메뉴 건너뛰기




Volumn 15, Issue 28, 2008, Pages 2991-2999

Metabolic-inflammatory changes, and accelerated atherosclerosis in HIV patients: Rationale for preventative measures

Author keywords

Atherosclerosis; Coronary heart disease; HIV; Hyperlipidaemia; Lipodystrophy; Macrophages; Statins

Indexed keywords

ALPHA TOCOPHEROL; AMPRENAVIR; ANTILIPEMIC AGENT; ANTIRETROVIRUS AGENT; C REACTIVE PROTEIN; CYTOKINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INDINAVIR; LIPID; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR;

EID: 58149384809     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986708786848668     Document Type: Review
Times cited : (25)

References (78)
  • 3
    • 34247476743 scopus 로고    scopus 로고
    • Cardiovascular risks of antiretroviral therapy
    • Stein, J.H. Cardiovascular risks of antiretroviral therapy. N. Engl. J. Med., 2007, 356, 1773-5.
    • (2007) N. Engl. J. Med , vol.356 , pp. 1773-1775
    • Stein, J.H.1
  • 4
    • 0038543135 scopus 로고    scopus 로고
    • Coronary heart disease in HIV-infected patients in the highly active antiretroviral treatment era
    • Vittecoq, D.; Escaut, L.; Chironi, G.; Teicher, E.; Monsuez, J.J.; Andrejak, M.; Simon, A. Coronary heart disease in HIV-infected patients in the highly active antiretroviral treatment era. AIDS, 2003, 17 (Suppl 1), S70-6.
    • (2003) AIDS , vol.17 , Issue.SUPPL. 1
    • Vittecoq, D.1    Escaut, L.2    Chironi, G.3    Teicher, E.4    Monsuez, J.J.5    Andrejak, M.6    Simon, A.7
  • 5
    • 33645467423 scopus 로고    scopus 로고
    • Law, M.G.; Friis-Moller, N.; El-Sadr, W.M.; Weber, R.; Reiss, P.; D'Arminio Monforte, A.; Thiebaut, R.; Morfeldt, L.; De Wit, S.; Pradier, C.; Calvo, G.; Kirk, O.; Sabin, C.A.; Phillips, A.N.; Lundgren, J.D. the use of the Framingham equation to predict myocardial infarctions in HIV-infected patients: Comparison with observed events in the D:A:D Study. HIV Med., 2006, 7, 218-30.
    • Law, M.G.; Friis-Moller, N.; El-Sadr, W.M.; Weber, R.; Reiss, P.; D'Arminio Monforte, A.; Thiebaut, R.; Morfeldt, L.; De Wit, S.; Pradier, C.; Calvo, G.; Kirk, O.; Sabin, C.A.; Phillips, A.N.; Lundgren, J.D. the use of the Framingham equation to predict myocardial infarctions in HIV-infected patients: Comparison with observed events in the D:A:D Study. HIV Med., 2006, 7, 218-30.
  • 10
    • 0043128571 scopus 로고    scopus 로고
    • An objective lipodystrophy severity grading scale derived from the lipodystrophy case definition score
    • Carr, A.; Law, M. An objective lipodystrophy severity grading scale derived from the lipodystrophy case definition score. J. Acquir. Immune. Defic. Syndr., 2003, 33, 571-6.
    • (2003) J. Acquir. Immune. Defic. Syndr , vol.33 , pp. 571-576
    • Carr, A.1    Law, M.2
  • 13
    • 34447532409 scopus 로고    scopus 로고
    • Visceral fat as target of highly active antiretroviral therapy-associated metabolic syndrome
    • Barbaro, G. Visceral fat as target of highly active antiretroviral therapy-associated metabolic syndrome. Curr. Pharm. Des., 2007, 13, 2208-13.
    • (2007) Curr. Pharm. Des , vol.13 , pp. 2208-2213
    • Barbaro, G.1
  • 18
    • 0347985272 scopus 로고    scopus 로고
    • Obesity-induced inflammatory changes in adipose tissue
    • Wellen, K.E.; Hotamisligil, G.S. Obesity-induced inflammatory changes in adipose tissue. J. Clin. Invest., 2003, 112, 1785-8.
    • (2003) J. Clin. Invest , vol.112 , pp. 1785-1788
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 19
    • 0038577223 scopus 로고    scopus 로고
    • Minireview: Adiposity, inflammation, and atherogenesis
    • Lyon, C.J.; Law, R.E.; Hsueh, W.A. Minireview: Adiposity, inflammation, and atherogenesis. Endocrinology, 2003, 144, 2195-200.
    • (2003) Endocrinology , vol.144 , pp. 2195-2200
    • Lyon, C.J.1    Law, R.E.2    Hsueh, W.A.3
  • 21
    • 17144380822 scopus 로고    scopus 로고
    • The metabolic syndrome
