A cell culture model for investigation of Hirano bodies

Acta Neuropathologica

Volumn 115, Issue 2, 2008, Pages 205-217

  Davis, Richard C ^a   Furukawa, Ruth ^a   Fechheimer, Marcus ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Actin cytoskeleton; Hirano bodies; In vitro model; Mammalian cell culture; Microscopy; Neuropathology

Indexed keywords

ACTIN FILAMENT; AGING; ANIMAL CELL; ARTICLE; BIOLOGICAL MODEL; BODY COMPOSITION; BRAIN DISEASE; CARBOXY TERMINAL SEQUENCE; DEGENERATIVE DISEASE; EOSINOPHIL; HIPPOCAMPUS; HIRANO BODY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LAMELLAR BODY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; STRUCTURE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ACTINS; ANIMALS; CELL LINE; DICTYOSTELIUM; HUMANS; INCLUSION BODIES; MICROFILAMENT PROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; PEPTIDES; TRANSFECTION;

EID: 38349002996     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00401-007-0275-9     Document Type: Article

References (67)

1. Adamec E, Yang F, Cole GM, Nixon RA (2001) Multiple-label immunocytochemistry for the evaluation of nature of cell death in experimental models of neurodegeneration. Brain Res Brain Res Protoc 7:193-202
2. Asai DJ, Thompson WC, Wilson L, Dresden CF, Schulman H, Purich DL (1985) Microtubule-associated proteins (MAPs): A monoclonal antibody to MAP 1 decorates microtubules in vitro but stains stress fibers and not microtubules in vivo. Proc Natl Acad Sci USA 82:1434-1438
3. Atsumi T, Yamamura Y, Sato T, Ikuta F (1980) Hirano bodies in the axon of peripheral nerves in a case with progressive external ophthalmoplegia with multisystemic involvements. Acta Neuropathol (Berl) 49:95-100
4. Cartier L, Galvez S, Gajdusek DC (1985) Familial clustering of the ataxic form of Creutzfeldt-Jakob disease with Hirano bodies. J Neurol Neurosurg Psychiatry 48:234-238
5. David-Ferreira JF, David-Ferreira KL, Gibbs CJJ, Morris JA (1968) Scrapie in mice. Ultrastructural observations in the cerebral cortex. Proc Soc Exp Biol Med 127:313-320
6. Dhingra V, Li Q, Allison AB, Stallknecht DE, Fu ZF (2005) Proteomic profiling and neurodegeneration in West-Nile-Virus-Infected neurons. J Biomed Biotechnol 2005(3):271-279
7. Dravid SM, Murray TF (2004) Spontaneous synchronized calcium oscillations in neocortical neurons in the presence of physiological [Mg(2+)]: Involvement of AMPA/kainite and metabotropic glutamate receptors. Brain Res 1006:8-17
8. Fernandez R, Fernandez JM, Cervera C, Teijeira S, Teijeiro A, Dominguez C, Navarro C (1999) Adult glycogenosis II with paracrystalline mitochondrial inclusions and Hirano bodies in skeletal muscle. Neuromuscul Disord 9:136-143
9. Field EJ, Mathews JD, Raine CS (1969) Electron microscopic observations on the cerebellar cortex in kuru. J Neurol Sci 8:209-224
10. Field EJ, Narang HK (1972) An electron-microscopic study of scrapie in the rat: Further observations on "inclusion bodies" and virus-like particles. J Neurol Sci 17:347-364
11. Fulga TA, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB (2007) Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nat Cell Biol 9:139-148
12. Furukawa R, Butz S, Fleischmann E, Fechheimer M (1992) The Dictyostelium discoideum 30,000 dalton protein contributes to phagocytosis. Protoplasma 169:18-27
13. Furukawa R, Fechheimer M (1997) The structure, function, and assembly of actin filament bundles. Int Rev Cytol 175:29-90
14. Galloway PG, Perry G, Gambetti P (1987) Hirano body filaments contain actin and actin-associated proteins. J Neuropathol Exp Neurol 46:185-199
15. Galloway PG, Perry G, Kosik KS, Gambetti P (1987) Hirano bodies contain tau protein. Brain Res 403:337-340
16. Galvan V, Gorostiza OF, Banwait S, Ataie M, Logvinova AV, Sitaraman S, Carlson E, Sagi SA, Chevallier N, Jin K, Greenberg DA, Bredesen DE (2006) Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of asp 664. Proc Natl Acad Sci USA 103:7130-7135
17. Galvin JE, Lee VM, Schmidt ML, Tu PH, Iwatsubo T, Trojanowski JQ (1999) Pathobiology of the Lewy body. Adv Neurol 80:313-324
