메뉴 건너뛰기




Volumn 6, Issue SUPPL. 1, 2008, Pages 86-93

Pathogenesis and management of osteoporosis in thalassemia

Author keywords

Bisphosphonates; Osteoporosis; Pathogenesis; Thalassemia; Therapy

Indexed keywords

ALENDRONIC ACID; BISPHOSPHONIC ACID DERIVATIVE; CALCITONIN; CALCIUM; CHORIONIC GONADOTROPIN; CLODRONIC ACID; COLECALCIFEROL; DEFEROXAMINE; ESTROGEN; HEMOGLOBIN; HYDROXYUREA; IRON CHELATING AGENT; PAMIDRONIC ACID; PLACEBO; SOMATOMEDIN; VITAMIN D; ZOLEDRONIC ACID;

EID: 58149490842     PISSN: 15654753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (38)

References (92)
  • 2
    • 0024191728 scopus 로고
    • Incidence and treatment of fractures in thalassemia
    • Michelson J, Cohen A. Incidence and treatment of fractures in thalassemia. J Orthop Trauma 1988;2:29-32
    • (1988) J Orthop Trauma , vol.2 , pp. 29-32
    • Michelson, J.1    Cohen, A.2
  • 3
    • 0025095185 scopus 로고
    • Musculoskeletal problems in hemoglobinopathy
    • Johanson NA. Musculoskeletal problems in hemoglobinopathy. Orthop Clin North Am 1990;21:191-198
    • (1990) Orthop Clin North Am , vol.21 , pp. 191-198
    • Johanson, N.A.1
  • 4
    • 0026634840 scopus 로고
    • Bone density, mineral content, and cortical index in patients with thalassemia major and the correlation to their bone fractures, blood transfusions, and treatment with desferrioxamine
    • Orvieto R, Leichter I, Rachmilewitz EA, Margulies JY. Bone density, mineral content, and cortical index in patients with thalassemia major and the correlation to their bone fractures, blood transfusions, and treatment with desferrioxamine. Calcif Tissue Int 1992;50:397-399
    • (1992) Calcif Tissue Int , vol.50 , pp. 397-399
    • Orvieto, R.1    Leichter, I.2    Rachmilewitz, E.A.3    Margulies, J.Y.4
  • 6
    • 0031851068 scopus 로고    scopus 로고
    • The morbidity of bone disease in thalassemia
    • Vichinsky EP. The morbidity of bone disease in thalassemia. Ann NY Acad Sci 1998;850:344-348
    • (1998) Ann NY Acad Sci , vol.850 , pp. 344-348
    • Vichinsky, E.P.1
  • 10
    • 5644257032 scopus 로고    scopus 로고
    • New insights into the pathophysiology and management of osteoporosis in patients with beta thalassaemia
    • Voskaridou E, Terpos E. New insights into the pathophysiology and management of osteoporosis in patients with beta thalassaemia. Br J Haematol 2004;127:127-139
    • (2004) Br J Haematol , vol.127 , pp. 127-139
    • Voskaridou, E.1    Terpos, E.2
  • 11
    • 0030848911 scopus 로고    scopus 로고
    • Incidence of endocrine complications and clinical disease severity related to genotype analysis and iron overload in patients with beta-thalassaemia
    • Jensen CE, Tuck SM, Old J, Morris RW, Yardumian A, De Sanctis V, Hoffbrand AV, Wonke B. Incidence of endocrine complications and clinical disease severity related to genotype analysis and iron overload in patients with beta-thalassaemia. Eur J Haematol 1997;59:76-81
    • (1997) Eur J Haematol , vol.59 , pp. 76-81
    • Jensen, C.E.1    Tuck, S.M.2    Old, J.3    Morris, R.W.4    Yardumian, A.5    De Sanctis, V.6    Hoffbrand, A.V.7    Wonke, B.8
  • 14
    • 0023986884 scopus 로고
    • High-dose desferrioxamine as a cause of growth failure in thalassemic patients
    • letter
    • Piga A, Luzzatto L, Capalbo P, Gambotto S, Tricta F, Gabutti V. High-dose desferrioxamine as a cause of growth failure in thalassemic patients. Eur J Haematol 1988;40:380-381 (letter)
    • (1988) Eur J Haematol , vol.40 , pp. 380-381
    • Piga, A.1    Luzzatto, L.2    Capalbo, P.3    Gambotto, S.4    Tricta, F.5    Gabutti, V.6
