Gene therapy with human recombinant osteoprotegerin reverses established osteopenia in ovariectomized mice

Bone

Volumn 34, Issue 4, 2004, Pages 656-664

  Kostenuik, Paul J ^a   Bolon, Brad ^a,b   Morony, Sean ^a   Daris, Mark ^a   Geng, Zhaopo ^a   Carter, Christopher ^a   Sheng, Jackie ^a  

^a AMGEN INC   (United States)

^b GEMpath Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; COMPLEMENTARY DNA; RECOMBINANT OSTEOPROTEGERIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE DENSITY; BONE MINERAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG SAFETY; FEMALE; LIVER TOXICITY; METAPHYSIS; MORPHOMETRICS; NONHUMAN; NONVIRAL GENE THERAPY; OSTEOCLAST; OSTEOPENIA; OVARIECTOMY; QUANTITATIVE ANALYSIS; TIBIA;

ANIMALS; BONE DENSITY; BONE DISEASES, METABOLIC; BONE RESORPTION; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; FEMALE; GENE THERAPY; GENETIC VECTORS; GLYCOPROTEINS; HUMANS; LIVER; MICE; OSTEOPROTEGERIN; OVARIECTOMY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; TIBIA; TIME FACTORS;

EID: 1642289532     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2003.12.006     Document Type: Article

References (24)

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