4,5-Functionalized 6-phenyl-3(2H)-pyridazinones: Synthesis and evaluation of antinociceptive activity

European Journal of Medicinal Chemistry

Volumn 31, Issue 1, 1996, Pages 65-70

  Dal Piaz, V ^a   Giovannoni, M P ^a   Ciciani, G ^a   Barlocco, D ^b   Giardina, G ^c   Petrone, G ^c   Clarke, G D ^c  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c SmithKline Beecham   (Italy)

Author keywords

Antinociceptive activity; Emorfazone; Pyridazinone

Indexed keywords

4 AMINO 2 METHYL 6 PHENYL 5 VINYL 3(2H) PYRIDAZINONE; 5 ACETYL 2 METHYL 6 PHENYL 4 [[2 (4 PHENYL 1 PIPERAZINYL)ETHYL]AMINO] 3(2H) PIPERAZINONE; 5 ACETYL 4 AMINO 6 PHENYL 2 [(4 PHENYL 1 PIPERAZINYL)METHYL]PYRIDAZIN 3(2H) ONE; ACETYLSALICYLIC ACID; ANALGESIC AGENT; EMORFAZONE; PARACETAMOL; PYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; REACTION ANALYSIS; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030026892     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(96)80008-0     Document Type: Article

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