  • 16
    • 0029013459 scopus 로고
    • Short stature in homozygous beta-thalassaemia is due to disproportionate truncal shortening
    • Rodda CP, Reid ED, Johnson S, Doery J, Matthews R, Bowden DK. Short stature in homozygous beta-thalassaemia is due to disproportionate truncal shortening. Clin Endocrinol 1995;42:587-592
    • (1995) Clin Endocrinol , vol.42 , pp. 587-592
    • Rodda, C.P.1    Reid, E.D.2    Johnson, S.3    Doery, J.4    Matthews, R.5    Bowden, D.K.6
  • 18
    • 0033536288 scopus 로고    scopus 로고
    • The beta-thalassemias
    • Olivieri NF. The beta-thalassemias. N Engl J Med 1999;341:99-109
    • (1999) N Engl J Med , vol.341 , pp. 99-109
    • Olivieri, N.F.1
  • 19
  • 20
    • 0034883410 scopus 로고    scopus 로고
    • Effects of hormonal replacement therapy on bone metabolism in young adults with beta-thalassemia major
    • Lasco A, Morabito N, Gaudio A, Buemi M, Wasniewska M & Frisina N. Effects of hormonal replacement therapy on bone metabolism in young adults with beta-thalassemia major. Osteoporos Int 2001;12:570-575
    • (2001) Osteoporos Int , vol.12 , pp. 570-575
    • Lasco, A.1    Morabito, N.2    Gaudio, A.3    Buemi, M.4    Wasniewska, M.5    Frisina, N.6
  • 29
    • 84995839573 scopus 로고
    • Hereditary 1 alpha, 25-dihydroxyvitamin D-resistant rickets resulting from a mutation in the vitamin D receptor deoxyribonucleic acid-binding domain
    • Malloy PJ, Weisman Y, Feldman D. Hereditary 1 alpha, 25-dihydroxyvitamin D-resistant rickets resulting from a mutation in the vitamin D receptor deoxyribonucleic acid-binding domain. J Clin Endocrinol Metab 1994;78:313-316
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 313-316
    • Malloy, P.J.1    Weisman, Y.2    Feldman, D.3
  • 31
    • 0030448391 scopus 로고    scopus 로고
    • Are vitamin D receptor polymorphisms associated with bone mineral density? A meta-analysis
    • Cooper GS, Umbach DM. Are vitamin D receptor polymorphisms associated with bone mineral density? A meta-analysis. J Bone Miner Res 1996;11:1841-1849
    • (1996) J Bone Miner Res , vol.11 , pp. 1841-1849
    • Cooper, G.S.1    Umbach, D.M.2
  • 32
    • 0030999773 scopus 로고    scopus 로고
    • A sequence variation: 713-8delC in the transforming growth factor-beta 1 gene has higher prevalence in osteoporotic women than in normal women and is associated with very low bone mass in osteoporotic women and increased bone turnover in both osteoporotic and normal women
    • Langdahl BL, Knudsen JY, Jensen HK, Gregersen N, Eriksen EF. A sequence variation: 713-8delC in the transforming growth factor-beta 1 gene has higher prevalence in osteoporotic women than in normal women and is associated with very low bone mass in osteoporotic women and increased bone turnover in both osteoporotic and normal women. Bone 1997;20:289-294
    • (1997) Bone , vol.20 , pp. 289-294
    • Langdahl, B.L.1    Knudsen, J.Y.2    Jensen, H.K.3    Gregersen, N.4    Eriksen, E.F.5
  • 36
    • 0343766475 scopus 로고    scopus 로고
    • Nonassociation of estrogen receptor genotypes with bone mineral density and estrogen responsiveness to hormone replacement therapy in Korean postmenopausal women
    • Han KO, Moon IG, Kang YS, Chung HY, Min HK, Han IK. Nonassociation of estrogen receptor genotypes with bone mineral density and estrogen responsiveness to hormone replacement therapy in Korean postmenopausal women. J Clin Endocrinol Metab 1997;82:991-995
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 991-995
