A sequence variation: 713-8delC in the transforming growth factor-beta 1 gene has higher prevalence in osteoporotic women than in normal women and is associated with very low bone mass in osteoporotic women and increased bone turnover in both osteoporotic and normal women

Bone

Volumn 20, Issue 3, 1997, Pages 289-294

  Langdahl, B L ^a   Knudsen, J Y ^a   Jensen, H K ^b   Gregersen, N ^b   Eriksen, E F ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Bone mass; Bone turnover; Osteoporosis; Sequence variations; Transforming growth factor beta 1 (TGF 1)

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; CYTOSINE; HYDROXYPROLINE; ISOLEUCINE; THREONINE; THYMIDINE; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BONE MASS; BONE TURNOVER; CELL INTERACTION; CONTROLLED STUDY; DNA SEQUENCE; EXON; FEMALE; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HYDROXYPROLINE URINE LEVEL; INTRON; LUMBAR SPINE; MAJOR CLINICAL STUDY; NUCLEIC ACID BASE SUBSTITUTION; OSTEOBLAST; OSTEOCLAST; OSTEOPOROSIS; SINGLE STRAND CONFORMATION POLYMORPHISM; SPINE FRACTURE;

ADULT; AGED; AGED, 80 AND OVER; BONE DENSITY; DNA PRIMERS; EXONS; FEMALE; HUMANS; MIDDLE AGED; OSTEOPOROSIS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; SEQUENCE ANALYSIS, DNA; TRANSFORMING GROWTH FACTOR BETA; VARIATION (GENETICS);

EID: 0030999773     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(96)00363-8     Document Type: Article

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