18. Gambetti P, Schecket G, Ghetti B, Hirano A, Dahl D (1983) Neurofibrillary changes in human brain: An immunocytochemical study with a neurofilament antiserum. J Neuropathol Exp Neurol 42:69-79
19. Gessaga EC, Anzil AP (1975) Rod-shaped filamentous inclusions and other ultrastructural features in a cerebellar astrocytoma. Acta Neuropathol (Berl) 33:119-127
20. Gibson PH, Tomlinson BE (1977) Numbers of Hirano bodies in the hippocampus of normal and demented people with Alzheimer's disease. J Neurol Sci 33:199-206
21. Goedert M (1999) Filamentous nerve cell inclusions in neurodegenerative diseases: Tauopathies and alpha-synucleinopathies. Philos Trans R Soc Lond B Biol Sci 354:1101-1118
22. Goldman JE (1983) The association of actin with Hirano bodies. J Neuropathol Exp Neurol 42:146-152
23. Hirano A, Dembitzer HM, Kurland LT, Zimmerman HM (1968) The fine structure of some intraganlionic alterations. J Neuropathol Exp Neurol 27:167-182
24. Hirano A, Demblitzer HM (1976) Eosinophilic rod-like structure in myelinated fibres of hamster spinal roots. Neuropathol Appl Neurobiol 2:225-232
25. Hirano A (1994) Hirano bodies and related neuronal inclusions. Neuropathol Appl Neurobiol 20:3-11
26. Hirano A (2005) The role of electron microscopy in neuropathology: A personal historical note. Acta Neuropathol (Berl) 109:115-123
27. Izumiyama N, Ohtsubo K, Tachikawa T, Nakamura H (1991) Elucidation of three-dimensional ultrastructure of Hirano bodies by the quick-freeze, deep-etch and replica method. Acta Neuropathol (Berl) 81:248-254
28. Johns JA, Brock AM, Pardee JD (1988) Colocalization of F-actin and 34-kilodalton actin bundling protein in Dictyostelium and cultured fibroblasts. Cell Motil Cytoskeleton 9:205-218
29. Johnston JA, Ward CL, Kopito RR (1998) Aggresomes: A cellular response to misfolded proteins. J Cell Biol 143:1883-1898
30. Jordan-Sciutto K, Dragich J, Walcott D, Bowser R (1998) The presence of FAC1 protein in Hirano bodies. Neuropathol Appl Neurobiol 24:359-366
31. Kopito RR (2000) Aggresomes, inclusion bodies, and protein aggregation. Trends Cell Biol 10:524-530
32. Laas R, Hagel C (1994) Hirano bodies and chronic alcoholism. Neuropathol Appl Neurobiol 20:12-21
33. Lee H-g, Ueda M, Miyamoto Y, Yoneda Y, Perry G, Smith MA, Zhu X (2006) Aberrant localization of importin a1 in hippocampal neurons in Alzheimer disease. Brain Res 1124:1-4
34. Lee SC, Zhao ML, Hirano A, Dickson DW (1999) Inducible nitric oxide synthase immunoreactivity in the Alzheimer disease hippocampus: association with Hirano bodies, neurofibrillary tangles, and senile plaques. J Neuropathol Exp Neurol 58:1163-1169
35. Lim RWL, Furukawa R, Eagle S, Cartwright RC, Fechheimer M (1999) Three distinct F-actin binding sites in the Dictyostelium discoideum 34,000 dalton actin bundling protein. Biochemistry 38:800-812
36. Lim RWL, Furukawa R, Fechheimer M (1999) Evidence of intramolecular regulation of the Dictyostelium discoideum 34,000 dalton F-actin Bundling Protein. Biochemistry 38:16323-16332
37. Maciver SK, Harrington CR (1995) Two actin binding proteins, actin depolymerizing factor and cofilin, are associated with Hirano bodies. Neuroreport 6:1985-1988
38. Maselli AG, Davis R, Furukawa R, Fechheimer M (2002) Formation of Hirano bodies in Dictyostelium and mammalian cells induced by expression of a modified form of an actin cross-linking protein. J Cell Sci 115:1939-1952
39. Maselli AG, Furukawa R, Thomson SAM, Davis RC, Fechheimer M (2003) Formation of Hirano bodies induced by expression of an actin cross-linking protein with a gain of function mutation. Eukaryot Cell 2:778-787
40. Mitake S, Ojika K, Katada E, Otsuka Y, Matsukawa N, Fujimori O (1995) Accumulation of hippocampal cholinergic neurostimulating peptide (HCNP)- related components in Hirano bodies. Neuropathol Appl Neurobiol 21:35-40
