Increased lymphocyte trafficking to colonic microvessels is dependent on MAdCAM-1 and C-C chemokine mLARC/CCL20 in DSS-induced mice colitis

Clinical and Experimental Immunology

Volumn 139, Issue 3, 2005, Pages 421-428

  Teramoto, K ^a   Miura, Soichiro ^b   Tsuzuki, Y ^b   Hokari, R ^b   Watanabe, C ^a   Inamura, T ^a   Ogawa, T ^a   Hosoe, N ^a   Nagata, H ^a   Ishii, H ^a   Hibi, T ^a  

^a KEIO UNIVERSITY   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

CC chemokine receptor 6 (CCR6); Dextran sodium sulphate; Inflammatory bowel disease; Lymphocyte migration; MAdCAM 1; Murine liver and activation regulated chemokine (mLARC CCL20); VCAM 1

Indexed keywords

CHEMOKINE RECEPTOR CCR6; DEXTRAN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MONOCLONAL ANTIBODY; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; SODIUM SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DESENSITIZATION; LEUKOCYTE ADHERENCE; LIVER; LYMPHOCYTE TRANSFER; MICROVASCULATURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; B-LYMPHOCYTES; CELL ADHESION; CELL ADHESION MOLECULES; CELL MOVEMENT; CHEMOKINES, CC; CHRONIC DISEASE; COLITIS; COLON; DEXTRAN SULFATE; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MACROPHAGE INFLAMMATORY PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICROCIRCULATION; MODELS, ANIMAL; MUCOPROTEINS; RECEPTORS, CHEMOKINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES;

EID: 20044376669     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2004.02716.x     Document Type: Article

References (29)

