Autophagy contributes to degradation of Hirano bodies

Autophagy

Volumn 5, Issue 1, 2009, Pages 44-51

  Kim, Dong Hwan ^a   Davis, Richard C ^a   Furukawa, Ruth ^a   Fechheimer, Marcus ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Actin; Autophagy; Dictyostelium; Hirano bodies; Mammalian cell culture; Neuropathology; Proteasome

Indexed keywords

ADENINE; BIOLOGICAL MARKER; DISCOIDIN; LACTACYSTIN; PROTEASOME;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL CULTURE; CELL GROWTH; CELL STRUCTURE; CLEARANCE; CONTROLLED STUDY; CULTURE MEDIUM; DICTYOSTELIUM; ELECTRON MICROSCOPY; EXOCYTOSIS; HIRANO BODY; HUMAN; HUMAN CELL; MAMMAL CELL; MEMBRANE VESICLE; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOUSE; MUTANT; NONHUMAN; PHAGOSOME; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN STRUCTURE; WILD TYPE;

DICTYOSTELIUM; MAMMALIA;

EID: 58149389727     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.5.1.7228     Document Type: Article

References (51)

1. Hirano A. Hirano bodies and related neuronal inclusions. Neuropathol Appl Neurobiol 1994; 20:3-11.
2. Lass R, Hagel C. Hirano bodies and chronic alcoholism. Neuropath Appl Neurobiol 1994; 20:12-21.
3. Gibson PH, Tomlinson BE. Numbers of Hirano bodies in the hippocampus of normal and demented people with Alzheimer's disease. J Neurol Sci 1977; 33:199-206.
4. Goldman JE. The association of actin with Hirano bodies. J Neuropathol Exp Neurol 1983; 42:146-52.
5. Galloway PG, Perry G, Gambetti P. Hirano body filaments contain actin and actin-associated proteins. J Neuropathol Exp Neurol 1987; 46:185-99.
6. Munoz DG, Wang D, Greenberg BD. Hirano bodies accumulate C-terminal sequences of beta-amyloid precursor protein (beta-APP) epitopes. J Neuropathol Exp Neurol 1993; 52:14-21.
7. Ha S, Furukawa R, Fechheimer M. Association of the carboxyl-terminal domain of the amyloid-β precursor protein with Hirano bodies reduces activation of transcription and initiation of apoptosis. Submitted for publication 2008.
8. Galloway PG, Perry G, Kosik KS, Gambetti P. Hirano bodies contain tau protein. Brain Res 1987; 403:337-40.
9. Peterson C, Kress Y, Vallee R, Goldman JE. High molecular weight microtubule-associated proteins bind to actin lattices (Hirano bodies). Acta Neuropathol 1988; 77:168-74.
10. Davis RC, Furukawa R, Fechheimer M. A cell culture model for investigation of Hirano bodies. Acta Neuropathol 2008; 115:205-17.
11. Goldberg AL. Functions of the proteasome: From protein degradation and immune surveillance to cancer therapy. Biochem Soc Trans 2007; 35:12-7.
12. Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature 2008; 451:1069-75.
13. Maselli AG, Davis R, Furukawa R, Fechheimer M. Formation of Hirano bodies in Dictyostelium and mammalian cells induced by expression of a modified form of an actin cross-linking protein. J Cell Sci 2002; 115:1939-52.
14. Maselli AG, Furukawa R, Thomson SAM, Davis RC, Fechheimer M. Formation of Hirano bodies induced by expression of an actin cross-linking protein with a gain of function mutation. Eucaryot Cell 2003; 2:778-87.
15. Otto GP, Wu MY, Kazgan N, Anderson OR, Kessin RH. Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum. J Biol Chem 2003; 278:17636-45.
16. Otto GP, Wu MY, Kazgan N, Anderson OR, Kessin RH. Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum. J Biol Chem 2004; 278:17636-45.
17. Tekinay T, Wu MY, Otto GP, Anderson OR, Kessin RH. Function of the Dictyostelium discoideum Atg1 kinase during autophagy and development. Eukaryot Cell 2006; 5:1797-806.
18. Gibson PH. Light and electron microscopic observations on the relationship between Hirano bodies, neuron and glial perikarya in the human hippocampus. Acta Neuropathol 1978; 42:165-71.
19. Schochet SS Jr, McCormick WF. Ultrastructure of Hirano bodies. Acta Neuropathol 1972; 21:50-60.
20. Izumiyama N, Ohtsubo K, Tachikawa T, Nakamura H. Elucidation of three-dimensional ultrastructure of Hirano bodies by the quick-freeze, deep-etch and replica method. Acta Neuropathol 1991; 81:248-54.
21. Tomonaga M. Ultrastructure of Hirano bodies. Acta Neuropathol 1974; 28:365-6.
22. Blusch J, Morandini P, Nellen W. Transcriptional regulation by folate: Inducible gene expression in Dictyostelium transformants during growth and early development. Nucl Acids Res 1992; 20:6235-8.
23. Kirkitadze MD, Bitan G, Teplow DB. Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies. J Neurosci Res 2002; 69:567-77.
