Genomic response of the rat brain to global ischemia and reperfusion

Brain Research

Volumn 1252, Issue , 2009, Pages 1-14

  Büttner, Fabian ^a   Cordes, Christian ^a   Gerlach, Frank ^b   Heimann, Axel ^a   Alessandri, Beat ^a   Luxemburger, Ulrich ^a   Türeci, Özlem ^a   Hankeln, Thomas ^a   Kempski, Oliver ^a   Burmester, Thorsten ^b  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Gene expression; Ischemia; Microarray; Quantitative PCR; Reperfusion; Stroke

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; HEAT SHOCK PROTEIN 70; PROSTAGLANDIN SYNTHASE; TRANSCRIPTION FACTOR; UBIDECARENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN TISSUE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOME; IMMUNE RESPONSE; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; BRAIN; BRAIN ISCHEMIA; CLUSTER ANALYSIS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, WISTAR; REPERFUSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

RATTUS;

EID: 58349100082     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.10.045     Document Type: Article

References (64)

1. Alfranca A., Gutierrez M.D., Vara A., Aragones J., Vidal F., and Landazuri M.O. c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription. Mol. Cell. Biol. 22 (2002) 12-22
2. Ashkar S., Weber G.F., Panoutsakopoulou V., Sanchirico M.E., Jansson M., Zawaideh S., Rittling S.R., Denhardt D.T., Glimcher M.J., and Cantor H. Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science 287 (2000) 860-864
3. Barone F.C., and Feuerstein G.Z. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J. Cereb. Blood Flow Metab. 19 (1999) 819-834
4. Beck Jr. G.R., Zerler B., and Moran E. Phosphate is a specific signal for induction of osteopontin gene expression. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 8352-8357
5. Brambrink A.M., Kopacz L., Astheimer A., Noga H., Heimann A., and Kempski O. Control of brain temperature during experimental global ischemia in rats. J. Neurosci. Methods 92 (1999) 111-122
6. Burmester T., Weich B., Reinhardt S., and Hankeln T. A vertebrate globin expressed in the brain. Nature 407 (2000) 520-523
7. Burmester T., Ebner B., Weich B., and Hankeln T. Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues. Mol. Biol. Evol. 19 (2002) 416-421
8. Burmester T., Gerlach F., and Hankeln T. Regulation and role of neuroglobin and cytoglobin under hypoxia. Adv. Exp. Med. Biol. 618 (2007) 169-180
9. Chen J., Nagayama T., Jin K., Stetler R.A., Zhu R.L., Graham S.H., and Simon R.P. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J. Neurosci. 18 (1998) 4914-4928
10. Concannon C.G., Gorman A.M., and Samali A. On the role of Hsp27 in regulating apoptosis. Apoptosis 8 (2003) 61-70
11. Copani A., Bruno V.M., Barresi V., Battaglia G., Condorelli D.F., and Nicoletti F. Activation of metabotropic glutamate receptors prevents neuronal apoptosis in culture. J. Neurochem. 64 (1995) 101-108
12. Danton G.H., and Dietrich W.D. Inflammatory mechanisms after ischemia and stroke. J. Neuropathol. Exp. Neurol. 62 (2003) 127-136
13. Dirnagl U., Thoren P., Villringer A., Sixt G., Them A., and Einhaupl K.M. Global forebrain ischaemia in the rat: controlled reduction of cerebral blood flow by hypobaric hypotension and two-vessel occlusion. Neurol. Res. 15 (1993) 128-130
14. Dirnagl U., Iadecola C., and Moskowitz M.A. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 22 (1999) 391-397
15. Doutheil J., Althausen S., Gissel C., and Paschen W. Activation of MYD116 (gadd34) expression following transient forebrain ischemia of rat: implications for a role of disturbances of endoplasmic reticulum calcium homeostasis. Brain Res. Mol. Brain Res. 63 (1999) 225-232
16. Eisen M.B., Spellman P.T., Brown P.O., and Botstein D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 14863-14868
17. Fujita T., Toda K., Karimova A., Yan S.F., Naka Y., Yet S.F., and Pinsky D.J. Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis. Nat. Med. 7 (2001) 598-604
18. Goetz D.H., Holmes M.A., Borregaard N., Bluhm M.E., Raymond K.N., and Strong R.K. The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. Mol. Cell 10 (2002) 1033-1043
19. Greenbaum L.E., Li W., Cressman D.E., Peng Y., Ciliberto G., Poli V., and Taub R. CCAAT enhancer-binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy. J. Clin. Invest. 102 (1998) 996-1007
20. Haddad G.G., and Jiang C. O2 deprivation in the central nervous system: on mechanisms of neuronal response, differential sensitivity and injury. Prog. Neurobiol. 40 (1993) 277-318
