메뉴 건너뛰기




Volumn 49, Issue 1, 2009, Pages 199-207

Growth hormone-releasing peptide ghrelin inhibits homocysteine-induced endothelial dysfunction in porcine coronary arteries and human endothelial cells

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; BRADYKININ; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GHRELIN; HOMOCYSTEINE; LUCIGENIN; NITROPRUSSIDE SODIUM; SUPEROXIDE;

EID: 58749089263     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2008.08.065     Document Type: Article
Times cited : (40)

References (43)
  • 4
    • 0032499024 scopus 로고    scopus 로고
    • Homocysteine and atherothrombosis
    • Welch G.N., and Loscalzo J. Homocysteine and atherothrombosis. N Engl J Med 338 (1998) 1042-1050
    • (1998) N Engl J Med , vol.338 , pp. 1042-1050
    • Welch, G.N.1    Loscalzo, J.2
  • 5
    • 33947188045 scopus 로고    scopus 로고
    • Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells
    • Iantorno M., Chen H., Kim J.A., Tesauro M., Lauro D., and Cardillo C. Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cells. Am J Physiol Endocrinol Metab 292 (2007) E756-E764
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Iantorno, M.1    Chen, H.2    Kim, J.A.3    Tesauro, M.4    Lauro, D.5    Cardillo, C.6
  • 6
    • 2442419837 scopus 로고    scopus 로고
    • Ghrelin inhibits proinflammatory responses and nuclear factor-κB activation in human endothelial cells
    • Li W.G., Gavrila D., Liu X., Wang L., Gunnlaugsson S., Stoll L.L., et al. Ghrelin inhibits proinflammatory responses and nuclear factor-κB activation in human endothelial cells. Circulation 109 (2004) 2221-2226
    • (2004) Circulation , vol.109 , pp. 2221-2226
    • Li, W.G.1    Gavrila, D.2    Liu, X.3    Wang, L.4    Gunnlaugsson, S.5    Stoll, L.L.6
  • 7
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone releasing acylated peptide from stomach
    • Kojima M., Hosoda H., DateY N.M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone releasing acylated peptide from stomach. Nature 402 (1999) 656-660
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    DateY, N.M.3    Matsuo, H.4    Kangawa, K.5
  • 8
    • 58749101597 scopus 로고    scopus 로고
    • Cardiovascular Diseases. Heart Disease and Stroke Statistics-2005 Update, American Heart Association Accessed: Apr 22, 2008
    • Cardiovascular Diseases. Heart Disease and Stroke Statistics-2005 Update, American Heart Association. http://www.americanheart.org Accessed: Apr 22, 2008
  • 9
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-An inflammatory disease
    • Ross R. Atherosclerosis-An inflammatory disease. N Eng J Med 340 (1999) 115-126
    • (1999) N Eng J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 10
    • 0036350569 scopus 로고    scopus 로고
    • Homocysteine decreases endothelium-dependent vasorelaxation in porcine arteries
    • Chen C., Conklin B.S., Ren Z., and Zhong D. Homocysteine decreases endothelium-dependent vasorelaxation in porcine arteries. J Surg Res 102 (2002) 22-30
    • (2002) J Surg Res , vol.102 , pp. 22-30
    • Chen, C.1    Conklin, B.S.2    Ren, Z.3    Zhong, D.4
  • 11
    • 18844457413 scopus 로고    scopus 로고
    • Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries
    • Zhou W., Chai H., Lin P.H., Lumsden A.B., Yao Q., and Chen C. Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries. J Vasc Surg 41 (2005) 861-868
    • (2005) J Vasc Surg , vol.41 , pp. 861-868
    • Zhou, W.1    Chai, H.2    Lin, P.H.3    Lumsden, A.B.4    Yao, Q.5    Chen, C.6
  • 12
    • 20844460120 scopus 로고    scopus 로고
    • Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure
    • Nagaya N., Moriya J., Yasumara Y., Uematsu M., Ono F., Shimizu W., et al. Effects of ghrelin administration on left ventricular function, exercise capacity, and muscle wasting in patients with chronic heart failure. Circulation 110 (2004) 3674-3679