    • Han, K.O.1    Moon, I.G.2    Kang, Y.S.3    Chung, H.Y.4    Min, H.K.5    Han, I.K.6
  • 37
    • 0028943887 scopus 로고
    • The contribution of hypogonadism to the development of osteoporosis in thalassaemia major: New therapeutic approaches
    • Anapliotou ML, Kastanias IT, Psara P, Evangelou EA, Liparaki M, Dimitriou P. The contribution of hypogonadism to the development of osteoporosis in thalassaemia major: new therapeutic approaches. Clin Endocrinol 1995;42:279-287
    • (1995) Clin Endocrinol , vol.42 , pp. 279-287
    • Anapliotou, M.L.1    Kastanias, I.T.2    Psara, P.3    Evangelou, E.A.4    Liparaki, M.5    Dimitriou, P.6
  • 39
    • 0034773091 scopus 로고    scopus 로고
    • Clinical management of beta-thalassemia major
    • Wonke B. Clinical management of beta-thalassemia major. Semin Hematol 2001;38:350-359
    • (2001) Semin Hematol , vol.38 , pp. 350-359
    • Wonke, B.1
  • 43
    • 0036938971 scopus 로고    scopus 로고
    • Patterns of bone diseases in transfusion-dependent homozygous thalassaemia major: Predominance of osteoporosis and desferrioxamine-induced bone dysplasia
    • Chan YL, Pang LM, Chik KW, Cheng JC, Li CK. Patterns of bone diseases in transfusion-dependent homozygous thalassaemia major: predominance of osteoporosis and desferrioxamine-induced bone dysplasia. Pediatr Radiol 2002;32:492-497
    • (2002) Pediatr Radiol , vol.32 , pp. 492-497
    • Chan, Y.L.1    Pang, L.M.2    Chik, K.W.3    Cheng, J.C.4    Li, C.K.5
  • 45
    • 0037335049 scopus 로고    scopus 로고
    • Bone mineral density, biochemical and hormonal profiles in suboptimatly treated children and adolescents with beta-thalassaemia disease
    • Mahachoklertwattana P, Chuansumrit A, Sirisriro R, Choubtum L, Sriphrapradang A, Rajatanavin R. Bone mineral density, biochemical and hormonal profiles in suboptimatly treated children and adolescents with beta-thalassaemia disease. Clin Endocrinol 2003;58:273-279
    • (2003) Clin Endocrinol , vol.58 , pp. 273-279
    • Mahachoklertwattana, P.1    Chuansumrit, A.2    Sirisriro, R.3    Choubtum, L.4    Sriphrapradang, A.5    Rajatanavin, R.6
  • 46
    • 0028306362 scopus 로고
    • Assessment of fracture risks and its application to screening for post-menopausal osteoporosis. Report of a WHO Study Group
    • World Health Organization
    • World Health Organization. Assessment of fracture risks and its application to screening for post-menopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Ser 1994;843:1-129
    • (1994) World Health Organ Tech Rep Ser , vol.843 , pp. 1-129
  • 47
    • 0032945401 scopus 로고    scopus 로고
    • Importance of preclinical studies in the development of drugs for treatment of osteoporosis: A review related to the 1998 WHO guidelines
    • Bonjour JP, Ammann P, Rizzoli R. Importance of preclinical studies in the development of drugs for treatment of osteoporosis: a review related to the 1998 WHO guidelines. Osteoporos Int 1999;9:379-393
    • (1999) Osteoporos Int , vol.9 , pp. 379-393
    • Bonjour, J.P.1    Ammann, P.2    Rizzoli, R.3
  • 48
    • 0033926167 scopus 로고    scopus 로고
    • Interpretation of bone mineral density measurement and its change
    • Nguyen TV, Pocock N, Eisman JA. Interpretation of bone mineral density measurement and its change. J Clin Densitom 2000;3:107-119
    • (2000) J Clin Densitom , vol.3 , pp. 107-119
    • Nguyen, T.V.1    Pocock, N.2    Eisman, J.A.3
  • 49
    • 0036402485 scopus 로고    scopus 로고
    • What are the criteria by which a densitometric diagnosis of osteoporosis can be made in males and non-Caucasians?