21. Hansen A.J. Effect of anoxia on ion distribution in the brain. Physiol. Rev. 65 (1985) 101-148
22. Heimann A., Kroppenstedt S., Ulrich P., and Kempski O.S. Cerebral blood flow autoregulation during hypobaric hypotension assessed by laser Doppler scanning. J. Cereb. Blood Flow Metab. 14 (1994) 1100-1105
23. Houry W.A. Chaperone-assisted protein folding in the cell cytoplasm. Curr. Protein Pept. Sci. 2 (2001) 227-244
24. Jin K., Mao X.O., Eshoo M.W., Nagayama T., Minami M., Simon R.P., and Greenberg D.A. Microarray analysis of hippocampal gene expression in global cerebral ischemia. Ann. Neurol. 50 (2001) 93-103
25. Kapadia R., Tureyen K., Bowen K.K., Kalluri H., Johnson P.F., and Vemuganti R. Decreased brain damage and curtailed inflammation in transcription factor CCAAT/enhancer binding protein beta knockout mice following transient focal cerebral ischemia. J. Neurochem. 98 (2006) 1718-1731
26. Kato H., Kogure K., Liu X.H., Araki T., and Itoyama Y. Progressive expression of immunomolecules on activated microglia and invading leukocytes following focal cerebral ischemia in the rat. Brain Res. 734 (1996) 203-212
27. Katsura K., Kristian T., and Siesjo B.K. Energy metabolism, ion homeostasis, and cell damage in the brain. Biochem. Soc. Trans. 22 (1994) 991-996
28. Kawahara N., Wang Y., Mukasa A., Furuya K., Shimizu T., Hamakubo T., Aburatani H., Kodama T., and Kirino T. Genome-wide gene expression analysis for induced ischemic tolerance and delayed neuronal death following transient global ischemia in rats. J. Cereb. Blood Flow Metab. 24 (2004) 212-223
29. Keyvani K., Witte O.W., and Paulus W. Gene expression profiling in perilesional and contralateral areas after ischemia in rat brain. J. Cereb. Blood Flow Metab. 22 (2002) 153-160
30. Kitamura T., Sato N., Arai K., and Miyajima A. Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Cell 66 (1991) 1165-1174
31. Kovacs Z., Ikezaki K., Samoto K., Inamura T., and Fukui M. VEGF and flt. Expression time kinetics in rat brain infarct. Stroke 27 (1996) 1865-1872 discussion 1872-3
32. Li H., Kolluri S.K., Gu J., Dawson M.I., Cao X., Hobbs P.D., Lin B., Chen G., Lu J., Lin F., Xie Z., Fontana J.A., Reed J.C., and Zhang X. Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. Science 289 (2000) 1159-1164
33. Lu Y.M., Jia Z., Janus C., Henderson J.T., Gerlai R., Wojtowicz J.M., and Roder J.C. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP. J. Neurosci. 17 (1997) 5196-5205
34. Lu B., Rutledge B.J., Gu L., Fiorillo J., Lukacs N.W., Kunkel S.L., North R., Gerard C., and Rollins B.J. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J. Exp. Med. 187 (1998) 601-608
35. Lu X.C., Williams A.J., Yao C., Berti R., Hartings J.A., Whipple R., Vahey M.T., Polavarapu R.G., Woller K.L., Tortella F.C., and Dave J.R. Microarray analysis of acute and delayed gene expression profile in rats after focal ischemic brain injury and reperfusion. J. Neurosci. Res. 77 (2004) 843-857
36. Luo T., Xu Y., Hoffman T.L., Zhang T., Schilling T., and Sargent T.D. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Development 134 (2007) 1279-1289
37. Lutz P.L., and Nilsson G.E. Vertebrate brains at the pilot light. Respir. Physiol. Neurobiol. 141 (2004) 285-296
38. Martin R.L., Lloyd H.G., and Cowan A.I. The early events of oxygen and glucose deprivation: setting the scene for neuronal death?. Trends Neurosci. 17 (1994) 251-257
39. Matsuoka Y., Kitamura Y., Okazaki M., Sakata M., Tsukahara T., and Taniguchi T. Induction of heme oxygenase-1 and major histocompatibility complex antigens in transient forebrain ischemia. J. Cereb. Blood Flow Metab. 18 (1998) 824-832
40. Nilsson G.E., and Lutz P.L. Anoxia tolerant brains. J. Cereb. Blood Flow Metab. 24 (2004) 475-486
41. Raghavendra Rao V.L., Bowen K.K., Dhodda V.K., Song G., Franklin J.L., Gavva N.R., and Dempsey R.J. Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia. J. Neurochem. 83 (2002) 1072-1086
42. Raivich G., and Behrens A. Role of the AP-1 transcription factor c-Jun in developing, adult and injured brain. Prog. Neurobiol. 78 (2006) 347-363
43. Rickhag M., Wieloch T., Gido G., Elmer E., Krogh M., Murray J., Lohr S., Bitter H., Chin D.J., von Schack D., Shamloo M., and Nikolich K. Comprehensive regional and temporal gene expression profiling of the rat brain during the first 24 h after experimental stroke identifies dynamic ischemia-induced gene expression patterns, and reveals a biphasic activation of genes in surviving tissue. J. Neurochem. 96 (2006) 14-29
