Barbados.
-
Lewis M, Simpson P, Fransen S, et al. CXCR4-using virus detected in patients receiving maraviroc in the phase III studies MOTIVATE 1 and 2 originates from a preexisting minority of CXCR4-using virus [abstract #56]. In: Program and Abstracts of the XVI HIV Drug Resistance Workshop; 12-16 June 2007; Barbados.
-
-
-
-
48
-
-
58849122951
-
-
van der Ryst E, Westby M. Changes in HIV-1 co-receptor tropism for patients participating in the maraviroc MOTIVATE 1 and 2 clinical trials [abstract #H- 715]. In: Program and Abstracts of the 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); 17-20 September 2007; Chicago, IL.
-
van der Ryst E, Westby M. Changes in HIV-1 co-receptor tropism for patients participating in the maraviroc MOTIVATE 1 and 2 clinical trials [abstract #H- 715]. In: Program and Abstracts of the 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); 17-20 September 2007; Chicago, IL.
-
-
-
-
49
-
-
55249099476
-
Changes in V3 loop sequence associated with failure of maraviroc treatment in patients enrolled in the MOTIVATE 1 and 2 trials
-
abstract #871, 3-6 February, Boston, MA
-
Lewis M, Mori J, Simpson P. Changes in V3 loop sequence associated with failure of maraviroc treatment in patients enrolled in the MOTIVATE 1 and 2 trials [abstract #871]. In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections
-
-
Lewis, M.1
Mori, J.2
Simpson, P.3
-
50
-
-
58849103730
-
-
Heera J, Saag M, Ive P, et al. Virological correlates associated with treatment failure at week 48 in the phase III study of maraviroc in treatment naïve patients [abstract #40LB]. In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
Heera J, Saag M, Ive P, et al. Virological correlates associated with treatment failure at week 48 in the phase III study of maraviroc in treatment naïve patients [abstract #40LB]. In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
-
-
-
51
-
-
52149101363
-
Vicriviroc, a next generation CCR5 antagonist, exhibits potent, sustained suppression of viral replication in treatment experienced adults: VICTOR-E1 48 week results
-
abstract #39LB, 3-6 February, Boston, MA
-
Zingman B, Suleiman J, DeJesus E, et al. Vicriviroc, a next generation CCR5 antagonist, exhibits potent, sustained suppression of viral replication in treatment experienced adults: VICTOR-E1 48 week results [abstract #39LB]. In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections
-
-
Zingman, B.1
Suleiman, J.2
DeJesus, E.3
-
52
-
-
54349114736
-
Maraviroc (MVC) pharmacokinetics (PK) in blood plasma (BP) genital tract (GT) fluid and tissue in health female volunteers
-
abstract #135LBJ, 3-6 February, Boston, MA
-
Dumond J, Patterson K, Pecha A, et al. Maraviroc (MVC) pharmacokinetics (PK) in blood plasma (BP) genital tract (GT) fluid and tissue in health female volunteers [abstract #135LBJ. In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections
-
-
Dumond, J.1
Patterson, K.2
Pecha, A.3
-
53
-
-
36849086108
-
Postexposure prophylaxis with a maraviroc-containing regimen after occupational exposure to a multiresistant HIV-infected source person
-
Méchai F, Quertainmont Y, Sahali S, et al. Postexposure prophylaxis with a maraviroc-containing regimen after occupational exposure to a multiresistant HIV-infected source person. J Med Virol 2008; 80:9-10.
-
(2008)
J Med Virol
, vol.80
, pp. 9-10
-
-
Méchai, F.1
Quertainmont, Y.2
Sahali, S.3
-
54
-
-
58849097831
-
The relationship of CCR5 inhibitors to CD4 cell count changes: A meta-analysis of recent clinical trials in treatment- experienced subjects
-
abstract #8000, 3-6 February, Boston, MA
-
Wilkin T, Ribaudo H, Gulick R. The relationship of CCR5 inhibitors to CD4 cell count changes: a meta-analysis of recent clinical trials in treatment- experienced subjects [abstract #8000], In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections
-
-
Wilkin, T.1
Ribaudo, H.2
Gulick, R.3
-
55
-
-
58849101943
-
Maravaroc, changes in CD4 and tropism in ART-Experienced 1029 Study [Poster P393]
-
12-16 November, Glasgow, Scotland
-
van De Ryst E, Meyer H, James M, et al. Maravaroc, changes in CD4 and tropism in ART-Experienced 1029 Study [Poster P393]. In: 8th International Conference on Drug Therapy in HIV Infection; 12-16 November 2006; Glasgow, Scotland.