    • Binkley NC, Schmeer P, Wasnich RD, Lenchik L. What are the criteria by which a densitometric diagnosis of osteoporosis can be made in males and non-Caucasians? J Clin Densitom 2002;5:19-27
    • (2002) J Clin Densitom , vol.5 , pp. 19-27
    • Binkley, N.C.1    Schmeer, P.2    Wasnich, R.D.3    Lenchik, L.4
  • 50
    • 0034047564 scopus 로고    scopus 로고
    • Iron deposition in the anterior pituitary in homozygous beta-thalassemia: MRI evaluation and correlation with gonadal function
    • Berkovitch M, Bistritzer T, Milone SD, Perlman K, Kucharczyk W, Olivieri NF. Iron deposition in the anterior pituitary in homozygous beta-thalassemia: MRI evaluation and correlation with gonadal function. J Pediatr Endocrinol Metab 2000;13:179-184
    • (2000) J Pediatr Endocrinol Metab , vol.13 , pp. 179-184
    • Berkovitch, M.1    Bistritzer, T.2    Milone, S.D.3    Perlman, K.4    Kucharczyk, W.5    Olivieri, N.F.6
  • 51
    • 0031955217 scopus 로고    scopus 로고
    • Riggs BL, Khosla S, Melton LJ 3rd. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res 1998;13:763-773
    • Riggs BL, Khosla S, Melton LJ 3rd. A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men. J Bone Miner Res 1998;13:763-773
  • 52
    • 0033690895 scopus 로고    scopus 로고
    • The mechanisms of estrogen regulation of bone resorption
    • Riggs BL. The mechanisms of estrogen regulation of bone resorption. J Clin Invest 2000;106:1203-1204
    • (2000) J Clin Invest , vol.106 , pp. 1203-1204
    • Riggs, B.L.1
  • 54
    • 0036436767 scopus 로고    scopus 로고
    • Osteoporosis and the growth hormone-insulin-like growth factor axis
    • Geusens PP, Boonen S. Osteoporosis and the growth hormone-insulin-like growth factor axis. Horm Res 2002;58(Suppl 3):49-55
    • (2002) Horm Res , vol.58 , Issue.SUPPL. 3 , pp. 49-55
    • Geusens, P.P.1    Boonen, S.2
  • 55
    • 1842633629 scopus 로고    scopus 로고
    • IGF-I and testosterone levels as predictors of bone mineral density in healthy, community-dwelling men
    • Rucker D, Ezzat S, Diamandi A, Khosravi J, Hanley DA. IGF-I and testosterone levels as predictors of bone mineral density in healthy, community-dwelling men. Clin Endocrinol 2004;60:491-499
    • (2004) Clin Endocrinol , vol.60 , pp. 491-499
    • Rucker, D.1    Ezzat, S.2    Diamandi, A.3    Khosravi, J.4    Hanley, D.A.5
  • 56
    • 0031948778 scopus 로고    scopus 로고
    • Bone mineral density in prepubertal children with beta-thalassemia: Correlation with growth and hormonal data
    • Soliman AT, El Banna N, Abdel Fattah M, El Zalabani MM, Ansari BM. Bone mineral density in prepubertal children with beta-thalassemia: correlation with growth and hormonal data. Metabolism 1998;47:541-548
    • (1998) Metabolism , vol.47 , pp. 541-548
    • Soliman, A.T.1    El Banna, N.2    Abdel Fattah, M.3    El Zalabani, M.M.4    Ansari, B.M.5
  • 61
    • 0031851068 scopus 로고    scopus 로고
    • The morbidity of bone disease in thalassemia
    • Vichinsky EP. The morbidity of bone disease in thalassemia. Ann NY Acad Sci 1998;850:344-348
    • (1998) Ann NY Acad Sci , vol.850 , pp. 344-348
    • Vichinsky, E.P.1
  • 62
    • 0037346077 scopus 로고    scopus 로고
    • Transferrin receptor-2 polymorphisms and iron overload in transfusion independent b-thalassemia intermedia
    • Ma ES, Lam KK, Chan AY, Ha SY, Au WY, Chan LC. Transferrin receptor-2 polymorphisms and iron overload in transfusion independent b-thalassemia intermedia. Haematologica 2003;88:345-346
    • (2003) Haematologica , vol.88 , pp. 345-346
    • Ma, E.S.1    Lam, K.K.2    Chan, A.Y.3    Ha, S.Y.4    Au, W.Y.5    Chan, L.C.6
  • 63
    • 0024191728 scopus 로고