    • Eckel, R.H.; Grundy, S.M.; Zimmet, P.Z. The metabolic syndrome. Lancet, 2005, 365, (9468), 1415-28.
    • (2005) Lancet , vol.365 , Issue.9468 , pp. 1415-1428
    • Eckel, R.H.1    Grundy, S.M.2    Zimmet, P.Z.3
  • 22
    • 26244448904 scopus 로고    scopus 로고
    • A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: Role of free fatty acids and tumor necrosis factor alpha
    • Suganami, T.; Nishida, J.; Ogawa, Y. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: Role of free fatty acids and tumor necrosis factor alpha. Arterioscler. Thromb. Vasc. Biol., 2005, 25, 2062-8.
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 2062-2068
    • Suganami, T.1    Nishida, J.2    Ogawa, Y.3
  • 23
    • 0026716993 scopus 로고
    • Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunedeficiency syndrome
    • Grunfeld, C.; Pang, M.; Doerrler, W.; Shigenaga, J.K.; Jensen, P.; Feingold, K.R. Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunedeficiency syndrome. J. Clin. Endocrinol. Metab., 1992, 74, 1045-52.
    • (1992) J. Clin. Endocrinol. Metab , vol.74 , pp. 1045-1052
    • Grunfeld, C.1    Pang, M.2    Doerrler, W.3    Shigenaga, J.K.4    Jensen, P.5    Feingold, K.R.6
  • 27
    • 0034631873 scopus 로고    scopus 로고
    • Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: A 5-year cohort study
    • Tsiodras, S.; Mantzoros, C.; Hammer, S.; Samore, M. Effects of protease inhibitors on hyperglycemia, hyperlipidemia, and lipodystrophy: A 5-year cohort study. Arch. Intern. Med., 2000, 160, 2050-6.
    • (2000) Arch. Intern. Med , vol.160 , pp. 2050-2056
    • Tsiodras, S.1    Mantzoros, C.2    Hammer, S.3    Samore, M.4
  • 29
    • 0035661381 scopus 로고    scopus 로고
    • HIV protease inhibitors project apolipoprotein B from degradation by the proteosome: A potential mechanism for protease inhibitor-induced hyperlipidemia
    • Liang, J.S.; Distler, O.; Cooper, D.A.; Jamil, H.; Deckelbaum, R.J.; Ginsberg, H.N.; Sturley, S.L. HIV protease inhibitors project apolipoprotein B from degradation by the proteosome: A potential mechanism for protease inhibitor-induced hyperlipidemia. Nat. Med., 2001, 7, 1327-31.
    • (2001) Nat. Med , vol.7 , pp. 1327-1331
    • Liang, J.S.1    Distler, O.2    Cooper, D.A.3    Jamil, H.4    Deckelbaum, R.J.5    Ginsberg, H.N.6    Sturley, S.L.7
  • 31
    • 0037083729 scopus 로고    scopus 로고
    • CD36 deficiency induced by antiretroviral therapy
    • Serghides, L.; Nathoo, S.; Walmsley, S.; Kain, K.C. CD36 deficiency induced by antiretroviral therapy. AIDS, 2002, 16, 353-8.
    • (2002) AIDS , vol.16 , pp. 353-358
    • Serghides, L.1    Nathoo, S.2    Walmsley, S.3    Kain, K.C.4
  • 33
    • 15244357264 scopus 로고    scopus 로고
    • HIV protease inhibitors-induced atherosclerosis: Prevention by alpha-tocopherol
    • Munteanu, A.; Ricciarelli, R.; Zingg, J.M. HIV protease inhibitors-induced atherosclerosis: Prevention by alpha-tocopherol. IUBMB Life, 2004, 56, 629-31.
    • (2004) IUBMB Life , vol.56 , pp. 629-631
    • Munteanu, A.1    Ricciarelli, R.2    Zingg, J.M.3
  • 34
    • 15244358438 scopus 로고    scopus 로고
    • CD36 overexpression in ritonavir-treated THP-1 cells is reversed by alphatocopherol
    • Munteanu, A.; Zingg, J.M.; Ricciarelli, R.; Azzi, A. CD36 overexpression in ritonavir-treated THP-1 cells is reversed by alphatocopherol. Free Radic. Biol. Med., 2005, 38, 1047-56.
    • (2005) Free Radic. Biol. Med , vol.38 , pp. 1047-1056
    • Munteanu, A.1    Zingg, J.M.2    Ricciarelli, R.3    Azzi, A.4
  • 37
    • 20544442521 scopus 로고    scopus 로고
    • Increased CD36 expression in vertically human immunodeficiency virus-infected children unrelated to antiretroviral therapy
    • Meroni, L.; Giacomet, V.; Morelli, P.; Erba, P.; Galazzi, M.; Riva, A.; Vigano, A.; Galli, M. Increased CD36 expression in vertically human immunodeficiency virus-infected children unrelated to antiretroviral therapy. Pediatr. Infect. Dis. J., 2005, 24, 576-7.