-
(2006)
8th International Conference on Drug Therapy in HIV Infection
-
-
van De Ryst, E.1
Meyer, H.2
James, M.3
-
57
-
-
33751515147
-
Strategies for Management of Antiretroviral Therapy (SMART) Study Group. CD4+ count-guided interruption of antiretroviral treatment
-
El-Sadr WM, Lundgren JD, Neaton JD, et al., Strategies for Management of Antiretroviral Therapy (SMART) Study Group. CD4+ count-guided interruption of antiretroviral treatment. N Engl J Med 2006; 355:2283- 2296.
-
(2006)
N Engl J Med
, vol.355
, pp. 2283-2296
-
-
El-Sadr, W.M.1
Lundgren, J.D.2
Neaton, J.D.3
-
58
-
-
58849102824
-
-
Zolopa A, Andersen J, Komarow L, et al. Immediate vs. deferred ART in the setting of acute AIDS-related opportunistic infection: final results of a randomized strategy trial, ACTG A5164 [abstract #142], In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
Zolopa A, Andersen J, Komarow L, et al. Immediate vs. deferred ART in the setting of acute AIDS-related opportunistic infection: final results of a randomized strategy trial, ACTG A5164 [abstract #142], In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
-
-
-
59
-
-
56749174991
-
Safety and activity of SCH532706, a small molecule chemokine receptor 5 antagonist in HIV-1 infected individuals
-
abstract #38, 3-6 February, Boston, MA
-
Pett A, Emery S, MacRae K, et al. Safety and activity of SCH532706, a small molecule chemokine receptor 5 antagonist in HIV-1 infected individuals [abstract #38]. In: 15th Conference on Retroviruses and Opportunistic Infections; 3-6 February 2008; Boston, MA.
-
(2008)
15th Conference on Retroviruses and Opportunistic Infections
-
-
Pett, A.1
Emery, S.2
MacRae, K.3
-
60
-
-
9144236197
-
Antiretroviral activity of theanti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1
-
Kuritzkes DR, Jacobson J, Powderly WG, et al. Antiretroviral activity of theanti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1. J Infect Dis 2004; 189:286-291.
-
(2004)
J Infect Dis
, vol.189
, pp. 286-291
-
-
Kuritzkes, D.R.1
Jacobson, J.2
Powderly, W.G.3
-
61
-
-
33845975739
-
TNX-355 in combination with OBR, achieves statistically significant viral load reduction and CD4 cell increase when compared with OBR alone in phase II study at 48 weeks
-
abstract #THLB0218, 13-18 August, Toronto, ON
-
Norris D, Morales J, Godofsky E, et al. TNX-355 in combination with OBR, achieves statistically significant viral load reduction and CD4 cell increase when compared with OBR alone in phase II study at 48 weeks [abstract #THLB0218], In: XVI International AIDS Conference; 13-18 August 2006; Toronto, ON.
-
(2006)
XVI International AIDS Conference
-
-
Norris, D.1
Morales, J.2
Godofsky, E.3
-
62
-
-
58849092016
-
TNX-355 is active against enfuviritide resistanct HIV-1
-
abstract #THLB0024, 13-18 August, Toronto, ON
-
Weinheimer S, D'arigo K, Fung M, et al. TNX-355 is active against enfuviritide resistanct HIV-1 [abstract #THLB0024]. In: XVI International AIDS Conference; 13-18 August 2006; Toronto, ON.
-
(2006)
XVI International AIDS Conference
-
-
Weinheimer, S.1
D'arigo, K.2
Fung, M.3
-
63
-
-
0007473604
-
Potency, breadth and durability of the antiviral activity of PRO 140, a novel inhibitor of CCR5-mediated HIV-1 entry
-
abstract #667, 30 January-2 February, San Francisco, CA
-
Olson W, Ketas T, Nagashima K, et al. Potency, breadth and durability of the antiviral activity of PRO 140, a novel inhibitor of CCR5-mediated HIV-1 entry [abstract #667]. In: 7th Conference on Retroviruses and Opportunistic Infections; 30 January-2 February 2000; San Francisco, CA.
-
(2000)
7th Conference on Retroviruses and Opportunistic Infections
-
-
Olson, W.1
Ketas, T.2
Nagashima, K.3
-
64
-
-
52149087869
-
Antiviral effects and tolerability of the CCR5 monocloncal antibody PRO140: A proof of concept study in HIV infected individuals
-
abstract #WESS201, 22-25 July, Sydney, Australia
-
Saag MS, Jacobson JM, Thompson M, et al. Antiviral effects and tolerability of the CCR5 monocloncal antibody PRO140: a proof of concept study in HIV infected individuals [abstract #WESS201]. In: 4th IAS Conference on HIV Pathogenesis, Treatment and Prevention; 22-25 July 2007; Sydney, Australia.
