Mat1 inhibits peroxisome proliferator-activated receptor γ-mediated adipocyte differentiation

Molecular and Cellular Biology

Volumn 29, Issue 2, 2009, Pages 315-323

  Helenius, Katja ^a   Yang, Ying ^a   Alasaari, Jukka ^a   Mäkelä, Tomi P ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADIPONECTIN; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 7; CYCLIN H; CYCLINE; GENE PRODUCT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN MAT1; PROTEIN TAF10; TRANSCRIPTION FACTOR IIH; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; GENE; MAT1 GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION;

ADIPOCYTES; ADIPOGENESIS; ADIPOSE TISSUE, WHITE; AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; CELL DIVISION; CYCLIN-DEPENDENT KINASES; FIBROBLASTS; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PPAR GAMMA; SERINE; TRANSCRIPTION FACTOR TFIIH;

MAMMALIA;

EID: 58249112308     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00347-08     Document Type: Article

References (76)

1. Adamczewski, J. P., M. Rossignol, J. P. Tassan, E. A. Nigg, V. Moncollin, and J. M. Egly. 1996. MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH. EMBO J. 15:1877-1884.
2. Adams, M., M. J. Reginato, D. Shao, M. A. Lazar, and V. K. Chatterjee. 1997. Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J. Biol. Chem. 272:5128-5132.
3. Aguilar-Fuentes, J., V. Valadez-Graham, E. Reynaud, and M. Zurita. 2006. TFIIH trafficking and its nuclear assembly during early Drosophila embryo development. J. Cell Sci. 119:3866-3875.
4. Akoulitchev, S., T. P. Mäkelä, R. A. Weinberg, and D. Reinberg. 1995. Requirement for TFIIH kinase activity in transcription by RNA polymerase II. Nature 377:557-560.
5. Anton, M., and F. L. Graham. 1995. Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression. J. Virol. 69:4600-4606.
6. Araujo, S. J., F. Tirode, F. Coin, H. Pospiech, J. E. Syvaoja, M. Stucki, U. Hubscher, J. M. Egly, and R. D. Wood. 2000. Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK. Genes Dev. 14: 349-359.
7. Baross, A., Y. S. Butterfield, S. M. Coughlin, T. Zeng, M. Griffith, O. L. Griffith, A. S. Petrescu, D. E. Smailus, J. Khattra, H. L. McDonald, S. J. McKay, M. Moksa, R. A. Holt, and M. A. Marra. 2004. Systematic recovery and analysis of full-ORF human cDNA clones. Genome Res. 14:2083-2092.
8. Bartkova, J., M. Zemanova, and J. Bartek. 1996. Expression of CDK7/CAK in normal and tumor cells of diverse histogenesis, cell-cycle position and differentiation. Int. J. Cancer 66:732-737.
9. Bastien, J., S. Adam-Stitah, T. Riedl, J. M. Egly, P. Chambon, and C. Rochette-Egly. 2000. TFIIH interacts with the retinoic acid receptor gamma and phosphorylates its AF-1-activating domain through cdk7. J. Biol. Chem. 275:21896-21904.
10. Braissant, O., F. Foufelle, C. Scotto, M. Dauca, and W. Wahli. 1996. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137:354-366.
11. Brown, A. J., T. Jones, and J. Shuttleworth. 1994. Expression and activity of p40MO15, the catalytic subunit of cdk-activating kinase, during Xenopus oogenesis and embryogenesis. Mol. Biol. Cell 5:921-932.
12. Camp, H. S., and S. R. Tafuri. 1997. Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase. J. Biol. Chem. 272:10811-10816.
13. Cao, Z., R. M. Umek, and S. L. McKnight. 1991. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5:1538-1552.
14. Chawla, A., E. J. Schwarz, D. D. Dimaculangan, and M. A. Lazar. 1994. Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology 135:798-800.
15. Chen, D., T. Riedl, E. Washbrook, P. E. Pace, R. C. Coombes, J. M. Egly, and S. Ali. 2000. Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7. Mol. Cell 6:127-137.
16. Chen, J., S. Larochelle, X. Li, and B. Suter. 2003. Xpd/Ercc2 regulates CAK activity and mitotic progression. Nature 424:228-232.
