Mutant γPKC found in spinocerebellar ataxia type 14 induces aggregate-independent maldevelopment of dendrites in primary cultured Purkinje cells

Neurobiology of Disease

Volumn 33, Issue 2, 2009, Pages 260-273

  Seki, Takahiro ^a   Shimahara, Takayuki ^a   Yamamoto, Kazuhiro ^a   Abe, Nana ^a   Amano, Taku ^a   Adachi, Naoko ^b   Takahashi, Hideyuki ^b   Kashiwagi, Kaori ^b   Saito, Naoaki ^b   Sakai, Norio ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b KOBE UNIVERSITY   (Japan)

Author keywords

PKC; Aggregate formation; Dendrites; FRAP; Missense mutation; Oligomer formation; Purkinje cells; Spinocerebellar ataxia type 14 (SCA14); Translocation

Indexed keywords

MUTANT PROTEIN; PROTEIN KINASE C GAMMA; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CELL AGGREGATION; CELL CULTURE; CELL DEGENERATION; CELL MATURATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DENDRITIC CELL; DISEASE CLASSIFICATION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE EXPRESSION; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; SPINOCEREBELLAR DEGENERATION; SYNAPSE; ANIMAL; APOPTOSIS; DENDRITE; DENDRITIC SPINE; GENETICS; HUMAN; METABOLISM; MOUSE; PHYSIOLOGY; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DENDRITES; DENDRITIC SPINES; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GREEN FLUORESCENT PROTEINS; HUMANS; MICE; MUTANT PROTEINS; MUTATION, MISSENSE; PROTEIN KINASE C; PURKINJE CELLS; RECOMBINANT FUSION PROTEINS; SPINOCEREBELLAR ATAXIAS; SYNAPSES; TRANSFECTION;

EID: 58149490769     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2008.10.013     Document Type: Article

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