    • (2004) Circulation , vol.110 , pp. 3674-3679
    • Nagaya, N.1    Moriya, J.2    Yasumara, Y.3    Uematsu, M.4    Ono, F.5    Shimizu, W.6
  • 15
    • 0035908954 scopus 로고    scopus 로고
    • Chronic administration of ghrelin improves left ventricular function and attenuates development of cardiac cachexia in rats with heart failure
    • Nagaya N., Uematsu M., Kojima M., Ikeda Y., Yoshihara F., Shimizu W., et al. Chronic administration of ghrelin improves left ventricular function and attenuates development of cardiac cachexia in rats with heart failure. Circulation 104 (2001) 1430-1435
    • (2001) Circulation , vol.104 , pp. 1430-1435
    • Nagaya, N.1    Uematsu, M.2    Kojima, M.3    Ikeda, Y.4    Yoshihara, F.5    Shimizu, W.6
  • 16
    • 43549099785 scopus 로고    scopus 로고
    • The impact of obesity on cardiovascular disease risk factors and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis
    • Burke G.L., Bertoni A.G., Shea S., Tracy R., Watson K.E., Blumenthal R.S., et al. The impact of obesity on cardiovascular disease risk factors and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis. Arch Intern Med 168 (2008) 928-935
    • (2008) Arch Intern Med , vol.168 , pp. 928-935
    • Burke, G.L.1    Bertoni, A.G.2    Shea, S.3    Tracy, R.4    Watson, K.E.5    Blumenthal, R.S.6
  • 18
    • 27144468685 scopus 로고    scopus 로고
    • Developments in ghrelin biology and potential clinical relevance
    • Smith R.G., Jiang H., and Sun Y. Developments in ghrelin biology and potential clinical relevance. Trends Endocrinol Metab 16 (2005) 436-442
    • (2005) Trends Endocrinol Metab , vol.16 , pp. 436-442
    • Smith, R.G.1    Jiang, H.2    Sun, Y.3
  • 19
    • 0141923119 scopus 로고    scopus 로고
    • Cardiovascular and hormonal effects of subcutaneous administration of ghrelin, a novel growth hormone-releasing peptide, in healthy humans
    • Enomoto M., Nagaya N., Uematsu M., Okumura H., Nakagawa E., Ono F., et al. Cardiovascular and hormonal effects of subcutaneous administration of ghrelin, a novel growth hormone-releasing peptide, in healthy humans. Clin Sci 105 (2003) 431-435
    • (2003) Clin Sci , vol.105 , pp. 431-435
    • Enomoto, M.1    Nagaya, N.2    Uematsu, M.3    Okumura, H.4    Nakagawa, E.5    Ono, F.6
  • 20
    • 0037384111 scopus 로고    scopus 로고
    • Ghrelin improves left ventricular dysfunction and cardiac cachexia in heart failure
    • Nagaya N., and Kangawa K. Ghrelin improves left ventricular dysfunction and cardiac cachexia in heart failure. Curr Opin Pharmacol 3 (2003) 146-151
    • (2003) Curr Opin Pharmacol , vol.3 , pp. 146-151
    • Nagaya, N.1    Kangawa, K.2
  • 22
    • 36048932393 scopus 로고    scopus 로고
    • Clinical significance of ghrelin concentration of plasma and tumor tissue in patients with gastric cancer
    • An J.Y., Choi M.G., Noh J.H., Sohn T.S., Jin D.K., and Kim S. Clinical significance of ghrelin concentration of plasma and tumor tissue in patients with gastric cancer. J Surg Res 143 (2007) 344-349
    • (2007) J Surg Res , vol.143 , pp. 344-349
    • An, J.Y.1    Choi, M.G.2    Noh, J.H.3    Sohn, T.S.4    Jin, D.K.5    Kim, S.6
  • 23
    • 3242749843 scopus 로고    scopus 로고
    • Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells
    • Dixit V.D., Schaffer E.M., Pyle R.S., Collins G.D., Sakthivel S.K., Palaniappan R., et al. Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells. J Clin Invest 114 (2004) 57-66
    • (2004) J Clin Invest , vol.114 , pp. 57-66
    • Dixit, V.D.1    Schaffer, E.M.2    Pyle, R.S.3    Collins, G.D.4    Sakthivel, S.K.5    Palaniappan, R.6
  • 24
    • 48349103039 scopus 로고    scopus 로고