17. Chen, Z., J. I. Torrens, A. Anand, B. M. Spiegelman, and J. M. Friedman. 2005. Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms. Cell Metab. 1:93-106.
18. Classon, M., B. K. Kennedy, R. Mulloy, and E. Harlow. 2000. Opposing roles of pRB and p107 in adipocyte differentiation. Proc. Natl. Acad. Sci. USA 97:10826-10831.
19. Cock, T. A., S. M. Houten, and J. Auwerx. 2004. Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm. EMBO Rep. 5:142-147.
20. Compe, E., P. Drane, C. Laurent, K. Diderich, C. Braun, J. H. Hoeijmakers, and J. M. Egly. 2005. Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations. Mol. Cell. Biol. 25:6065-6076.
21. Compe, E., M. Malerba, L. Soler, J. Marescaux, E. Borrelli, and J. M. Egly. 2007. Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH. Nat. Neurosci. 10:1414-1422.
22. Deato, M. D., and R. Tjian. 2007. Switching of the core transcription machinery during myogenesis. Genes Dev. 21:2137-2149.
23. Devault, A., A. M. Martinez, D. Fesquet, J. C. Labbe, N. Morin, J. P. Tassan, E. A. Nigg, J. C. Cavadore, and M. Doree. 1995. MAT1 ('menage a trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK. EMBO J. 14:5027-5036.
24. Fajas, L., R. L. Landsberg, Y. Huss-Garcia, C. Sardet, J. A. Lees, and J. Auwerx. 2002. E2Fs regulate adipocyte differentiation. Dev. Cell 3:39-49.
25. Falender, A. E., R. N. Freiman, K. G. Geles, K. C. Lo, K. Hwang, D. J. Lamb, P. L. Morris, R. Tjian, and J. S. Richards. 2005. Maintenance of spermatogenesis requires TAF4b, a gonad-specific subunit of TFIID. Genes Dev. 19:794-803.
26. Farmer, S. R. 2006. Transcriptional control of adipocyte formation. Cell Metab. 4:263-273.
27. Faye, G., M. Simon, J. G. Valay, D. Fesquet, and C. Facca. 1997. Rig2, a RING finger protein that interacts with the Kin28/Ccl1 CTD kinase in yeast. Mol. Gen. Genet. 255:460-466.
28. Feaver, W. J., J. Q. Svejstrup, N. L. Henry, and R. D. Kornberg. 1994. Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK. Cell 79:1103-1109.
29. Fisher, R. P., P. Jin, H. M. Chamberlin, and D. O. Morgan. 1995. Alternative mechanisms of CAK assembly require an assembly factor or an activating kinase. Cell 83:47-57.
30. Freiman, R. N., S. R. Albright, S. Zheng, W. C. Sha, R. E. Hammer, and R. Tjian. 2001. Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development. Science 293:2084-2087.
31. Ge, K., M. Guermah, C. X. Yuan, M. Ito, A. E. Wallberg, B. M. Spiegelman, and R. G. Roeder. 2002. Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis. Nature 417:563-567.
32. Gerhold, D. L., F. Liu, G. Jiang, Z. Li, J. Xu, M. Lu, J. R. Sachs, A. Bagchi, A. Fridman, D. J. Holder, T. W. Doebber, J. Berger, A. Elbrecht, D. E. Moller, and B. B. Zhang. 2002. Gene expression profile of adipocyte differentiation and its regulation by peroxisome proliferator-activated receptor-gamma agonists. Endocrinology 143:2106-2118.
33. Green, H., and O. Kehinde. 1975. An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell 5:19-27.
34. Green, H., and O. Kehinde. 1976. Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells. Cell 7:105-113.
35. Guo, X., and K. Liao. 2000. Analysis of gene expression profile during 3T3-L1 preadipocyte differentiation. Gene 251:45-53.
36. He, Q., H. Peng, S. J. Collins, T. J. Triche, and L. Wu. 2004. Retinoid-modulated MAT1 ubiquitinationand CAK activity. FASEB J. 18:1734-1736.
37. Holstege, F. C., E. G. Jennings, J. J. Wyrick, T. I. Lee, C. J. Hengartner, M. R. Green, T. R. Golub, E. S. Lander, and R. A. Young. 1998. Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95:717-728.
38. Hu, E., J. B. Kim, P. Sarraf, and B. M. Spiegelman. 1996. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPAR-gamma. Science 274:2100-2103.