    • Incidence and treatment of fractures in thalassemia
    • Michelson J, Cohen A. Incidence and treatment of fractures in thalassemia. J Orthop Trauma 1988;2:29-32
    • (1988) J Orthop Trauma , vol.2 , pp. 29-32
    • Michelson, J.1    Cohen, A.2
  • 65
    • 0021200244 scopus 로고
    • Disuse osteoporosis: Physiological aspects
    • Whedon GD. Disuse osteoporosis: physiological aspects. Calcif Tissue Int 1984;36(Suppl 1):146-150
    • (1984) Calcif Tissue Int , vol.36 , Issue.SUPPL. 1 , pp. 146-150
    • Whedon, G.D.1
  • 68
    • 0027477093 scopus 로고
    • Prevention and treatment of osteoporosis
    • Lindsay R. Prevention and treatment of osteoporosis. Lancet 1993;341:801-805
    • (1993) Lancet , vol.341 , pp. 801-805
    • Lindsay, R.1
  • 69
    • 0028998954 scopus 로고
    • Effects of calcitonin therapy on osteoporosis in patients with thalassemia
    • Canatan D, Akar N, Arcasoy A. Effects of calcitonin therapy on osteoporosis in patients with thalassemia. Acta Haematol 1995;93:20-24
    • (1995) Acta Haematol , vol.93 , pp. 20-24
    • Canatan, D.1    Akar, N.2    Arcasoy, A.3
  • 71
    • 12544257260 scopus 로고    scopus 로고
    • Kosarvan M, Zadeh MF, Shahi VK. The bone density of thalassemic patients of Boo Ali Sina hospital, Sari, Iran in 2002; does hydroxyurea help? Pediatr Endocrinol Rev 2004;(Suppl 2):303-308
    • Kosarvan M, Zadeh MF, Shahi VK. The bone density of thalassemic patients of Boo Ali Sina hospital, Sari, Iran in 2002; does hydroxyurea help? Pediatr Endocrinol Rev 2004;(Suppl 2):303-308
  • 73
    • 0032468984 scopus 로고    scopus 로고
    • Bisphosphonates: Mechanisms of action
    • Fleisch H. Bisphosphonates: mechanisms of action. Endocrinol Rev 1998;19:80-100
    • (1998) Endocrinol Rev , vol.19 , pp. 80-100
    • Fleisch, H.1
  • 74
    • 0029886359 scopus 로고    scopus 로고
    • Bisphosphonates: A review of their pharmacokinetic properties
    • Lin JH. Bisphosphonates: a review of their pharmacokinetic properties. Bone 1996;18:75-85
    • (1996) Bone , vol.18 , pp. 75-85
    • Lin, J.H.1
  • 75
    • 1442301556 scopus 로고    scopus 로고
    • Bisphosphonate treatment for multiple myeloma
    • Terpos E, Rahemtulia A. Bisphosphonate treatment for multiple myeloma. Drugs Today 2004;40:29-40
    • (2004) Drugs Today , vol.40 , pp. 29-40
    • Terpos, E.1    Rahemtulia, A.2
  • 76
    • 0032772281 scopus 로고    scopus 로고
    • Diagnosis and management of osteoporosis in postmenopausal women: Clinical guidelines. International Committee for Osteoporosis Clinical Guidelines
    • Meunier PJ, Delmas PD, Eastell R, McClung MR, Papapoulos S, Rizzoli R, Seeman E, Wasnich RD. Diagnosis and management of osteoporosis in postmenopausal women: clinical guidelines. International Committee for Osteoporosis Clinical Guidelines. Clin Ther 1999;21:1025-1044
    • (1999) Clin Ther , vol.21 , pp. 1025-1044
    • Meunier, P.J.1    Delmas, P.D.2    Eastell, R.3    McClung, M.R.4    Papapoulos, S.5    Rizzoli, R.6    Seeman, E.7    Wasnich, R.D.8
  • 78
    • 0346363162 scopus 로고    scopus 로고
    • Quantitative ultrasound of bone and clodronate effects in thalassemia-induced osteoporosis
    • Pennisi P, Pizzarelli G, Spina M, Riccobene S, Fiore CE. Quantitative ultrasound of bone and clodronate effects in thalassemia-induced osteoporosis. J Bone Miner Metab 2003;21:402-408
    • (2003) J Bone Miner Metab , vol.21 , pp. 402-408
    • Pennisi, P.1    Pizzarelli, G.2    Spina, M.3    Riccobene, S.4    Fiore, C.E.5
  • 82
    • 33750591425 scopus 로고    scopus 로고
    • Zoledronic acid for the treatment of thalassemia-induced osteoporosis