1. Briskin M, Winsor-Hines D, Shyjan A et al. Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. Am J Pathol 1997; 151:97-110.
2. Fujimori H, Miura S, Koseki S et al. Intravital observation of adhesion of lamina propria lymphocytes to microvessels of small intestine in mice. Gastroenterology 2002; 122:734-44.
3. Souza HS, Elia CC, Spencer J, MacDonald T. Expression of lymphocyte-endothelial receptor-ligand pairs, α4β7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease. Gut 1999; 45:856-63.
4. Kato S, Hokari R, Matsuzaki K et al. Amelioration of murine experimental colitis by inhibition of mucosal addressin cell adhesion molecule-1. J Pharmacol Exp Ther 2000; 295:183-9.
5. Hokari R, Kato S, Matsuzaki K et al. Involvement of mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in the pathogenesis of granulomatous colitis in rats. Clin Exp Immunol 2001; 126:259-65.
6. Nakamura S, Ohtani H, Watanabe Y, Fukushima K, Matsumoto T, Kitano A, Kobayashi K, Nagura H. In situ expression of the cell adhesion molecule in inflammatory bowel disease. Evidence of immunologic activation of vascular endothelial cells. Laboratory Invest 1993; 59:77-85.
7. Jones SC, Banks RE, Haidar A, Gearing AJ, Hemingway IK, Ibbotson SH, Dixon MF, Axon AT. Adhesion molecules in inflammatory bowel disease. Gut 1995; 36:724-30.
8. Shigematsu T, Specian RD, Wolf RE, Grisham MB, Granger DN. MAdCAM mediates lymphocyte-endothelial cell adhesion in a murine model of chronic colitis. Am J Physiol Gastrointest Liver Physiol 2001; 281:G1309-15.
9. Dieu MC, Vanbervliet B, Vicari A et al. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J Exp Med 1998; 188:373-86.
10. Tanaka Y, Imai T, Baba M, Ishikawa I, Uehira M, Nomiyama H, Yoshie O. Selective expression of liver and activation-regulated chemokine (LARC) in intestinal epithelium in mice and humans. Eur J Immunol 1999; 29:633-42.
11. Liao F, Rabin RL, Smith CS, Sharma G, Nutman TB, Farber JM. CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3 alpha. J Immunol 1999; 162:186-94.
12. Cook DN, Prosser DM, Forster R et al. CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue. Immunity 2000; 12:495-503.
13. Campbell JJ, Hedrick J, Zlotnik A, Siani MA, Thompson DA, Butcher EC. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 1998; 279:381-4.
14. Miura S, Tsuzuki Y, Fukumura D et al. Intravital demonstration of sequential migration process of lymphocyte subpopulations in rat Peyer's patches. Gastroenterology 1995; 109:1113-23.
15. Watanabe C, Miura S, Hokari R et al. Spatial heterogeneity of TNF-alpha-induced T cell migration to colonic mucosa is mediated by MAdCAM-1 and VCAM-1. Am J Physiol Gastrointest Liver Physiol 2002; 283:G1379-87.
16. Hosoe N, Miura S, Watanabe C et al. Demonstration of functional role of TECK/CCL25 in T lymphocyte-endothelium interaction in inflamed and uninflamed intestinal mucosa. Am J Physiol Gastrointest Liver Physiol 2004; 286:G458-66.
17. Hokari R, Kato S, Matsuzaki K et al. Reduced sensitivity of inducible nitric oxide synthase-deficient mice to chronic colitis. Free Radic Biol Med 2001; 31:153-63.
18. Soriano A, Salas A, Salas A et al. VCAM-1, but not ICAM-1 or MAdCAM-1, immunoblockade ameliorates DSS-induced colitis in mice. Laboratory Invest 2000; 80:1541-51.
19. Burns RC, Rivera-Nieves J, Moskaluk CA, Matsumoto S, Cominelli F, Ley K. Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice. Gastroenterology 2001; 121:1428-36.
20. Warnock RA, Campbell JJ, Dorf ME, Matsuzawa A, McEvoy LM, Butcher EC. The role of chemokines in the microenvironmental control of T versus B cell arrest in Peyer's patch high endothelial venules. J Exp Med 2000; 191:77-88.
21. Farstad IN, Halstensen TS, Lazarovits AI, Norstein J, Fausa O, Brandtzaeg P. Human intestinal B-cell blasts and plasma cells express the mucosal homing receptor integrin alpha 4 beta 7. Scand J Immunol 1995; 42:662-72.
22. Scheerens H, Hessel E, de Waal-Malefyt R, Leach MW, Rennick D. Characterization of chemokines and chemokine receptors in two murine models of inflammatory bowel disease. IL-10-/- mice and Rag-2-/- mice reconstituted with CD4+CD45RBhigh T cells. Eur J Immunol 2001; 31:1465-74.
23. Iwasaki A, Kelsall BL. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP) -3alpha, MIP-3beta, and secondary lymphoid organ chemokine. J Exp Med 2000; 191:1381-94.
24. Izadpanah A, Dwinell MB, Eckmann L, Varki NM, Kangnoff MF. Regulated MIP-3alpha/CCL20 production by human intestinal epithelium: mechanism for modulating mucosal immunity. Am J Physiol Gastrointest Liver Physiol 2001; 280:G710-9.
25. Kwon JH, Keates S, Bassani L, Mayer LF, Keates AC. Colonic epithelial cells are a major site of macrophage inflammatory protein 3α (MIP-3α) production in normal colon and inflammatory bowel disease. Gut 2002; 51:818-26.
26. Middleton J, Neil S, Wintle J et al. Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell 1997; 91:385-95.
27. Hromas R, Gray PW, Chantry D et al. Cloning and characterization of exodus, a novel beta-chemokine. Blood 1997; 89:3315-22.
28. Kriehuber E, Breiteneder-Geleff S, Groeger M, Soleiman A, Schoppmann SF, Stingl G, Kerjaschki D, Maurer D. Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J Exp Med 2001; 194:797-808.
29. Fitzhugh DJ, Naik S, Caughman SW, Hwang ST. C-C chemokine receptor 6 is essential for arrest of a subset of memory T cells on activated dermal microvascular endothelial cells under physiologic flow conditions in vitro. J Immunol 2000; 165:6677-81.