Genetic perturbation of the putative cytoplasmic membrane-proximal salt bridge aberrantly activates α4 integrins

Blood

Volumn 112, Issue 13, 2008, Pages 5007-5015

  Imai, Yoichi ^a,b   Park, Eun Jeong ^a,b   Peer, Dan ^a,b   Peixoto, António ^a,b   Cheng, Guiying ^a,b   Von Andrian, Ulrich H ^a,b   Carman, Christopher V ^a   Shimaoka, Motomu ^a,b,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CENTER FOR BLOOD RESEARCH   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 BETA7 INTEGRIN; ALPHA4 INTEGRIN; ARGININE; INTEGRIN; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; SODIUM CHLORIDE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4; FIBRINOGEN RECEPTOR; INTEGRIN ALPHA4BETA7;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CELL HOMING; CELL MEMBRANE; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM; GENETICS; GERM LINE; INTESTINE; LIGAND BINDING; LYMPHOCYTE; LYMPHOCYTE MIGRATION; MOUSE; MUTATION; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; UPREGULATION; ANIMAL; CHEMISTRY; CYTOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE;

ANIMALS; CELL ADHESION; CHEMOTAXIS, LEUKOCYTE; CONSERVED SEQUENCE; GERM-LINE MUTATION; INTEGRIN ALPHA4; INTEGRIN ALPHA4BETA1; INTEGRINS; LYMPHOCYTES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN CONFORMATION;

EID: 58149393174     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-03-144543     Document Type: Article

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