Matrix-free high-resolution imaging mass spectrometry with high-energy ion projectiles

Journal of Mass Spectrometry

Volumn 44, Issue 1, 2009, Pages 128-136

  Nakata, Yoshihiko ^a   Honda, Yoshiro ^a   Ninomiya, Satoshi ^a   Seki, Toshio ^a,b   Aokic, Takaaki ^a,b   Matsuo, Jiro ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Biomolecule; Electronic sputtering; MeV ion beam; Molecular imaging; SIMS

Indexed keywords

AMINES; BIOMOLECULES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION BEAM LITHOGRAPHY; ION BEAMS; ION SOURCES; MASS SPECTROMETERS; MASS SPECTROMETRY; SECONDARY EMISSION; SECONDARY ION MASS SPECTROMETRY; SIZE DISTRIBUTION; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; THICKNESS MEASUREMENT;

BIOLOGICAL TISSUES; CURRENT TECHNIQUES; ELECTRONIC EXCITATIONS; ELECTRONIC SPUTTERING; ENERGY IONS; HIGH ENERGIES; HIGH RESOLUTIONS; IMAGING MASS SPECTROMETRIES; ION IMAGES; KEV IONS; LATERAL RESOLUTIONS; MEV ION BEAM; MICROPATTERNED; MOLECULAR IMAGING; MOLECULAR ION YIELDS; MOLECULAR SPECIES; NEW SYSTEMS; POWERFUL TOOLS; SECONDARY IONS; SIMS; SPATIAL DISTRIBUTION OF; SURFACE REGIONS;

IONS;

ANALYTIC METHOD; ARTICLE; ENERGY; MASS; MASS SPECTROMETRY; PEPTIDE ANALYSIS; PRIORITY JOURNAL; SURFACE PROPERTY;

DIAGNOSTIC IMAGING; IMAGE PROCESSING, COMPUTER-ASSISTED; IONS; MASS SPECTROMETRY; MOLECULAR WEIGHT; PEPTIDES; SENSITIVITY AND SPECIFICITY;

EID: 58249107993     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1482     Document Type: Article

References (35)

