Osteoporosis in β-thalassaemia major patients: Analysis of the genetic background

British Journal of Haematology

Volumn 111, Issue 2, 2000, Pages 461-466

  Mugneret, Francine ^a   Chaffanet, Max ^b   Maynadié, Marc ^a   Guasch, Géraldine ^c   Favre, Bernardine ^a   Casasnovas, Olivier ^a   Birnbaum, Daniel ^b,c   Pébusque, Marie Josèphe ^c  

^a HÔPITAL DU BOCAGE   (France)

^b INSTITUT PAOLI CALMETTES   (France)

^c INSERM   (France)

Author keywords

COLIA1 gene; Osteoporosis; Thalassaemia major; Transforming growth factor beta 1 (TGF 1) gene

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ARTICLE; BETA THALASSEMIA; BLOOD TRANSFUSION; BONE LESION; BONE MALFORMATION; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; FRACTURE; GENETIC ANALYSIS; GENETIC PREDISPOSITION; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; MALE; OSTEOPENIA; OSTEOPOROSIS; PRIORITY JOURNAL;

ADULT; ANALYSIS OF VARIANCE; BETA-THALASSEMIA; BLOOD TRANSFUSION; BONE DENSITY; COLLAGEN; FEMALE; GENE DELETION; GENOTYPE; HUMANS; MALE; OSTEOPOROSIS; POLYMORPHISM, GENETIC; REGRESSION ANALYSIS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0034531861     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02382.x     Document Type: Article

References (28)

1. Transforming growth factor-β1 gene polymorphism, bone turnover and bone mass in Italian postmenopausal women
2. Role of transforming growth factor-beta in bone remodelling
3. Anemia in children with splenomegaly and peculiar changes in bones
4. Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells
5. Abnormal bone metabolism in thalassaemia
6. Reduced bone density and osteoporosis associated with a polymorphic Spl binding site in the collagen type α1 gene
7. Bone mineral density, collagen type I α 1 genotypes and bone turnover in premenopausal women with diabetes mellitus
8. Nonassociation of oestrogen receptor genotypes with bone mineral density and estrogens responsiveness to hormone replacement therapy in Korean postmenopausal women
9. High prevalence of low bone mass in thalassaemia major
10. The diagnosis of osteoporosis
11. Association of bone mineral density with polymorphism of the oestrogen receptor gene
12. Heritable and lifestyle determinants of bone mineral density
13. A sequence variation: 713-8delC in transforming growth factor-beta 1 gene has higher prevalence in osteoporotic women than in normal women and is associated with very low bone mass in osteoporotic and normal women
14. An Spl binding site polymorphism in the COLIA1 gene predicts osteoporotic fractures in both men and women
15. Polymorphism of the calcitonin receptor gene are associated with bone mineral density in postmenopausal Italian women
16. Prediction of bone density from vitamin D receptor alleles
17. The beta-thalassemia
18. Vitamin D receptor alleles and osteoporosis: A contrasting view
19. Genetic determinants of bone mass inadults: A twin study
20. Bone disease in β-thalassaemia
21. Genetic determinants of bone mass in adult women: A revaluation of the twin model and the potential importance of gene interaction on heritability estimates
22. Family history of osteoporosis and bone mineral density at the axial skeleton: The Rancho Bernardo study
23. Relation of alleles of the collagen type I α 1 gene to bone density and the risk of osteoporotic fractures in postmenopausal women
24. The morbidity of bone disease in thalassemia
25. Bone disease in β-thalassaemia major
26. Genetic and acquired predisposing factors and treatment of osteoporosis in thalassaemia major
27. Association of a polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to osteoporosis in postmenopausal Japanese women