44. Ryter S.W., and Choi A.M. Heme oxygenase-1: redox regulation of a stress protein in lung and cell culture models. Antioxid. Redox Signal. 7 (2005) 80-91
45. Schmidt-Kastner R., Truettner J., Zhao W., Belayev L., Krieger C., Busto R., and Ginsberg M.D. Differential changes of bax, caspase-3 and p21 mRNA expression after transient focal brain ischemia in the rat. Brain Res. Mol. Brain Res. 79 (2000) 88-101
46. Schmidt-Kastner R., Zhang B., Belayev L., Khoutorova L., Amin R., Busto R., and Ginsberg M.D. DNA microarray analysis of cortical gene expression during early recirculation after focal brain ischemia in rat. Brain Res. Mol. Brain Res. 108 (2002) 81-93
47. Schmidt-Kastner R., Haberkamp M., Schmitz C., Hankeln T., and Burmester T. Neuroglobin mRNA expression after transient global brain ischemia and prolonged hypoxia in cell culture. Brain Res. 1103 (2006) 173-180
48. Sedlak T.W., and Snyder S.H. Bilirubin benefits: cellular protection by a biliverdin reductase antioxidant cycle. Pediatrics 113 (2004) 1776-1782
49. Sharp F.R., and Bernaudin M. HIF1 and oxygen sensing in the brain. Nat. Rev., Neurosci. 5 (2004) 437-448
50. Soehle M., Heimann A., and Kempski O. Postischemic application of lipid peroxidation inhibitor U-101033E reduces neuronal damage after global cerebral ischemia in rats. Stroke 29 (1998) 1240-1246 discussion 1246-7
51. Sonninen R., Virtanen T., Sivenius J., and Jolkkonen J. Gene expression profiling in the hippocampus of rats subjected to focal cerebral ischemia and enriched environment housing. Restor. Neurol. Neurosci. 24 (2006) 17-23
52. Soriano M.A., Tessier M., Certa U., and Gill R. Parallel gene expression monitoring using oligonucleotide probe arrays of multiple transcripts with an animal model of focal ischemia. J. Cereb. Blood Flow Metab. 20 (2000) 1045-1055
53. Sun Y., Jin K., Mao X.O., Zhu Y., and Greenberg D.A. Neuroglobin is up-regulated by and protects neurons from hypoxic-ischemic injury. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 15306-15311
54. Sun Y., Jin K., Peel A., Mao X.O., Xie L., and Greenberg D.A. Neuroglobin protects the brain from experimental stroke in vivo. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 3497-3500
55. Takebayashi K., Akazawa C., Nakanishi S., and Kageyama R. Structure and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-5. Identification of the neural precursor cell-specific promoter element. J. Biol. Chem. 270 (1995) 1342-1349
56. Tang Y., Lu A., Aronow B.J., Wagner K.R., and Sharp F.R. Genomic responses of the brain to ischemic stroke, intracerebral haemorrhage, kainate seizures, hypoglycemia, and hypoxia. Eur. J. Neurosci. 15 (2002) 1937-1952
57. Tureyen K., Brooks N., Bowen K., Svaren J., and Vemuganti R. Transcription factor early growth response-1 induction mediates inflammatory gene expression and brain damage following transient focal ischemia. J. Neurochem. 105 (2008) 1313-1324
58. Verzi M.P., Agarwal P., Brown C., McCulley D.J., Schwarz J.J., and Black B.L. The transcription factor MEF2C is required for craniofacial development. Dev. Cell 12 (2007) 645-652
59. Wang H., Zhan Y., Xu L., Feuerstein G.Z., and Wang X. Use of suppression subtractive hybridization for differential gene expression in stroke: discovery of CD44 gene expression and localization in permanent focal stroke in rats. Stroke 32 (2001) 1020-1027
60. Wu Z., Irizarry R.A., Gentleman R., Murillo F.M., and Spencer F. A model based background adjustment for oligonucleotide expression arrays. J. Am. Stat. Assoc. 99 (2004) 909-917
61. Yan S.F., Fujita T., Lu J., Okada K., Shan Zou Y., Mackman N., Pinsky D.J., and Stern D.M. Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress. Nat. Med. 6 (2000) 1355-1361
62. Yasukawa H., Yajima T., Duplain H., Iwatate M., Kido M., Hoshijima M., Weitzman M.D., Nakamura T., Woodard S., Xiong D., Yoshimura A., Chien K.R., and Knowlton K.U. The suppressor of cytokine signaling-1 (SOCS1) is a novel therapeutic target for enterovirus-induced cardiac injury. J. Clin. Invest. 111 (2003) 469-478
63. Yet S.F., McA'Nulty M.M., Folta S.C., Yen H.W., Yoshizumi M., Hsieh C.M., Layne M.D., Chin M.T., Wang H., Perrella M.A., Jain M.K., and Lee M.E. Human EZF, a Kruppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains. J. Biol. Chem. 273 (1998) 1026-1031
64. Yi J.H., Park S.W., Kapadia R., and Vemuganti R. Role of transcription factors in mediating post-ischemic cerebral inflammation and brain damage. Neurochem. Int. 50 (2007) 1014-1027