Changes in gene expression and assessment of DNA methylation in primary human hepatocytes and HepG2 cells exposed to the environmental contaminants-Hexabromocyclododecane and 17-β oestradiol

Toxicology

Volumn 256, Issue 3, 2009, Pages 143-151

  Aniagu, Stanley O ^a   Williams, Tim D ^a   Chipman, J Kevin ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

17 oestradiol; DNA methylation; Gene expression; Hepatocytes; Hexabromocyclododecane

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR ALPHA; HEXABROMOCYCLODODECANE; HISTONE H3; PROTEIN P16; THYROID HORMONE RECEPTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; CELL CYCLE REGULATION; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CARCINOMA; N CYM GENE; ONCOGENE C MYC; ONCOGENE H RAS; PRIORITY JOURNAL; PROMOTER REGION; RB1 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TBK1 GENE; UPREGULATION;

APOPTOSIS; CARCINOGENS, ENVIRONMENTAL; CELL CYCLE; CELL LINE, TUMOR; DNA; DNA METHYLATION; DNA PRIMERS; ESTRADIOL; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEPATOCYTES; HUMANS; HYDROCARBONS, BROMINATED; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION; RNA;

EID: 58349096469     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.10.017     Document Type: Article

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