41. Mitake S, Katada E, Otsuka Y, Matsukawa N, Iwase T, Tsugu T, Fujimori O, Ojika K (1996) Possible implication of hippocampal cholinergic neurostimulating peptide (HCNP)-related components in Hirano body formation. Neuropathol Appl Neurobiol 22:440-445
42. Mitake S, Ojika K, Hirano A (1997) Hirano bodies and Alzheimer's disease. Kaohsiung J Med Sci 13:10-18
43. Munoz DG, Wang D, Greenberg BD (1993) Hirano bodies accumulate C-terminal sequences of beta-amyloid precursor protein (beta-APP) epitopes. J Neuropathol Exp Neurol 52:14-21
44. Nagara H, Yajima K, Suzuki K (1980) An ultrastructural study on the cerebellum of the brindled mouse. Acta Neuropathol (Berl) 52:41-50
45. Novak KD, Peterson MD, Reedy MC, Titus MA (1995) Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosis. J Cell Biol 131:1205-1221
46. Ogata J, Budzilovich GN, Cravioto H (1972) A study of rod-like structures (Hirano bodies) in 240 normal and pathological brains. Acta Neuropathol (Berl) 21:61-67
47. Okamoto K, Hirai S, Hirano A (1982) Hirano bodies in myelinated fibers of hepatic encephalopathy. Acta Neuropathol (Berl) 58:307-310
48. Orr HT (2001) Beyond the Q's in the polyglutamine diseases. Genes Dev 15:925-932
49. Peress NS, Perillo E (1995) Differential expression of TFG Beta 1, 2, and 3 isotypes in Alzheimer's disease: A comparative immunohistochemical study with cerebral infarction, aged human and mouse control brains. J Neuropathol Exp Neurol 54:802-811
50. Peterson C, Kress Y, Vallee R, Goldman JE (1988) High molecular weight microtubule-associated proteins bind to actin lattices (Hirano bodies). Acta Neuropathol (Berl) 77:168-174
51. Previll LA, Crosby ME, Castellani RJ, Bowser R, Perry G, Smith MA, Zhu X (2007) Increased Expression of p130 in Alzheimer Disease. Neurochem Res 32:639-644
52. Renkawek K, Bosman GJ, de Jong WW (1994) Expression of small heat shock protein hsp 27 in reactive gliosis in Alzheimer disease and other types of dementia. Acta Neuropathol (Berl) 87:511-519
53. Rodriguez LG, Wu X, Guan JL (2005) Wound-healing assay. Methods Mol Biol 294:23-29
54. Rossiter JP, Anderson LL, Yang F, Cole GM (2000) Caspase-cleaved actin (fractin) immunolabelling of Hirano bodies. Neuropathol Appl Neurobiol 26:342-346
55. Saganich MJ, Schroeder BE, Galvan V, Bredesen DE, Koo EH, Heinemann SF (2006) Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require c-terminal cleavage of APP. J Neurosci 26:13428-13436
56. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning, a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
57. Schmidt ML, Lee VM, Trojanowski JQ (1989) Analysis of epitopes shared by Hirano bodies and neurofilament proteins in normal and Alzheimer's disease hippocampus. Lab Invest 60:513-522
58. Schochet SS Jr, Lampert PW, Lindenberg R (1968) Fine structure of the Pick and Hirano bodies in a case of Pick's disease. Acta Neuropathol (Berl) 11:330-337
59. Schochet SS Jr, McCormick WF (1972) Ultrastructure of Hirano bodies. Acta Neuropathol (Berl) 21:50-60
60. Selkoe DJ (1998) The cell biology of b-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol 8:447-453
61. Setoguti T, Esumi H, Shimizu T (1974) Specific organization of intracytoplasmic filaments in the dog testicular interstitial cell. Cell Tissue Res 148:493-497
62. Shao CY, Crary JF, Rao C, Sacktor TC, Mirra SS (2006) Atypical protein kinase C in neurodegnerative disease II: PKC i/l in tauophathies and a-synucleinophathies. J Neuropathol Exp Neurol 65:327-335
63. Sima AA, Hinton D (1983) Hirano-bodies in the distal symmetric polyneuropathy of the spontaneously diabetic BB-Wistar rat. Acta Neurol Scand 68:107-112
64. Soriano Z, Pardee JD (2004) M34 Actin regulatory protein is a sensitive diagnostic marker for early- and late-stage mammary carcinomas. Clin Cancer Res 10:4437-4443
65. Tomonaga M (1974) Ultrastructure of Hirano bodies. Acta Neuropathol (Berl) 28:365-366
66. Tomonaga M (1983) Hirano body in extraocular muscle. Acta Neuropathol (Berl) 60:309-313
67. Yamamoto T, Hirano A (1985) Hirano bodies in the perikaryon of the Purkinje cell in a case of Alzheimer's disease. Acta Neuropathol (Berl) 67:167-169