Clostridium difficile toxin A promotes dendritic cell maturation and chemokine CXCL2 expression through p38, IKK, and the NF-κB signaling pathway

Journal of Molecular Medicine

Volumn 87, Issue 2, 2009, Pages 169-180

  Lee, Jin Young ^a   Kim, Hyunah ^a   Cha, Mi Yeon ^a   Park, Hong Gyu ^a   Kim, Young Jeon ^b   Kim, In Young ^a   Kim, Jung Mogg ^a  

^a Hanyang University College of Medicine   (South Korea)

^b Joongbu University   (South Korea)

Author keywords

Clostridium difficile toxin A; CXCL2; Dendritic cells; Maturation; Mitogen activated protein kinase

Indexed keywords

CLOSTRIDIUM DIFFICILE TOXIN A; CXCL2 CHEMOKINE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVITY; KNOCKOUT MOUSE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BACTERIAL TOXINS; CELL DIFFERENTIATION; CELLS, CULTURED; CHEMOKINE CXCL2; CHEMOTAXIS, LEUKOCYTE; DENDRITIC CELLS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENTEROTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; I-KAPPA B KINASE; IMMUNOBLOTTING; IMMUNOPHENOTYPING; LUCIFERASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 58549112757     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-008-0415-2     Document Type: Article

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