    • Ghrelin attenuates lipopolysaccharide-induced acute lung injury through no pathway
    • Chen J., Liu X., Shu Q., Li S., and Luo F. Ghrelin attenuates lipopolysaccharide-induced acute lung injury through no pathway. Med Sci Monit 14 (2008) BR141-BR146
    • (2008) Med Sci Monit , vol.14
    • Chen, J.1    Liu, X.2    Shu, Q.3    Li, S.4    Luo, F.5
  • 26
    • 18344368200 scopus 로고    scopus 로고
    • Adipocyte-derived cytokine resistin causes endothelial dysfunction of porcine coronary arteries
    • Kougias P., Chai H., Lin P.H., Lumsden A.B., Yao Q., and Chen C. Adipocyte-derived cytokine resistin causes endothelial dysfunction of porcine coronary arteries. J Vasc Surg 41 (2005) 691-698
    • (2005) J Vasc Surg , vol.41 , pp. 691-698
    • Kougias, P.1    Chai, H.2    Lin, P.H.3    Lumsden, A.B.4    Yao, Q.5    Chen, C.6
  • 27
    • 0141835815 scopus 로고    scopus 로고
    • HIV Tat protein causes endothelial dysfunction in porcine coronary arteries
    • Paladugu R., Fu W., Conklin B.S., Lin P.H., Lumsden A.B., Yao Q., et al. HIV Tat protein causes endothelial dysfunction in porcine coronary arteries. J Vasc Surg 38; (2003) 549-555
    • (2003) J Vasc Surg , vol.38 , pp. 549-555
    • Paladugu, R.1    Fu, W.2    Conklin, B.S.3    Lin, P.H.4    Lumsden, A.B.5    Yao, Q.6
  • 28
    • 19344375240 scopus 로고    scopus 로고
    • Ginsenosides block HIV protease inhibitor ritonavir-induced vascular dysfunction of porcine coronary arteries
    • Chai H., Zhou Lin P.H., Lumsden A.B., Yao Q., and Chen C. Ginsenosides block HIV protease inhibitor ritonavir-induced vascular dysfunction of porcine coronary arteries. Am J Physiol Heart Circ Physiol 288 (2005) H2965-H2971
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Chai, H.1    Zhou Lin, P.H.2    Lumsden, A.B.3    Yao, Q.4    Chen, C.5
  • 29
    • 0028839539 scopus 로고
    • Role of endogenous bradykinin in human coronary vasomotor control
    • Groves P., Kurz S., Just H., and Drexler H. Role of endogenous bradykinin in human coronary vasomotor control. Circulation 92 (1995) 3424-3430
    • (1995) Circulation , vol.92 , pp. 3424-3430
    • Groves, P.1    Kurz, S.2    Just, H.3    Drexler, H.4
  • 30
    • 0037076794 scopus 로고    scopus 로고
    • Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function
    • Leeson C.P., Hingorani A.D., Mullen M.J., Jeerooburkhan K.N.M., and Cole T.J. Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function. Circ Res 90 (2002) 1153-1158
    • (2002) Circ Res , vol.90 , pp. 1153-1158
    • Leeson, C.P.1    Hingorani, A.D.2    Mullen, M.J.3    Jeerooburkhan, K.N.M.4    Cole, T.J.5
  • 31
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite the good, the bad, and ugly
    • Beckman J.S., and Koppenol W.H. Nitric oxide, superoxide, and peroxynitrite the good, the bad, and ugly. Am J Physiol 271 (1996) C1424-C1437
    • (1996) Am J Physiol , vol.271
    • Beckman, J.S.1    Koppenol, W.H.2
  • 32
    • 0023802768 scopus 로고
    • Superoxide as a signal for increase in intracellular pH
    • Shibanuma M., Kuroki T., and Nose K. Superoxide as a signal for increase in intracellular pH. J Cell Physiol 136 (1988) 379-383
    • (1988) J Cell Physiol , vol.136 , pp. 379-383
    • Shibanuma, M.1    Kuroki, T.2    Nose, K.3
  • 33
    • 0027269781 scopus 로고
    • 2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells AP-1 as secondary antioxidant-responsive factor
    • 2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells AP-1 as secondary antioxidant-responsive factor. Embo J 12 (1993) 2005-2015
    • (1993) Embo J , vol.12 , pp. 2005-2015
    • Meyer, M.1    Schreck, R.2    Baeuerle, P.A.3
  • 35
    • 13844298945 scopus 로고    scopus 로고
    • Tetrahydrobiopterin and eNOS dimer/monomer ratio-a clue to eNOS uncoupling in diabetes?
