메뉴 건너뛰기




Volumn 19, Issue 1, 2009, Pages 6-13

Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia

Author keywords

Association study; Glutamic acid decarboxylase 2 gene; Glutamine synthetase gene; Haplotype; Linkage disequilibrium; Multifactor dimensionality reduction; Schizophrenia; Single nucleotide polymorphism

Indexed keywords

GLUTAMATE AMMONIA LIGASE; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 2; GLUTAMATE RECEPTOR 2; GLUTAMATE RECEPTOR 3; GLUTAMATE RECEPTOR 4; GLUTAMATE RECEPTOR 5; UNCLASSIFIED DRUG;

EID: 58849103423     PISSN: 09558829     EISSN: None     Source Type: Journal    
DOI: 10.1097/YPG.0b013e328311875d     Document Type: Article
Times cited : (8)

References (38)
  • 1
    • 21244501298 scopus 로고    scopus 로고
    • GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss
    • Addington AM, Gornick M, Duckworth J, Sporn A, Gogtay N, Bobb A, et al. (2005). GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss, Mot Psychiatry 10:581-588.
    • (2005) Mot Psychiatry , vol.10 , pp. 581-588
    • Addington, A.M.1    Gornick, M.2    Duckworth, J.3    Sporn, A.4    Gogtay, N.5    Bobb, A.6
  • 2
    • 33747872904 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders
    • Akbarian S, Huang HS (2006). Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders. Brain Res Rev 52:293-304.
    • (2006) Brain Res Rev , vol.52 , pp. 293-304
    • Akbarian, S.1    Huang, H.S.2
  • 3
    • 0035829361 scopus 로고    scopus 로고
    • Controlling the false discovery rate in behavior genetics research
    • Benjamini Y, Drai D, Elmer G, Kafkafi N, Golani I (2001). Controlling the false discovery rate in behavior genetics research. Behav Brain Res 125: 279-284.
    • (2001) Behav Brain Res , vol.125 , pp. 279-284
    • Benjamini, Y.1    Drai, D.2    Elmer, G.3    Kafkafi, N.4    Golani, I.5
  • 6
    • 12944287763 scopus 로고    scopus 로고
    • Association study of polymorphisms in the excitatory amino acid transporter 2 gene (SLC1A2) with schizophrenia
    • Deng X, Shibata H, Ninomiya H, Tashiro N, Iwata N, Ozaki N, et al. (2004). Association study of polymorphisms in the excitatory amino acid transporter 2 gene (SLC1A2) with schizophrenia. BMC Psychiatry 4:21.
    • (2004) BMC Psychiatry , vol.4 , pp. 21
    • Deng, X.1    Shibata, H.2    Ninomiya, H.3    Tashiro, N.4    Iwata, N.5    Ozaki, N.6
  • 7
    • 34247326403 scopus 로고    scopus 로고
    • Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia
    • Deng X, Shibata H, Takeuchi N, Rachi S, Sakai M, Ninomiya H, et al. (2007). Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia. Am J Med Genet B Neuropsychiatr Genet 144:271-278.
    • (2007) Am J Med Genet B Neuropsychiatr Genet , vol.144 , pp. 271-278
    • Deng, X.1    Shibata, H.2    Takeuchi, N.3    Rachi, S.4    Sakai, M.5    Ninomiya, H.6
  • 8
    • 48649105703 scopus 로고    scopus 로고
    • Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia
    • Deng X, Sagata N, Takeuchi N, Tnaka M, Ninomiya H, Iwata N, et al. (2008). Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia. BMC Psychiatry 8:58.
    • (2008) BMC Psychiatry , vol.8 , pp. 58
    • Deng, X.1    Sagata, N.2    Takeuchi, N.3    Tnaka, M.4    Ninomiya, H.5    Iwata, N.6
  • 9
    • 2342471419 scopus 로고    scopus 로고
    • GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia
    • Dracheva S, Elhakem SL, McGurk SR, Davis KL, Haroutunian V (2004). GAD67 and GAD65 mRNA and protein expression in cerebrocortical regions of elderly patients with schizophrenia. J Neurosci Res 76:581-592.
    • (2004) J Neurosci Res , vol.76 , pp. 581-592
    • Dracheva, S.1    Elhakem, S.L.2    McGurk, S.R.3    Davis, K.L.4    Haroutunian, V.5
  • 10
    • 12444314603 scopus 로고    scopus 로고
    • Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia
