Efficient one-pot synthesis of 1,3-disubstituted pyridin-2(1H)-ones from α-hydroxyketene S, S-acetals under Vilsmeier conditions

Synthesis

Volumn , Issue 22, 2008, Pages 3633-3638

  Liu, Jun ^a   Liang, Deqiang ^a   Wang, Mang ^a   Liu, Qun ^a  

^a NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

hydroxyketene S, S acetals; Pyridin 2(1H) ones; Vilsmeier reagent

Indexed keywords

REACTION KINETICS;

CARBAMOYL KETENES; CASCADE REACTIONS; DOMINO REACTIONS; ONE-POT SYNTHESIS; PYRIDIN-2(1H)-ONES; VILSMEIER REAGENT;

SALTS;

ACETAL DERIVATIVE; KETENE DERIVATIVE; PYRIDINE DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; INFRARED SPECTROSCOPY; ONE POT SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; VILSMEIER HAACK REACTION;

EID: 58549090819     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1083198     Document Type: Article

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36. 000 = 272, R1 = 0.0428, wR2 = 0.1077. CCDC 690433 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data- request/cif.