-
1
-
-
38449100230
-
A protocol for designing siRNAs with high functionality and specificity
-
Birmingham,A., Anderson,E., Sullivan,K., Reynolds,A., Boese,Q., Leake,D., Karpilow,J. and Khvorova,A. (2007) A protocol for designing siRNAs with high functionality and specificity. Nat. Protoc., 2 2068-2078.
-
(2007)
Nat. Protoc
, vol.2
, pp. 2068-2078
-
-
Birmingham, A.1
Anderson, E.2
Sullivan, K.3
Reynolds, A.4
Boese, Q.5
Leake, D.6
Karpilow, J.7
Khvorova, A.8
-
2
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm,D., Streetz,K.L., Jopling,C.L., Storm,T.A., Pandey,K., Davis,C.R., Marion,P., Salazar,F. and Kay,M.A. (2006) Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature, 441, 537-541.
-
(2006)
Nature
, vol.441
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
Storm, T.A.4
Pandey, K.5
Davis, C.R.6
Marion, P.7
Salazar, F.8
Kay, M.A.9
-
3
-
-
33746782507
-
Generation of RNAi Libraries for High-Throughput Screens
-
Clark,J. and Ding,S. (2006) Generation of RNAi Libraries for High-Throughput Screens. J. Biomed. Biotechnol., 2006, 45716.
-
(2006)
J. Biomed. Biotechnol
, vol.2006
, pp. 45716
-
-
Clark, J.1
Ding, S.2
-
4
-
-
27944473306
-
Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency
-
Patzel,V., Rutz,S., Dietrich,I., Koberle,C., Scheffold,A. and Kaufmann,S.H. (2005) Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency. Nat. Biotechnol., 23, 1440-1444.
-
(2005)
Nat. Biotechnol
, vol.23
, pp. 1440-1444
-
-
Patzel, V.1
Rutz, S.2
Dietrich, I.3
Koberle, C.4
Scheffold, A.5
Kaufmann, S.H.6
-
5
-
-
30944440768
-
High-throughput screening of effective siRNAs from RNAi libraries delivered via bacterial invasion
-
Zhao,H.F., L'Abbe,D., Jolicoeur,N., Wu,M., Li,Z., Yu,Z. and Shen,S.H. (2005) High-throughput screening of effective siRNAs from RNAi libraries delivered via bacterial invasion. Nat. methods, 2, 967-973.
-
(2005)
Nat. methods
, vol.2
, pp. 967-973
-
-
Zhao, H.F.1
L'Abbe, D.2
Jolicoeur, N.3
Wu, M.4
Li, Z.5
Yu, Z.6
Shen, S.H.7
-
6
-
-
0142092529
-
High-throughput selection of effective RNAi probes for gene silencing
-
Kumar,R., Conklin,D.S. and Mittal,V. (2003) High-throughput selection of effective RNAi probes for gene silencing. Genome Res., 13, 2333-2340.
-
(2003)
Genome Res
, vol.13
, pp. 2333-2340
-
-
Kumar, R.1
Conklin, D.S.2
Mittal, V.3
-
7
-
-
0037162522
-
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
-
Yang,D., Buchholz,F., Huang,Z., Goga,A., Chen,C.Y., Brodsky,F.M. and Bishop,J.M. (2002) Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells. Proc. Natl Acad. Sci. USA, 99, 9942-9947.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 9942-9947
-
-
Yang, D.1
Buchholz, F.2
Huang, Z.3
Goga, A.4
Chen, C.Y.5
Brodsky, F.M.6
Bishop, J.M.7
-
8
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson,A.L., Bartz,S.R., Schelter,J., Kobayashi,S.V., Burchard,J., Mao,M., Li,B., Cavet,G. and Linsley,P.S. (2003) Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol., 21, 635-637.
-
(2003)
Nat. Biotechnol
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
9
-
-
13844281898
-
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
-
Kim,D.H., Behlke,M.A., Rose,S.D., Chang,M.S., Choi,S. and Rossi,J.J. (2005) Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat. Biotechnol., 23, 222-226.
-
(2005)
Nat. Biotechnol
, vol.23
, pp. 222-226
-
-
Kim, D.H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.S.4
Choi, S.5
Rossi, J.J.6
-
10
-
-
10444240021
-
A plasmid-based system for expressing small interfering RNA libraries in mammalian cells
-
Kaykas,A. and Moon,R.T. (2004) A plasmid-based system for expressing small interfering RNA libraries in mammalian cells. BMC Cell Biol. 5, 16.
-
(2004)
BMC Cell Biol
, vol.5
, pp. 16
-
-
Kaykas, A.1
Moon, R.T.2
-
11
-
-
0034660858
-
In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/ uracil phosphoribosyltransferase fusion gene
-
Erbs,P., Regulier,E., Kintz,J., Leroy,P., Poitevin,Y., Exinger,F., Jund,R. and Mehtali,M. (2000) In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/ uracil phosphoribosyltransferase fusion gene. Cancer Res., 60 3813-3822.