1. D. G. Castner, B.D. Ratner. Biomedical surface science: foundations to frontiers. Surface Science 2002, 500, 28.
2. P. Chaurand, S. A. Schwartz, R. M. Caprioli. Profiling and imaging proteins in tissue sections by MS. Analytical Chemistry 2004, 76, 87A.
3. S. Khatib-Shahidi, M. Andersson, J. L. Herman, T. A. Gillespie, R. M. Caprioli . Direct molecular analysis of whole-body animal tissue sections by imaging MALDI mass spectrometry. Analytical Chemistry 2006, 78, 6448.
4. P. Chaurand, R. M. Caprioli. Direct profiling and imaging of peptides and proteins from mammalian cells and tissue sections by mass spectrometry. Electrophoresis 2002, 23, 3125.
5. M. Stoeckli, D. Staab, M. Staufenbiel, K. H. Wiederhold, L. Signor. Molecular imaging of amyloid β peptides in mouse brain sections using mass spectrometry. Analytical Biochemistry 2002 311,, 33.
6. S. G. Ostrowski, C. T. Van Bell, N. Winograd, A. G. Ewing. Mass spectrometric imaging of highly curved membranes during tetrahymena mating. Science 2004, 305, 71.
7. J. L. Guerquin-Kern, T. D. Wu, C. Quintana, A. Croisy. Progress in analytical imaging of the cell by dynamic secondary ion mass spectrometry (SIMS microscopy). Biochimica et Biophysica Acta 2005, 1724, 228.
8. M. L. Kraft, P. K. Weber, M. L. Long, I. D. Hutcheon, S. G. Boxer. Phase separation of lipid membranes analyzed with high-resolution secondary ion mass spectrometry. Science 2006, 313, 1948.
9. 15N-labeled phenylalanine in human glioblastoma cells: relevance of subcellular scale observations to BPA-mediated boron neutron capture therapy of cancer. International Journal of Mass Spectrometry 2007 260,, 90.
10. + polyatomic primary ion beam for analysis of organic thin films by secondary ionmass spectrometry. Rapid Communications in Mass Spectrometry 1998, 12, 1303.
11. N. Winograd. The magic of cluster SIMS. Analytical Chemistry 2005, 77, 142A.
12. K. J. Wu, R. W. Odom. Matrix-enhanced secondary ion mass spectrometry: a method for molecular analysis of solid surfaces. Analytical Chemistry 1996, 68, 873.
13. L.A. McDonnell, S. R. Piersma, A. F. M. Altelaar, T. H. Mize, S. L. Luxembourg, P. D. E. M. Verhaert, J. van Minnen, R. M. A. Heeren. Subcellular imaging mass spectrometry of brain tissue. Journal of Mass Spectrometry 2005, 40, 160.
14. A. Delcorte, P. Bertrand. Interest of silver and gold metallization for molecular SIMS and SIMS imaging. Applied Surface Science 2004, 231, 250.
15. R. M. A. Heeren, L. A. McDonell, E. Amstalden, S. L. Luxembourg, A. F. M. Altelaar, S. R. Piersma. Why don't biologists use SIMS? A critical evaluation of imaging MS. Applied Surface Science 2006, 252, 6827.
16. A. Delcorte. Matrix-enhanced secondary ion mass spectrometry: the alchemist's solution? Applied Surface Science 2006, 252, 6582.
17. D. F. Torgerson, R. P. Skowronski, R. D. Macfarlane. New approach to the mass spectroscopy of non-volatile compounds. Biochemical and Biophysical Research Communications 1974, 60, 616.
18. B. U. R. Sundqvist, P. Roepstorff, J. Fohlman, A. Hedin, P. Håkansson, I. Kamensky, M. Lindberg, M. Salehpour, G. Säwe. Molecular weight determinations of proteins by californium plasma desorption mass spectrometry. Science 1984, 226, 696.
19. 252Cf-plasma desorption mass spectrometry I - a historical perspective. Biological Mass Spectrometry 1993, 22, 677.
20. R. D. Macfarlane. Mass spectrometry of biomolecules: from PDMS to MALDI. Brazilian Journal of Physics 1999, 29, 415.
21. S. Tanaka, T. Akaike, J. Fang, T. Beppu, M. Ogawa, F. Tamura, Y. Miyamoto, H. Maeda. Antiapoptotic effect of haem oxygenase-I induced by nitric oxide in experimental solid tumour. British Journal of Cancer 2003, 88, 902.
22. G. Säve, P. Håkansson, B. U. R. Sundqvist, E. Söderström, S. E. Lindquist, J. Berg. Desorption of secondary ions from Langmuir-Blodgett films following bombardment with fast heavy ions. International Journal of Mass Spectrometry and Ion Processes 1987, 78, 259.
23. G. Säve, P. Håkansson, B. U. R. Sundqvist, U. Jönsson. Sample film-thickness influence on fast heavy-ion induced desorption yields of biomolecular ions. Nuclear Instruments and Methods in Physical Research 1987, B26, 571.
24. J. F. Ziegler, J. P. Biersack, U. Littmark. The Stopping and Range of Ions in Solids. Pergamon Press: New York, 1985.
25. R.E. Johnson, B. U. R. Sundqvist. Electronic sputtering: from atomic physics to continuum mechanics. Physics Today 1992, 45, 28.
26. A. Hedin, P. Häkansson, M. Salehpour, B. U. R. Sundqvist. Fast-ion-induced erosion of leucine as a function of the electronic stopping power. Physical Review 1987, B35, 7377.
27. Y. Nakata, S. Ninomiya, J. Matsuo. Secondary ion emission from bio-molecular thin films under ion bombardment. Nuclear Instruments and Methods in Physical Research 2007, B256, 489.
28. + desorbed from LiF. Physical Review Letters 2000, 84, 5904.
29. 60 primary ion beam system for time of flight secondary ion mass spectrometry: its development and secondary ion yield characteristics. Analytical Chemistry 2003, 75, 1754.
30. D. Touboul, F. Kollmer, E. Niehuis, A. Brunelle, O. Laprevote. Improvement of biological time-of-flight-secondary ion mass spectrometry imaging with a bismuth cluster ion source. Journal of the American Society for Mass Spectrometry 2005, 16, 1608.
31. +, primary ions. International Journal of Mass Spectrometry 2007, 260, 146.
32. T. Kamiya, T. Suda, R. Tanaka. High energy single ion hit system combined with heavy ion microbeam apparatus. Nuclear Instruments and Methods in Physical Research 1996, B118, 423.
33. G. Dollinger, V. Hable, A. Hauptner, R. Krücken, P. Reichart, A. A. Friedl, G. Drexler, T. Cremer, S. Dietzel. Microirradiation of cells with energetic heavy ions. Nuclear Instruments and Methods in Physical Research 2005, B231, 195.
34. K. Ishii, A. Sugimoto, A. Tanaka, T. Satoh, S. Matsuyama, H. Yamazaki, C. Akama, T. Amartivan, H. Endoh, Y. Oishi, H. Yuki, S. Sugihara, M. Satoh, T. Kamiya, T. Sakai, K. Arakawa, M. Saidoh, S. Oikawa. Elemental analysis of cellular samples by in-air micro-PIXE. Nuclear Instruments and Methods in Physical Research 2001, B181, 448.
35. P. Håkansson. Desorption experiments on organic insulators with high energy particle beams. Mat. Fys. Medd 1993, 43, 593.