Insulin and epidermal growth factor suppress basal glucose-6-phosphatase catalytic subunit gene transcription through overlapping but distinct mechanisms

Biochemical Journal

Volumn 417, Issue 2, 2009, Pages 611-620

  Onuma, Hiroshi ^a   Oeser, James K ^a   Nelson, Bryce A ^a   Wang, Yingda ^a   Flemming, Brian P ^a   Scheving, Lawrence A ^a   Russell, William E ^a   O'Brien, Richard M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Epidermal growth factor (EGF); FOXO1; Glucocorticoid; Glucose 6 phosphatase; Insulin; Transcription

Indexed keywords

CATALYTIC SUBUNITS; EPIDERMAL GROWTH FACTOR (EGF); EPIDERMAL GROWTH FACTORS; FOXO1; FUSION GENES; GENE TRANSCRIPTIONS; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOSE 6 PHOSPHATES; GLUCOSE-6-PHOSPHATASE; HEPATOCYTE; HEPATOCYTES; HEPATOMA CELLS; HEPG2 CELLS; IN-VIVO; SELECTIVE MUTATION;

BINDING ENERGY; BINDING SITES; BIOACTIVITY; GLUCOSE; INSULIN; PEPTIDES;

TRANSCRIPTION;

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUCOCORTICOID RECEPTOR; GLUCOSE 6 PHOSPHATASE; HEPATOCYTE NUCLEAR FACTOR 3BETA; INSULIN; TRANSCRIPTION FACTOR FKHR; FOXA1 PROTEIN, HUMAN; FOXA2 PROTEIN, HUMAN; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL CULTURE; CELL ISOLATION; CELL STRAIN HEPG2; CONTROLLED STUDY; ENZYME ACTIVE SITE; GENE EXPRESSION; GENE FUSION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; RAT; TRANSCRIPTION REGULATION; ANIMAL; BIOCATALYSIS; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; LIVER; MALE; METABOLISM; MUTATION; PROMOTER REGION;

ANIMALS; BINDING SITES; BIOCATALYSIS; CELLS, CULTURED; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE-6-PHOSPHATASE; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 3-ALPHA; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HUMANS; INSULIN; LIVER; MALE; MICE; MUTATION; PROMOTER REGIONS, GENETIC; PROTEIN SUBUNITS; RATS; TRANSCRIPTION, GENETIC;

EID: 58249092342     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20080999     Document Type: Article

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