Synthesis and pharmacological evaluation of N- (dimethylamino)ethyl derivatives of benzo- and pyridopyridazinones

Archiv der Pharmazie

Volumn 342, Issue 1, 2009, Pages 41-47

  Pakulska, Wanda ^a   Malinowski, Zbigniew ^b   Szczesniak, Aleksandra K ^b   Czarnecka, Elzbieta ^a   Epsztajn, Jan ^b  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b UNIVERSITY OF LODZ   (Poland)

Author keywords

Hot plate test; Phthalazinones; Pyridopyridazinones; Tail flick test; Writhing test

Indexed keywords

2 [2 (DIMETHYLAMINO)ETHYL] 2H PHTHALAZIN 1 ONE; 2 [2 (DIMETHYLAMINO)ETHYL] 2H PYRIDAZIN 3 ONE; 2 [2 (DIMETHYLAMINO)ETHYL] 2H PYRIDO[3,4 D]PYRIDAZIN 1 ONE; 2 [2 (DIMETHYLAMINO)ETHYL] 4 METHYL 2H PHTHALAZIN 1 ONE; 2 [2 (DIMETHYLAMINO)ETHYL] 4 PHENYL 2H PHTHALAZIN 1 ONE; 2 [2 (DIMETHYLAMINO)ETHYL] 6 METHOXY 4 (2 METHOXYPHENYL) 2H PHTHALAZIN 1 ONE; 2 [2 (DIMETHYLAMINO)ETHYL] 6 METHOXY 4 (PYRIDIN 2 YL) 2H PHTHALAZIN 1 ONE; 2 [2 (DIMETHYLAMINO)ETHYL] 6 METHOXY 4 (PYRIDIN 3 YL) 2H PHTHALAZIN 1 ONE; 2 [2 (DIMETHYLAMINO)ETHYL] 6 METHOXY 4 (PYRIDIN 4 YL) 2H PHTHALAZIN 1 ONE; 7 [2 (DIMETHYLAMINO)ETHYL] 7H PYRIDO[2,3 D]PYRIDAZIN 8 ONE; ANALGESIC AGENT; BENZOPYRIDAZINONE DERIVATIVE; DIPYRONE; N (DIMETHYLAMINO)ETHYL DERIVATIVE; PYRIDOPYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; MOUSE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; TAIL FLICK TEST; WRITHING TEST;

ANALGESICS, NON-NARCOTIC; ANIMALS; DIPYRONE; DRUG EVALUATION, PRECLINICAL; MICE; PAIN THRESHOLD; PHTHALAZINES; PYRIDAZINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 58549097876     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200800016     Document Type: Article

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