α1-Adrenoceptor antagonists. Rational design, synthesis and biological evaluation of new trazodone-like compounds

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 3, 2002, Pages 437-440

  Betti, Laura ^a   Botta, Maurizio ^b   Corelli, Federico ^b   Floridi, Monia ^c   Fossa, Paola ^d   Giannaccini, Gino ^a   Manetti, Fabrizio ^b   Strappaghetti, Giovannella ^c   Corsano, Stefano ^c  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BENZIMIDAZOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PYRIDAZINONE DERIVATIVE; TRAZODONE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; NONHUMAN; PHARMACOPHORE; RAT; STRUCTURE ACTIVITY RELATION;

ALKYLATION; ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BINDING, COMPETITIVE; CHEMISTRY, PHYSICAL; HYDANTOINS; MODELS, MOLECULAR; RADIOLIGAND ASSAY; RATS; RECEPTORS, ADRENERGIC, ALPHA-1; STRUCTURE-ACTIVITY RELATIONSHIP; TRAZODONE;

EID: 0037059926     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00772-7     Document Type: Article

References (11)