    • Fujii Y, Shibata H, Kikuta R, Makino C, Tani A, Hirata N, et al. (2003). Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia. Psychiatr Genet 13:71-76.
    • (2003) Psychiatr Genet , vol.13 , pp. 71-76
    • Fujii, Y.1    Shibata, H.2    Kikuta, R.3    Makino, C.4    Tani, A.5    Hirata, N.6
  • 11
    • 0033914752 scopus 로고    scopus 로고
    • lonotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: Effects of schizophrenia
    • Gao XM, Sakai K, Roberts RC, Conley RR, Dean B, Tamminga CA (2000). lonotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. Am J Psychiatry 157:1141-1149.
    • (2000) Am J Psychiatry , vol.157 , pp. 1141-1149
    • Gao, X.M.1    Sakai, K.2    Roberts, R.C.3    Conley, R.R.4    Dean, B.5    Tamminga, C.A.6
  • 12
    • 0036307527 scopus 로고    scopus 로고
    • Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients
    • Gluck MR, Thomas RG, Davis KL, Haroutunian V (2002). Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. Am J Psychiatry 159:1165-1173.
    • (2002) Am J Psychiatry , vol.159 , pp. 1165-1173
    • Gluck, M.R.1    Thomas, R.G.2    Davis, K.L.3    Haroutunian, V.4
  • 13
    • 0037433052 scopus 로고    scopus 로고
    • Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions
    • Hahn LW, Ritchie MD, Moore JH (2003). Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions. Bioinformatics 19:376-382.
    • (2003) Bioinformatics , vol.19 , pp. 376-382
    • Hahn, L.W.1    Ritchie, M.D.2    Moore, J.H.3
  • 14
    • 4344614806 scopus 로고    scopus 로고
    • Prepulse inhibition deficits in GAD65 knockout mice and the effect of antipsychotic treatment
    • Heldt SA, Green A, Ressler KJ (2004). Prepulse inhibition deficits in GAD65 knockout mice and the effect of antipsychotic treatment. Neuropsychophar-macology 29:1610-1619.
    • (2004) Neuropsychophar-macology , vol.29 , pp. 1610-1619
    • Heldt, S.A.1    Green, A.2    Ressler, K.J.3
  • 15
    • 33847302424 scopus 로고    scopus 로고
    • No association between the glutamate decarboxylase 67 gene (GAD1) and schizophrenia in the Japanese population
    • Ikeda M, Ozaki N, Yamanouchi Y, Suzuki T, Kitajima T, Kinoshita Y, et al. (2007). No association between the glutamate decarboxylase 67 gene (GAD1) and schizophrenia in the Japanese population. Schizophr Res 91:22-26.
    • (2007) Schizophr Res , vol.91 , pp. 22-26
    • Ikeda, M.1    Ozaki, N.2    Yamanouchi, Y.3    Suzuki, T.4    Kitajima, T.5    Kinoshita, Y.6
  • 16
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt DC, Zukin SR (1991). Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry 148:1301-1308.
    • (1991) Am J Psychiatry , vol.148 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 17
    • 0035112644 scopus 로고    scopus 로고
    • Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): Analysis of association with schizophrenia
    • Joo A, Shibata H, Ninomiya H, Kawasaki H, Tashiro N, Fukumaki Y (2001). Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): analysis of association with schizophrenia. Mol Psychiatry 6:186-192.
    • (2001) Mol Psychiatry , vol.6 , pp. 186-192
    • Joo, A.1    Shibata, H.2    Ninomiya, H.3    Kawasaki, H.4    Tashiro, N.5    Fukumaki, Y.6
  • 18
    • 0026080111 scopus 로고
    • A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies
    • Lahiri DK, Nurnberger Jl Jr (1991). A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res 19:5444.
    • (1991) Nucleic Acids Res , vol.19 , pp. 5444
    • Lahiri, D.K.1    Nurnberger Jr, J.2
  • 20
    • 20244366232 scopus 로고    scopus 로고
    • Mutational screening and association study of glutamate decarboxylase 1 as a candidate susceptibility gene for bipolar affective disorder and schizophrenia
    • Lundorf MD, Buttenschon HN, Foldager L, Blackwood DH, Muir WJ, Murray V, et al. (2005). Mutational screening and association study of glutamate decarboxylase 1 as a candidate susceptibility gene for bipolar affective disorder and schizophrenia. Am J Med Genet B Neuropsychiatr Genet 135:94-101.