24. Rubinsztein DC. The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 2006; 443:780-6.
25. Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, Mizushima N. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441:885-9.
26. Komatsu M, Waguri S, Chiba T, Murata S, Iwata J-i, Tanida I, Ueno T, Koike M, Uchiyama Y, Kominami E, Tanaka K. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441:880-4.
27. Kabuta T, Suzuki Y, Waka K. Degradation of amyotrophic lateral sclerosis-linked mutant Cu,Zn-superoxide dismutase proteins by macroautophagy. J Biol Chem 2006; 281:30524-33.
28. Ravikumar B, Duden B, Rubinsztein DC. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Human Mol Genet 2002; 11:1107-17.
29. Webb JL, Ravikumar B, Atkins J, Skepper JN, Rubinsztein DC. Alpha-synuclein is degraded by both autophagy and the proteasome. J Biol Chem 2003; 278:25009-13.
30. Kamimoto T, Shoji S, Hidvegi T, Mizushima N, Umebayashi K, Perlmutter DH, Yoshimori T. Intracellular inclusions containing mutant alpha1-antitrypsin Z are propagated in the absence of autophagic activity. J Biol Chem 2006; 281:4467-76.
31. Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS, Goldstein LSB. Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science 2005; 307:1282-8.
32. Ravikumar B, Acevedo-Arozena A, Imarisio S, Berger Z, Vacher C, O'Kane CJ, Brown SDM, Rubinsztein DC. Dynein mutations impair autophagic clearance of aggregate-prone proteins. Nat Genetics 2005; 37:771-6.
33. Johnston JA, Ward CL, Kopito RR. Aggresomes: a cellular response to misfolded proteins. J Cell Biol 1998; 143:1883-98.
34. Lázaro-Diéguez F, Aguado C, Mato E, Sánchez-Ruiz Y, Esteban I, Alberch J, Knecht E, Egea G. Dynamics of an F-actin aggresome generated by the actin-stabilizing toxin jasplakinolide. J Cell Sci 2008; 121:1415-25.
35. Lázaro-Diéguez F, Knecht E, Egea G. Clearance of a Hirano body-like F-actin aggresome generated by jasplakinolide. Autophagy 2008; 4:717-20.
36. Reggiori F, Monastyrska I, Shintani T, Klionsky DJ. The actin cytoskeleton is required for selective types of autophagy, but nonspecific autophagy, in the yeast Saccharomyces cerevisiae. Mol Biol Cell 2005; 16:5843-56.
37. Monastyrska I, Shintani T, Klionsky DJ, Reggiori F. Atg11 directs autophagosome cargoes to the PAS along actin cables. Autophagy 2006; 2:119-21.
38. Monastyrska I, He C, Geng J, Hoppe AD, Klionsky DJ. Arp2 links autophagic machinery with the actin cytoskeleton. Mol Biol Cell 2008; 19:1962-75.
39. Goebel HH. The neuronal ceroid-lipofuscinoses. Semin Pediatr Neurol 1996; 3:270-8.
40. Mole SE, Williams RE, Goebel HH. Correlations between genotype, ultrastructural morphology and clinical phenotype in the neuronal ceroid lipofuscinoses. Neurogenetics 2005; 6:107-26.
41. Anderson GW, Smith VV, Brooke I, Malone M, Sebire NJ. Diagnosis of neuronal ceroid lipofuscinosis (Batten disease) by electron microscopy in peripheral blood specimens. Ultrastruct Pathol 2006; 30:373-8.
42. Haltia M. The neuronal ceroid lipofuscinoses: From past to present. Biochim Biophys Acta 2006; 1762:850-6.
43. Lim RWL, Furukawa R, Fechheimer M. Evidence of intramolecular regulation of the Dictyostelium discoideum 34,000 dalton F-actin bundling protein. Biochemistry 1999; 38:16323-32.
44. Maniatis T, Fritsch EF, Sambrook J. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor: Cold Spring Harbor Press 1982.
45. Furukawa R, Maselli AG, Thomson SAM, Lim RW-L, Stokes JV, Fechheimer M. Calcium Regulation of actin cross-linking is important for function of the actin cytoskeleton in Dictyostelium. J Cell Sci 2003; 116:187-96.
46. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC. Measurement of protein using bicinchoninic acid. Anal Biochem 1985; 150:76-85.
47. Furukawa R, Butz S, Fleischmann E, Fechheimer M. The Dictyostelium discoideum 30,000 dalton protein contributes to phagocytosis. Protoplasma 1992; 169:18-27.
48. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76:4350-4.
49. Loomis WF. Sensitivity of Dictyostelium discoideum to nucleic acid analogues. Exp Cell Res 1971; 64:484-6.
50. Fechheimer M. The Dictyostelium discoideum 30,000-dalton protein is an actin filament-bundling protein that is selectively present in filopodia. J Cell Biol 1987; 104:1539-51.
51. Kisselev AF, Goldberg AL. Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates. Meth Enzymol 2005; 398:364-78.