    • Mahachoklertwattana P. Zoledronic acid for the treatment of thalassemia-induced osteoporosis. Haematologica 2006;91:1155
    • (2006) Haematologica , vol.91 , pp. 1155
    • Mahachoklertwattana, P.1
  • 83
    • 33748757909 scopus 로고    scopus 로고
    • Zoledronic acid for the treatment of osteoporosis in patients with beta-thalassemia: Results from a single-center, randomized, placebo-controlied trial
    • Voskaridou E, Anagnostopoulos A, Konstantopoulos K, Stoupa E, Spyropoulou E, Kiamouris C, Terpos E. Zoledronic acid for the treatment of osteoporosis in patients with beta-thalassemia: results from a single-center, randomized, placebo-controlied trial. Haematologica 2006;91:1193-1202
    • (2006) Haematologica , vol.91 , pp. 1193-1202
    • Voskaridou, E.1    Anagnostopoulos, A.2    Konstantopoulos, K.3    Stoupa, E.4    Spyropoulou, E.5    Kiamouris, C.6    Terpos, E.7
  • 84
    • 26844534070 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw and bisphosphonates
    • Woo SB, Hande K, Richardson PG. Osteonecrosis of the jaw and bisphosphonates. N Engl L Med 2005;353:99-102
    • (2005) N Engl L Med , vol.353 , pp. 99-102
    • Woo, S.B.1    Hande, K.2    Richardson, P.G.3
  • 85
    • 54349085318 scopus 로고    scopus 로고
    • Continuous improvement of bone mineral density two years post zoledronic acid discontinuation in patients with thalassemia-induced osteoporosis: Long-term follow up of a randomized, placebo-controlled trial
    • in press
    • Voskaridou E, Christoulas D, Konstantinidou M, Tsiftsakis E, Spyropoulou E, Alexakos P, Terpos E. Continuous improvement of bone mineral density two years post zoledronic acid discontinuation in patients with thalassemia-induced osteoporosis: long-term follow up of a randomized, placebo-controlled trial. Haematologica 2008; in press
    • (2008) Haematologica
    • Voskaridou, E.1    Christoulas, D.2    Konstantinidou, M.3    Tsiftsakis, E.4    Spyropoulou, E.5    Alexakos, P.6    Terpos, E.7
  • 87
    • 40549136796 scopus 로고    scopus 로고
    • Continuous increase in erythropoietic activity despite the improvement in bone mineral density by zoledronic acid in patients with thalassemia induced osteoporosis
    • Voskaridou E, Christoulas D, Antoniadou E, Terpos E. Continuous increase in erythropoietic activity despite the improvement in bone mineral density by zoledronic acid in patients with thalassemia induced osteoporosis. Acta Haematol 2008;119:40-44
    • (2008) Acta Haematol , vol.119 , pp. 40-44
    • Voskaridou, E.1    Christoulas, D.2    Antoniadou, E.3    Terpos, E.4
  • 88
    • 0242413030 scopus 로고    scopus 로고
    • Recombinant human parathyroid hormone (1-34) (teriparatide) improves both cortical and cancellous bone structure
    • Jiang Y, Zhao JJ, Mitlak BH, Wang O, Genant HK, Eriksen EF. Recombinant human parathyroid hormone (1-34) (teriparatide) improves both cortical and cancellous bone structure. J Bone Miner Res 2003;18:1932-1941
    • (2003) J Bone Miner Res , vol.18 , pp. 1932-1941
    • Jiang, Y.1    Zhao, J.J.2    Mitlak, B.H.3    Wang, O.4    Genant, H.K.5    Eriksen, E.F.6
  • 90
    • 1642289532 scopus 로고    scopus 로고
    • Gene therapy with human recombinant osteoprotegerin reverses established osteopenia in ovariectomized mice
    • Kostenuik PJ, Bolon B, Morony S, Daris M, Geng Z, Carter C, Sheng J. Gene therapy with human recombinant osteoprotegerin reverses established osteopenia in ovariectomized mice. Bone 2004;34:656-664
    • (2004) Bone , vol.34 , pp. 656-664
    • Kostenuik, P.J.1    Bolon, B.2    Morony, S.3    Daris, M.4    Geng, Z.5    Carter, C.6    Sheng, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.