-
(2007)
4th IAS Conference on HIV Pathogenesis, Treatment and Prevention
-
-
Saag, M.S.1
Jacobson, J.M.2
Thompson, M.3
-
65
-
-
59749092344
-
Petent antiretroviral activity of once-daily CCR5 antagonist INCB009471 over 14 days monotherapy
-
abstract #TUAB106, Sydney, Australia
-
Cohen C, DeJesus E, Mills A, et al. Petent antiretroviral activity of once-daily CCR5 antagonist INCB009471 over 14 days monotherapy [abstract #TUAB106]. In: XV International AIDS Conference; 2007; Sydney, Australia.
-
(2007)
XV International AIDS Conference
-
-
Cohen, C.1
DeJesus, E.2
Mills, A.3
-
66
-
-
40549092975
-
Safety, pharmacokinetics, and antiviral activity of HGS004, a novel fully human lgG4 monoclonal antibody against CCR5, in HIV-1-infected patients
-
Lalezari J, Yadavalli GK, Para M, et al. Safety, pharmacokinetics, and antiviral activity of HGS004, a novel fully human lgG4 monoclonal antibody against CCR5, in HIV-1-infected patients. J Infect Dis 2008; 197:721-727.
-
(2008)
J Infect Dis
, vol.197
, pp. 721-727
-
-
Lalezari, J.1
Yadavalli, G.K.2
Para, M.3
-
67
-
-
33444474896
-
TAK-652, a novel small molecule CCR5 antagonist with potent antiHIV-1 activity
-
abstract #541, 22-25 February, Boston, MA
-
Baba M, Kanzaki N, Miyake H, et al. TAK-652, a novel small molecule CCR5 antagonist with potent antiHIV-1 activity [abstract #541]. In: 12th Conference on Retroviruses and Opportunistic Infections; 22-25 February 2005; Boston, MA.
-
(2005)
12th Conference on Retroviruses and Opportunistic Infections
-
-
Baba, M.1
Kanzaki, N.2
Miyake, H.3
-
68
-
-
33444465511
-
TAK-652, a novel small molecule CCR5 antagonist has favourable anti-HIV interactions with other antiretrovirals in vitro
-
abstract #542, 22-25 February, Boston, MA
-
Tremblay C, Giguel F, Chou T, et al. TAK-652, a novel small molecule CCR5 antagonist has favourable anti-HIV interactions with other antiretrovirals in vitro [abstract #542]. In: 12th Conference on Retroviruses and Opportunistic Infections; 22-25 February 2005; Boston, MA.
-
(2005)
12th Conference on Retroviruses and Opportunistic Infections
-
-
Tremblay, C.1
Giguel, F.2
Chou, T.3
-
69
-
-
35548949608
-
Proof of concept of antiretroviral aotivity of AMD11070 (an orally administered CXCR4 entry inhibitor): Results of the first dosing cohort A studied in ACTG Protocol A5210
-
abstract #512, 25-28 February, Los Angeles, CA
-
Saag M, Rosenkranz S, Becker S, et al. Proof of concept of antiretroviral aotivity of AMD11070 (an orally administered CXCR4 entry inhibitor): results of the first dosing cohort A studied in ACTG Protocol A5210 [abstract #512]. In: 14th Conference on Retroviruses and Opportunistic Infections; 25-28 February 2007; Los Angeles, CA.
-
(2007)
14th Conference on Retroviruses and Opportunistic Infections
-
-
Saag, M.1
Rosenkranz, S.2
Becker, S.3
-
70
-
-
35548963010
-
CXCR4 antagonism: Proof of activity with AMD11070
-
abstract #511, 25-28 February, Los Angeles, CA
-
Moyle G, DeJesus E, Boffito M, et al. CXCR4 antagonism: proof of activity with AMD11070 [abstract #511]. In: 14th Conference on Retroviruses and Opportunistic Infections; 25-28 February 2007; Los Angeles, CA.
-
(2007)
14th Conference on Retroviruses and Opportunistic Infections
-
-
Moyle, G.1
DeJesus, E.2
Boffito, M.3
-
71
-
-
4644227515
-
Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection
-
Hendrix CW, Collier AC, Lederman MM, et al. Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection. Acquir Immune Defic Syndr 2004; 37:1253-1262.
-
(2004)
Acquir Immune Defic Syndr
, vol.37
, pp. 1253-1262
-
-
Hendrix, C.W.1
Collier, A.C.2
Lederman, M.M.3
-
72
-
-
45549093277
-
Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor
-
He Y, Xiao Y, Song H, et al. Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor. J Biol Chem 2008; 283:11126-11134.
-
(2008)
J Biol Chem
, vol.283
, pp. 11126-11134
-
-
He, Y.1
Xiao, Y.2
Song, H.3
|