    • (2005) Am J Med Genet B Neuropsychiatr Genet , vol.135 , pp. 94-101
    • Lundorf, M.D.1    Buttenschon, H.N.2    Foldager, L.3    Blackwood, D.H.4    Muir, W.J.5    Murray, V.6
  • 21
    • 0042178301 scopus 로고    scopus 로고
    • Positive association of the AMPA receptor subunit GluR4 gene (GRIA4) haplotype with schizophrenia: Linkage disequilibrium mapping using SNPs evenly distributed across the gene region
    • Makino C, Fujii Y, Kikuta R, Hirata N, Tani A, Shibata A, et al. (2003). Positive association of the AMPA receptor subunit GluR4 gene (GRIA4) haplotype with schizophrenia: linkage disequilibrium mapping using SNPs evenly distributed across the gene region. Am J Med Genet B Neuropsychiatr Genet 116:17-22.
    • (2003) Am J Med Genet B Neuropsychiatr Genet , vol.116 , pp. 17-22
    • Makino, C.1    Fujii, Y.2    Kikuta, R.3    Hirata, N.4    Tani, A.5    Shibata, A.6
  • 22
    • 24144489818 scopus 로고    scopus 로고
    • Identification of single-nucleotide polymorphisms in the human W-methyl-D-aspartate receptor subunit NR2D gene, GRIN2D, and association study with schizophrenia
    • Makino C, Shibata H, Ninomiya H, Tashiro N, Fukumaki Y (2005). Identification of single-nucleotide polymorphisms in the human W-methyl-D-aspartate receptor subunit NR2D gene, GRIN2D, and association study with schizophrenia, Psychiatr Genet 15:215-221.
    • (2005) Psychiatr Genet , vol.15 , pp. 215-221
    • Makino, C.1    Shibata, H.2    Ninomiya, H.3    Tashiro, N.4    Fukumaki, Y.5
  • 23
  • 24
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn AR, Gainetdinov RR, Caron MG, Koller BH (1999). Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98:427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 25
    • 0034890791 scopus 로고    scopus 로고
    • The power of genome-wide association studies of complex disease genes: Statistical limitations of indirect approaches using SNP markers
    • Ohashi J, Tokunaga K (2001). The power of genome-wide association studies of complex disease genes: statistical limitations of indirect approaches using SNP markers. J Hum Genet 46:478-482.
    • (2001) J Hum Genet , vol.46 , pp. 478-482
    • Ohashi, J.1    Tokunaga, K.2
  • 26
    • 0034973569 scopus 로고    scopus 로고
    • Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
    • Ritchie MD, Hahn LW, Roodi N, Bailey LR, Dupont WD, Pari FF, et al. (2001). Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet 69:138-147.
    • (2001) Am J Hum Genet , vol.69 , pp. 138-147
    • Ritchie, M.D.1    Hahn, L.W.2    Roodi, N.3    Bailey, L.R.4    Dupont, W.D.5    Pari, F.F.6
  • 28
    • 0034779896 scopus 로고    scopus 로고
    • Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia
    • Shibata H, Joo A, Fujii Y, Tani A, Makino C, Hirata N, et al. (2001). Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia. Psychiatr Genet 11:139-144.
    • (2001) Psychiatr Genet , vol.11 , pp. 139-144
    • Shibata, H.1    Joo, A.2    Fujii, Y.3    Tani, A.4    Makino, C.5    Hirata, N.6
  • 29
    • 0037114827 scopus 로고    scopus 로고
    • Association study of polymorphisms in the GluR6 kainate receptor gene (GRIK2) with schizophrenia
    • Shibata H, Shibata A, Ninomiya H, Tashiro N, Fukumaki Y (2002). Association study of polymorphisms in the GluR6 kainate receptor gene (GRIK2) with schizophrenia. Psychiatry Res 113:59-67.
    • (2002) Psychiatry Res , vol.11 , Issue.3 , pp. 59-67
    • Shibata, H.1    Shibata, A.2    Ninomiya, H.3    Tashiro, N.4    Fukumaki, Y.5
  • 30
    • 29444438199 scopus 로고    scopus 로고
    • Association study of polymorphisms in the GluR7, KA1 and KA2 kainate receptor genes (GRIK3, GRIK4, GRIK5) with schizophrenia
    • Shibata H, Aramaki T, Sakai M, Ninomiya H, Tashiro N, Iwata N, et al. (2006). Association study of polymorphisms in the GluR7, KA1 and KA2 kainate receptor genes (GRIK3, GRIK4, GRIK5) with schizophrenia. Psychiatry Res 141:39-51.
