Acute and chronic effects of intravitreally injected β-amyloid on the neurotransmitter system in the retina

Toxicology

Volumn 256, Issue 1-2, 2009, Pages 92-100

  Aruoma, Okezie I ^a   Jen, Sheila S M ^b   Watts, Helena R ^b   George, Joseph ^b   Gentleman, Stephen M ^c   Anderson, Peter J B ^b   Jen, Ling Sun ^b  

^a TOURO COLLEGE   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c Division of Neuroscience and Mental Health ^*  (United Kingdom)

Author keywords

Alzheimer's disease; Amyloid beta; Choline acetyltransferase (ChAT); Gamma aminobutyric acid (GABA) and 5 tryptamine hydroxylase systems (5 TryptH); Neurotransmitter systems

Indexed keywords

4 AMINOBUTYRIC ACID; 5 TRYPTAMINE HYDROXYLASE; ACETYLCHOLINE; AMYLOID BETA PROTEIN; CATECHOLAMINE; CHOLINE ACETYLTRANSFERASE; NEUROTRANSMITTER; SEROTONIN; TRYPTAMINE DERIVATIVE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CATECHOLAMINERGIC SYSTEM; CELL DENSITY; CELL LOSS; CENTRAL NERVOUS SYSTEM; CHOLINERGIC SYSTEM; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; FEMALE; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA; RETINA NERVE CELL;

AMYLOID BETA-PROTEIN; ANIMALS; CHOLINE O-ACETYLTRANSFERASE; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MICROINJECTIONS; NERVE DEGENERATION; NEUROGLIA; NEUROTRANSMITTER AGENTS; PARASYMPATHETIC NERVOUS SYSTEM; PHOTORECEPTOR CELLS, VERTEBRATE; RATS; RATS, SPRAGUE-DAWLEY; RETINA; RETINAL GANGLION CELLS; TYROSINE 3-MONOOXYGENASE; VITREOUS BODY;

EID: 58149471506     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.11.007     Document Type: Article

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