New 4-(4-methyl-phenyl)phthalazin-1(2H)-one derivatives and their effects on α1-receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 10, 2006, Pages 2575-2579

  Strappaghetti, Giovannella ^a   Brodi, Chiara ^a   Giannaccini, Gino ^b   Betti, Laura ^b  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

1 Adrenoceptor affinity; 2 Adrenoceptor affinity; 5HT1A serotoninergic affinity; Arylpiperazines; Phenyl phthalazinone fragment; Structure activity relationships (SAR)

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; PHTHALAZINE DERIVATIVE; PIPERAZINE DERIVATIVE; SEROTONIN 1A RECEPTOR;

ARTICLE; BINDING AFFINITY; DRUG DESIGN; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

PHTHALAZINES; RECEPTORS, ADRENERGIC, ALPHA-1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33646471371     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.02.068     Document Type: Article

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