39. Kanin, E. I., R. T. Kipp, C. Kung, M. Slattery, A. Viale, S. Hahn, K. M. Shokat, and A. Z. Ansari. 2007. Chemical inhibition of the TFIIH-associated kinase Cdk7/Kin28 does not impair global mRNA synthesis. Proc. Natl. Acad. Sci. USA 104:5812-5817.
40. Keriel, A., A. Stary, A. Sarasin, C. Rochette-Egly, and J. M. Egly. 2002. XPD mutations prevent TFIIH-dependent transactivation by nuclear receptors and phosphorylation of RARalpha. Cell 109:125-135.
41. Kim, J. M., J. T. McGaughy, R. K. Bogle, and S. E. Ravnik. 2001. Meiotic expression of the cyclin H/Cdk7 complex in male germ cells of the mouse. Biol. Reprod. 64:1400-1408.
42. Klefstrom, J., E. Arighi, T. Littlewood, M. Jaattela, E. Saksela, G. I. Evan, and K. Alitalo. 1997. Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-kappaB activation. EMBO J. 16:7382-7392.
43. Komarnitsky, P., E. J. Cho, and S. Buratowski. 2000. Different phosphory-lated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev. 14:2452-2460.
44. Korsisaari, N., D. J. Rossi, A. Paetau, P. Charnay, M. Henkemeyer, and T. P. Makela. 2002. Conditional ablation of the Mat1 subunit of TFIIH in Schwann cells provides evidence that Mat1 is not required for general transcription. J. Cell Sci. 115:4275-4284.
45. Larochelle, S., K. Merrick, M. Terret, L. Wohbold, N. M. Barboza, C. Zhang, K. M. Shokat, P. V. Jallepalli, and R. P. Fisher. 2007. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Mol. Cell 25:839-850.
46. Larochelle, S., J. Pandur, R. P. Fisher, H. K. Salz, and B. Suter. 1998. Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity. Genes Dev. 12:370-381.
47. Leclerc, V., S. Raisin, and P. Leopold. 2000. Dominant-negative mutants reveal a role for the Cdk7 kinase at the mid-blastula transition in Drosophila embryos. EMBO J. 19:1567-1575.
48. Lee, K. M., I. Miklos, H. Du, S. Watt, Z. Szilagyi, J. E. Saiz, R. Madabhushi, C. J. Penkett, M. Sipiczki, J. Bahler, and R. P. Fisher. 2005. Impairment of the TFIIH-associated CDK-activating kinase selectively affects cell cycle-regulated gene expression in fission yeast. Mol. Biol. Cell 16:2734-2745.
49. Lehmann, J. M., L. B. Moore, T. A. Smith-Oliver, W. O. Wilkison, T. M. Willson, and S. A. Kliewer. 1995. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J. Biol. Chem. 270:12953-12956.
50. Mäkelä, T. P., J. D. Parvin, J. Kim, L. J. Huber, P. A. Sharp, and R. A. Weinberg. 1995. A kinase-deficient transcription factor IIH is functional in basal and activated transcription. Proc. Natl. Acad. Sci. USA 92:5174-5178.
51. Mäkelä, T. P., J.-P. Tassan, E. A. Nigg, S. Frutiger, G. J. Hughes, and R. A. Weinberg. 1994. A cyclin associating with the CDK-activating kinase MO15. Nature 371:254-257.
52. II30) is necessary for TFIID stability and early embryogenesis in mice. Mol. Cell. Biol. 23:4307-4318.
53. Mu, D., D. S. Hsu, and A. Sancar. 1996. Reaction mechanism of human DNA repair excision nuclease. J. Biol. Chem. 271:8285-8294.
54. Phatnani, H. P., and A. L. Greenleaf. 2006. Phosphorylation and functions of the RNA polymerase II CTD. Genes Dev. 20:2922-2936.
55. Prusty, D., B. H. Park, K. E. Davis, and S. R. Farmer. 2002. Activation of MEK/ERK signaling promotes adipogenesis by enhancing peroxisome pro-liferator-activated receptor gamma (PPARgamma) and C/EBPalpha gene expression during the differentiation of 3T3-L1 preadipocytes. J. Biol. Chem. 277:46226-46232.
56. Puigserver, P., G. Adelmant, Z. Wu, M. Fan, J. Xu, B. O'Malley, and B. M. Spiegelman. 1999. Activation of PPARgamma coactivator-1 through transcription factor docking. Science 286:1368-1371.
57. Rangwala, S. M., B. Rhoades, J. S. Shapiro, A. S. Rich, J. K. Kim, G. I. Shulman, K. H. Kaestner, and M. A. Lazar. 2003. Genetic modulation of PPARgamma phosphorylation regulates insulin sensitivity. Dev. Cell 5: 657-663.