    • Bauersachs J., and Schafer A. Tetrahydrobiopterin and eNOS dimer/monomer ratio-a clue to eNOS uncoupling in diabetes?. Cardiovas Res 65 (2005) 768-769
    • (2005) Cardiovas Res , vol.65 , pp. 768-769
    • Bauersachs, J.1    Schafer, A.2
  • 36
    • 0035805555 scopus 로고    scopus 로고
    • Oxygen reduction by nitric-oxide synthases
    • Stuehr D., Pou S., and Rosen G.M. Oxygen reduction by nitric-oxide synthases. J Biol Chem 276 (2001) 14533-14536
    • (2001) J Biol Chem , vol.276 , pp. 14533-14536
    • Stuehr, D.1    Pou, S.2    Rosen, G.M.3
  • 37
    • 2942558814 scopus 로고    scopus 로고
    • Homocysteine induces oxidative stress by uncoupling of no synthase activity through reduction of tetrahydrobiopterin
    • Topal G., Brunet A., Millanvoye E., Boucher J., Rendu F., Devynck M., et al. Homocysteine induces oxidative stress by uncoupling of no synthase activity through reduction of tetrahydrobiopterin. Free Radic Biol Med 36 (2004) 1532-1541
    • (2004) Free Radic Biol Med , vol.36 , pp. 1532-1541
    • Topal, G.1    Brunet, A.2    Millanvoye, E.3    Boucher, J.4    Rendu, F.5    Devynck, M.6
  • 38
    • 0037784049 scopus 로고    scopus 로고
    • Ghrelin, a novel growth hormone-releasing peptide, in the treatment of chronic heart failure
    • Nagaya N., and Kangawa K. Ghrelin, a novel growth hormone-releasing peptide, in the treatment of chronic heart failure. Regul Pept 114 (2003) 71-77
    • (2003) Regul Pept 114 , pp. 71-77
    • Nagaya, N.1    Kangawa, K.2
  • 39
    • 33646805400 scopus 로고    scopus 로고
    • Effects of homocysteine and ginsenoside Rb1 on endothelial proliferation and superoxide anion production
    • Ohashi R., Yan S., Mu H., Chai H., Yao Q., Lin P.H., et al. Effects of homocysteine and ginsenoside Rb1 on endothelial proliferation and superoxide anion production. J Surg Res 133 (2006) 89-94
    • (2006) J Surg Res , vol.133 , pp. 89-94
    • Ohashi, R.1    Yan, S.2    Mu, H.3    Chai, H.4    Yao, Q.5    Lin, P.H.6
  • 40
    • 34547689728 scopus 로고    scopus 로고
    • Human immunodeficiency virus protease inhibitor ritonavir inhibits cholesterol efflux from human macrophage-derived foam cells
    • Wang X., Mu H., Chai H., Liao D., Yao Q., and Chen C. Human immunodeficiency virus protease inhibitor ritonavir inhibits cholesterol efflux from human macrophage-derived foam cells. Am J Pathol 171 (2007) 304-314
    • (2007) Am J Pathol , vol.171 , pp. 304-314
    • Wang, X.1    Mu, H.2    Chai, H.3    Liao, D.4    Yao, Q.5    Chen, C.6
  • 41
    • 47949094078 scopus 로고    scopus 로고
    • Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation
    • Xu X., Jhun B.S., Ha C.H., and Jin Z.G. Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation. Endocrinology 149 (2008) 4183-4192
    • (2008) Endocrinology , vol.149 , pp. 4183-4192
    • Xu, X.1    Jhun, B.S.2    Ha, C.H.3    Jin, Z.G.4
  • 42
    • 34548045763 scopus 로고    scopus 로고
    • Prevalence of hyperhomocysteinemia in vascular disease: comparative study of thrombotic venous disease vis-à-vis occlusive arterial disease
    • Bhargava S., Parakh R., Manocha A., Ali A., and Srivastava L.M. Prevalence of hyperhomocysteinemia in vascular disease: comparative study of thrombotic venous disease vis-à-vis occlusive arterial disease. Vascular 15 (2007) 149-153
    • (2007) Vascular , vol.15 , pp. 149-153
    • Bhargava, S.1    Parakh, R.2    Manocha, A.3    Ali, A.4    Srivastava, L.M.5
  • 43
    • 0036109544 scopus 로고    scopus 로고
    • Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system
    • Katugampola S.D., Maguire J.J., Kuc R.E., Wiley K.E., and Davenport A.P. Discovery of recently adopted orphan receptors for apelin, urotensin II, and ghrelin identified using novel radioligands and functional role in the human cardiovascular system. Can J Physiol Pharmacol 80 (2002) 369-374
    • (2002) Can J Physiol Pharmacol , vol.80 , pp. 369-374
    • Katugampola, S.D.1    Maguire, J.J.2    Kuc, R.E.3    Wiley, K.E.4    Davenport, A.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.