-
(2000)
Cancer Res
, vol.60
, pp. 3813-3822
-
-
Erbs, P.1
Regulier, E.2
Kintz, J.3
Leroy, P.4
Poitevin, Y.5
Exinger, F.6
Jund, R.7
Mehtali, M.8
-
12
-
-
0031721556
-
Functional gene transfer from intracellular bacteria to mammalian cells
-
Grillot-Courvalin,C., Goussard,S., Huctz,F., Ojcius,D.M. and Courvahn,P. (1998) Functional gene transfer from intracellular bacteria to mammalian cells. Nat. Biotechnol., 16, 862-866.
-
(1998)
Nat. Biotechnol
, vol.16
, pp. 862-866
-
-
Grillot-Courvalin, C.1
Goussard, S.2
Huctz, F.3
Ojcius, D.M.4
Courvahn, P.5
-
13
-
-
0345688213
-
Vaults: A ribonucleoprotein particle involved in drug resistance
-
Mossink,M.H., van Zon,A., Scheper,R.J., Sonneveld,P. and Wiemer,E.A. (2003) Vaults: A ribonucleoprotein particle involved in drug resistance. Oncogene, 22, 7458-7467.
-
(2003)
Oncogene
, vol.22
, pp. 7458-7467
-
-
Mossink, M.H.1
van Zon, A.2
Scheper, R.J.3
Sonneveld, P.4
Wiemer, E.A.5
-
14
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
Elbashir,S.M., Martinez,J., Patkaniowska,A., Lendeckel,W. and Tuschl,T. (2001) Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J., 20, 6877-6888.
-
(2001)
EMBO J
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
Martinez, J.2
Patkaniowska, A.3
Lendeckel, W.4
Tuschl, T.5
-
15
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir,S.M., Harborth,J., Lendeckel,W., Yalcin,A., Weber,K. and Tuschl,T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 411, 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
16
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir,S.M., Lendeckel,W. and Tuschl,T. (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev., 15, 188-200.
-
(2001)
Genes Dev
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
17
-
-
3242736704
-
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
-
Meister,G., Landthaler,M., Patkaniowska,A., Dorsett,Y., Teng,G. and Tuschl,T. (2004) Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell, 15, 185-197.
-
(2004)
Mol. Cell
, vol.15
, pp. 185-197
-
-
Meister, G.1
Landthaler, M.2
Patkaniowska, A.3
Dorsett, Y.4
Teng, G.5
Tuschl, T.6
-
18
-
-
36148972467
-
Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells
-
Vickers,T.A., Lima,W.F., Nichols,J.G. and Crooke,S.T. (2007) Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells. Nucleic Acids Res., 35, 6598-6610.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 6598-6610
-
-
Vickers, T.A.1
Lima, W.F.2
Nichols, J.G.3
Crooke, S.T.4
-
19
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds,A., Leake,D., Boese,Q., Scaringe,S., Marshall,W.S. and Khvorova,A. (2004) Rational siRNA design for RNA interference. Nat. Biotechnol., 22, 326-330.
-
(2004)
Nat. Biotechnol
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
20
-
-
33745608078
-
Off-target effects by siRNA can induce toxic phenotype
-
Fedorov,Y., Anderson,E.M., Birmingham,A., Reynolds,A., Karpilow,J., Robinson,K., Leake,D., Marshall,W.S. and Khvorova,A. (2006) Off-target effects by siRNA can induce toxic phenotype. RNA, 12, 1188-1196.
-
(2006)
RNA
, vol.12
, pp. 1188-1196
-
-
Fedorov, Y.1
Anderson, E.M.2
Birmingham, A.3
Reynolds, A.4
Karpilow, J.5
Robinson, K.6
Leake, D.7
Marshall, W.S.8
Khvorova, A.9
-
21
-
-
38649140462
-
Advances in MicroRNAs: Implications for gene therapists
-
Marquez,R.T. and McCaffrey,A.P. (2009) Advances in MicroRNAs: implications for gene therapists. Hum. Gene. Ther., 19, 27-37.
-
(2009)
Hum. Gene. Ther
, vol.19
, pp. 27-37
-
-
Marquez, R.T.1
McCaffrey, A.P.2
-
22
-
-
34548548614
-
Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC
-
Castanotto,D., Sakurai,K., Lingeman,R., Li,H., Shively,L., Aagaard,L., Soifer,H., Gatignol,A., Riggs,A. and Rossi,J.J. (2007) Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC. Nucleic Acids Res., 35, 5154-5164.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5154-5164
-
-
Castanotto, D.1
Sakurai, K.2
Lingeman, R.3
Li, H.4
Shively, L.5
Aagaard, L.6
Soifer, H.7
Gatignol, A.8
Riggs, A.9
Rossi, J.J.10
-
23
-
-
33745614074
-
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing
-
Jackson,A.L., Burchard,J., Leake,D., Reynolds,A., Schelter,J., Guo,J., Johnson,J.M., Lim,L., Karpilow,J., Nichols,K. et al. (2006) Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing. RNA, 12, 1197-1205.
-
(2006)
RNA
, vol.12
, pp. 1197-1205
-
-
Jackson, A.L.1
Burchard, J.2
Leake, D.3
Reynolds, A.4
Schelter, J.5
Guo, J.6
Johnson, J.M.7
Lim, L.8
Karpilow, J.9
Nichols, K.10
|