58. Reginato, M. J., S. L. Krakow, S. T. Bailey, and M. A. Lazar. 1998. Prostaglandins promote and block adipogenesis through opposing effects on peroxisome proliferator-activated receptor gamma. J. Biol. Chem. 273:1855-1858.
59. Rochette-Egly, C., S. Adam, M. Rossignol, J. M. Egly, and P. Chambon. 1997. Stimulation of RAR alpha activation function AF-1 through binding to the general transcription factor TFIIH and phosphorylation by CDK7. Cell 90:97-107.
60. Rosales, J., B. Han, and K. Y. Lee. 2003. Cdk7 functions as a cdk5 activating kinase in brain. Cell. Physiol. Biochem. 13:285-296.
61. Rosen, E. D., C. H. Hsu, X. Wang, S. Sakai, M. W. Freeman, F. J. Gonzalez, and B. M. Spiegelman. 2002. C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes Dev. 16:22-26.
62. Rosen, E. D., P. Sarraf, A. E. Troy, G. Bradwin, K. Moore, D. S. Milstone, B. M. Spiegelman, and R. M. Mortensen. 1999. PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro. Mol. Cell 4:611-617.
63. Rossi, D. J., A. Londesborough, N. Korsisaari, A. Pihlak, E. Lehtonen, M. Henkemeyer, and T. P. Makela. 2001. Inabilityto enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1. EMBO J. 20:2844-2856.
64. Roy, R., J. P. Adamczewski, T. Seroz, W. Vermeulen, J. P. Tassan, L. Schaef-fer, E. A. Nigg, J. H. Hoeijmakers, and J. M. Egly. 1994. The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor. Cell 79:1093-1101.
65. Sano, M., Y. Izumi, K. Helenius, M. Asakura, D. J. Rossi, M. Xie, G. Taffet, L. Hu, R. G. Pautler, C. R. Wilson, S. Boudina, E. D. Abel, H. Taegtmeyer, F. Scaglia, B. H. Graham, A. Kralli, N. Shimizu, H. Tanaka, T. P. Makela, and M. D. Schneider. 2007. Menage-a-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1. Cell Metab. 5:129-142.
66. Serizawa, H., T. P. Makela, J. W. Conaway, R. C. Conaway, R. A. Weinberg, and R. A. Young. 1995. Association of Cdk-activating kinase subunits with transcription factor TFIIH. Nature 374:280-282.
67. Shao, D., S. M. Rangwala, S. T. Bailey, S. L. Krakow, M. J. Reginato, and M. A. Lazar. 1998. Interdomain communication regulating ligand binding by PPAR-gamma. Nature 396:377-380.
68. Sung, P., S. N. Guzder, L. Prakash, and S. Prakash. 1996. Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair. J. Biol. Chem. 271:10821-10826.
69. Tassan, J. P., M. Jaquenoud, A. M. Fry, S. Frutiger, G. J. Hughes, and E. A. Nigg. 1995. In vitro assembly of a functional human CDK7-cyclin H complex requires MAT1, a novel 36 kDa RING finger protein. EMBO J. 14:5608-5617.
70. Tassan, J. P., S. J. Schultz, J. Bartek, and E. A. Nigg. 1994. Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase). J. Cell Biol. 127:467-478.
71. Tong, Q., G. Dalgin, H. Xu, C. N. Ting, J. M. Leiden, and G. S. Hotamisligil. 2000. Function of GATA transcription factors in preadipocyte-adipocyte transition. Science 290:134-138.
72. Tontonoz, P., E. Hu, and B. M. Spiegelman. 1994. Stimulation of adipogen-esis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell 79:1147-1156.
73. Valay, J. G., M. F. Dubois, O. Bensaude, and G. Faye. 1996. Ccl1, a cyclin associated with protein kinase Kin28, controls the phosphorylation of RNA polymerase II largest subunit and mRNA transcription. C. R. Acad. Sci. III 319:183-189.
74. Valay, J. G., M. Simon, M. F. Dubois, O. Bensaude, C. Facca, and G. Faye. 1995. The KIN28 gene is required both for RNA polymerase II mediated transcription and phosphorylation of the Rpb1p CTD. J. Mol. Biol. 249:535-544.
75. Wallenfang, M. R., and G. Seydoux. 2002. cdk-7 is required for mRNA transcription and cell cycle progression in Caenorhabditis elegans embryos. Proc. Natl. Acad. Sci. USA 99:5527-5532.
76. Yeh, W. C., Z. Cao, M. Classon, and S. L. McKnight. 1995. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev. 9:168-181.