Oestrogen receptor α is required for biochanin A-induced apolipoprotein A-1 mRNA expression in HepG2 cells

British Journal of Nutrition

Volumn 98, Issue 3, 2007, Pages 534-539

  Chan, Ming Yan ^a   Wai Man, Gho ^a   Chen, Zhen Yu ^a,b   Wang, Jun ^a   Leung, Lai K ^a,b  

^a Prince of Wales Hospital   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apolipoprotein A 1; Biochanin A; Liver cancer cells; Oestrogen receptors

Indexed keywords

APOLIPOPROTEIN A1; BIOCHANIN A; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME INHIBITOR; ESTROGEN RECEPTOR ALPHA; FIREFLY LUCIFERASE; FULVESTRANT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C;

ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; DNA FLANKING REGION; GENE AMPLIFICATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PLASMID; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

APOLIPOPROTEIN A-I; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; GENE EXPRESSION REGULATION; GENISTEIN; HUMANS; ISOFLAVONES; LUCIFERASES; PHYTOESTROGENS; PROMOTER REGIONS (GENETICS); PROTEIN KINASE INHIBITORS; RNA, MESSENGER; TRANSFECTION; TUMOR CELLS, CULTURED;

TRIFOLIUM PRATENSE;

EID: 34548042337     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114507750857     Document Type: Article

References (25)

1. Murray JL & Lopez AD (1996) The Global Burden of Disease: A Comprehensive Assessment of Global Mortality and Disability from Diseases, Injuries and Risk Factors in 1990 and Projected to 2020. Geneva: World Health Organization.
2. Adlercreutz H, Markkanen H & Watanabe S (1998) Plasma concentrations of phyto-oestrogens in Japanese men. Lancet 342, 1209-1210.
3. Scheiber MD, Liu JH, Subbiah MTR, Rebar RW & Setchell KDR (2001) Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women. Menopause 8, 384-392.
4. Fielding CJ & Fielding PE (1995) Molecular physiology of reverse cholesterol transport. J Lipid Res 36, 211-228.
5. Gustafsson JA (1999) Estrogen receptor β - a new dimension in estrogen mechanism of action. J Endocrinol 163, 379-383.
6. Shutt DA & Cox RI (1972) Steroid and phyto-estrogen binding to sheep uterine receptors in vitro. J Endocrinol 52, 291-310.
7. Kuiper GGJM, Lemmen JG, Carlsson B, Corton JC, Safe SH, van der Saag PT, van der Burg B & Gustafsson JA (1998) Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β. Endocrinology 139, 4252-4263.
8. Adlercreutz H (2003) Phytoestrogens and breast cancer. J Steroid Biochem Mol Biol 83, 113.
9. Jefferson WN, Padilla-Banks E, Clark G & Newbold RR (2002) Assessing estrogenic activity of phytochemicals using transcriptional activation and immature mouse uterotrophic responses. J Chromatogr B Analyt Technol. Biomed Life Sci 777, 179.
10. Javitt NB (1990) HepG2 cells as a resource for metabolic studies: lipoprotein, cholesterol and bile acids. FASEB J 4, 161-168.
11. Rash JM, Rothblat GH & Sparks CE (1981) Lipoprotein apolipoprotein synthesis by human hepatoma cells in culture. Biochim Biophys Acta 666, 294-298.
12. Zannis VI, Breslow JL, SanGiacomo TR, Aden DP & Knowles BB (1981) Characterization of the major apolipoproteins secreted by two human hepatoma cell lines. Biochemistry 20, 7089-7096.
13. Harnish DC, Evans MJ, Scicchitano MS, Bhat RA & Karathanasis SK (1998) Estrogen regulation of the apolipoprotein AI gene promoter through transcription cofactor sharing. J Biol Chem 273, 9270-9278.
14. Livak KJ & Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25, 402-408.
15. Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65, 55-63.
16. Lamon-Fava S & Micherone D (2004) Regulation of apoA-I gene expression mechanism of action of estrogen and genistein. J Lipid Res 45 106-112.
17. Beers A, Haas MJ, Wong NCW & Mooradian AD (2006) Inhibition of apolipoprotein AI gene expression by tumor necrosis factor α: Roles for MEK/ERK and JNK signaling. Biochemistry 45, 2408-2413.
18. Lamon-Fava S, Ordovas M & Schaefer EJ (1999) Estrogen increases apolipoprotein (apo) A-1 secretion in HepG2 cells by modulating transcription of the apoA-1 gene promoter. Arterioscler Thromb Vasc Biol 19, 2960-2965.
19. Lamon-Fava S (2000) Genistein activates apolipoprotein A-1 gene expression in the human hepatoma cell line HepG2. J Nutr 130 2489-2492.
20. Sastry KN, Seedorf U & Karthanasis SK (1988) Different cis-acting DNA elements control expression of the human apolipoprotein AI gene in different cell types. Mol Cell Biol 8, 605-614.
21. Harnish DC, Malik S, Kilbourne E, Costa R & Karathanasis SK (1996) Control of apolipoprotein A-I gene expression through synergistic interaction between hepatocyte nuclear factors 3 and 4. J Biol Chem 271, 13621-13628.
22. Harnish DC, Malik S & Karathanasis SK (1994) Activation of apolipoprotein A-I gene expression by the liver-enriched factor HNF-3. J Biol Chem 269, 28220-28226.
23. Kilbourne E, Widom R, Harnish DC, Malik S & Karathanasis SK (1995) Involvementof early growth response factor Egr1 in apolipoprotein AI gene transcription. J Biol Chem 270, 7004-7010.
24. Ivanov GS, Kater JM, Jha SH, Stutius EA, Sabharwal R, Tricarico MD, Ginsburg GS & Ozer JS (2003) Sp and GATA factors are critical for apolipoprotein AI downstream enhancer activity in huma HepG2 cells. Gene 323, 31-42.
25. Zhang X, Jiao JJ, Bhavnani BR & Tam SP (2001) Regulation of human apolipoprotein A-1 gene expression by equine estrogens. J Lipid Res 42, 1789-1800.