    • (2006) Psychiatry Res , vol.141 , pp. 39-51
    • Shibata, H.1    Aramaki, T.2    Sakai, M.3    Ninomiya, H.4    Tashiro, N.5    Iwata, N.6
  • 31
    • 64649098447 scopus 로고    scopus 로고
    • Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia
    • In press
    • Shibata H, Tani A, Chikuhara T, Kikuta R, Sakai M, Ninomiya H, et al. (2008). Association study of polymorphisms in the group III metabotropic glutamate receptor genes, GRM4 and GRM7, with schizophrenia Psychiatric Res (In press).
    • (2008) Psychiatric Res
    • Shibata, H.1    Tani, A.2    Chikuhara, T.3    Kikuta, R.4    Sakai, M.5    Ninomiya, H.6
  • 32
    • 34548303921 scopus 로고    scopus 로고
    • Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression
    • Straub RE, Lipska BK, Egan MF, Goldberg TE, Callicott JH, Mayhew MB, et al. (2007). Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression. Mol Psychiatry 12:854-869.
    • (2007) Mol Psychiatry , vol.12 , pp. 854-869
    • Straub, R.E.1    Lipska, B.K.2    Egan, M.F.3    Goldberg, T.E.4    Callicott, J.H.5    Mayhew, M.B.6
  • 34
    • 0036842371 scopus 로고    scopus 로고
    • Polymorphism analysis of the upstream region of the human N-methyl-D- aspartate receptor subunit NR1 gene (GRIND: Implications for schizophrenia
    • Tani A, Kikuta R, Itoh K, Joo A, Shibata H, Ninomiya H, et al. (2002). Polymorphism analysis of the upstream region of the human N-methyl-D- aspartate receptor subunit NR1 gene (GRIND: implications for schizophrenia. Schizophr Res 58:83-86.
    • (2002) Schizophr Res , vol.58 , pp. 83-86
    • Tani, A.1    Kikuta, R.2    Itoh, K.3    Joo, A.4    Shibata, H.5    Ninomiya, H.6
  • 35
    • 0001200144 scopus 로고
    • Testing linkage disequilibrium between a disease gene and marker loci
    • Xie X, Ott J (1993). Testing linkage disequilibrium between a disease gene and marker loci. Am J Hum Genet 53:1107.
    • (1993) Am J Hum Genet , vol.53 , pp. 1107
    • Xie, X.1    Ott, J.2
  • 36
    • 0036850510 scopus 로고    scopus 로고
    • Selective alterations in ionotropic glutamate receptors in the anterior cingulate cortex in schizophrenia
    • Zavitsanou K, Ward PB, Huang XF (2002). Selective alterations in ionotropic glutamate receptors in the anterior cingulate cortex in schizophrenia. Neuropsychopharmacology 27:826-833.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 826-833
    • Zavitsanou, K.1    Ward, P.B.2    Huang, X.F.3
  • 37
    • 11844297386 scopus 로고    scopus 로고
    • An association study between polymorphisms in five genes in glutamate and GABA pathway and paranoid schizophrenia
    • Zhang B, Yuan Y, Jia Y, Yu X, Xu Q, Shen Y, et al. (2005). An association study between polymorphisms in five genes in glutamate and GABA pathway and paranoid schizophrenia. Eur Psychiatry 20:45-49.
    • (2005) Eur Psychiatry , vol.20 , pp. 45-49
    • Zhang, B.1    Yuan, Y.2    Jia, Y.3    Yu, X.4    Xu, Q.5    Shen, Y.6
  • 38
    • 34249341163 scopus 로고    scopus 로고
    • Systematic study of association of four GABAergic genes: Glutamic acid decarboxylase 1 gene, glutamic acid decarboxylase 2 gene, GABA(B) receptor 1 gene and GABA(A) receptor subunit beta2 gene, with schizophrenia using a universal DNA microarray
    • Zhao X, Qin S, Shi Y, Zhang A, Zhang J, Bian L, et al. (2007). Systematic study of association of four GABAergic genes: glutamic acid decarboxylase 1 gene, glutamic acid decarboxylase 2 gene, GABA(B) receptor 1 gene and GABA(A) receptor subunit beta2 gene, with schizophrenia using a universal DNA microarray. Schizophr Res 93:374-384.
    • (2007) Schizophr Res , vol.93 , pp. 374-384
    • Zhao, X.1    Qin, S.2    Shi, Y.3    Zhang, A.4    Zhang, J.5    Bian, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.