    • (2005) Pediatr. Infect. Dis. J , vol.24 , pp. 576-577
    • Meroni, L.1    Giacomet, V.2    Morelli, P.3    Erba, P.4    Galazzi, M.5    Riva, A.6    Vigano, A.7    Galli, M.8
  • 39
    • 1642545106 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis: Role of C-reactive protein in risk assessment
    • Libby, P.; Ridker, P.M. Inflammation and atherosclerosis: Role of C-reactive protein in risk assessment. Am. J. Med., 2004, 116 (Suppl 6A), 9S-16S.
    • (2004) Am. J. Med , vol.116 , Issue.SUPPL. 6A
    • Libby, P.1    Ridker, P.M.2
  • 40
    • 0035799331 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein: Potential adjunct for global risk assessment in the primary prevention of cardiovascular disease
    • Ridker, P.M. High-sensitivity C-reactive protein: Potential adjunct for global risk assessment in the primary prevention of cardiovascular disease. Circulation, 2001, 103, 1813-8.
    • (2001) Circulation , vol.103 , pp. 1813-1818
    • Ridker, P.M.1
  • 41
    • 33845988732 scopus 로고    scopus 로고
    • The role of C-reactive protein activation of nuclear factor kappa-B in the pathogenesis of unstable angina
    • Jialal, I.; Devaraj, S. The role of C-reactive protein activation of nuclear factor kappa-B in the pathogenesis of unstable angina. J. Am. Coll. Cardiol., 2007, 49, 195-7.
    • (2007) J. Am. Coll. Cardiol , vol.49 , pp. 195-197
    • Jialal, I.1    Devaraj, S.2
  • 42
    • 20944433273 scopus 로고    scopus 로고
    • Clinical value of C-reactive protein measurements in HIV-positive patients
    • Noursadeghi, M.; Miller, R.F. Clinical value of C-reactive protein measurements in HIV-positive patients. Int. J. STD AIDS, 2005, 16, 438-41.
    • (2005) Int. J. STD AIDS , vol.16 , pp. 438-441
    • Noursadeghi, M.1    Miller, R.F.2
  • 45
    • 0038701685 scopus 로고    scopus 로고
    • T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy
    • Hunt, P.W.; Martin, J.N.; Sinclair, E.; Bredt, B.; Hagos, E.; Lampiris, H.; Deeks, S.G. T cell activation is associated with lower CD4+ T cell gains in human immunodeficiency virus-infected patients with sustained viral suppression during antiretroviral therapy. J. Infect. Dis., 2003, 187, 1534-43.
    • (2003) J. Infect. Dis , vol.187 , pp. 1534-1543
    • Hunt, P.W.1    Martin, J.N.2    Sinclair, E.3    Bredt, B.4    Hagos, E.5    Lampiris, H.6    Deeks, S.G.7
  • 46
    • 0343920019 scopus 로고    scopus 로고
    • T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: A longitudinal analysis in patients before and during highly active retroviral therapy (HAART)
    • Hazenberg, M.D.; Stuart, J.W.; Otto, S.A.; Borleffs, J.C.; Boucher, C.A.; de Boer, R.J.; Miedema, F.; Hamann, D. T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: A longitudinal analysis in patients before and during highly active retroviral therapy (HAART). Blood, 2000, 95, (1), 249-55.
    • (2000) Blood , vol.95 , Issue.1 , pp. 249-255
    • Hazenberg, M.D.1    Stuart, J.W.2    Otto, S.A.3    Borleffs, J.C.4    Boucher, C.A.5    de Boer, R.J.6    Miedema, F.7    Hamann, D.8
  • 48
    • 0023730723 scopus 로고
    • Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques
    • Hansson, G.K.; Jonasson, L.; Lojsthed, B.; Stemme, S.; Kocher, O.; Gabbiani, G. Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaques. Atherosclerosis, 1988, 72, 135-41.
    • (1988) Atherosclerosis , vol.72 , pp. 135-141
    • Hansson, G.K.1    Jonasson, L.2    Lojsthed, B.3    Stemme, S.4    Kocher, O.5    Gabbiani, G.6
  • 49
    • 0034642328 scopus 로고    scopus 로고
    • Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice
    • Zhou, X.; Nicoletti, A.; Elhage, R.; Hansson, G.K. Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice. Circulation, 2000, 102, 2919-22
    • (2000) Circulation , vol.102 , pp. 2919-2922
    • Zhou, X.1    Nicoletti, A.2    Elhage, R.3    Hansson, G.K.4
  • 50
    • 0033048632 scopus 로고    scopus 로고
    • Cytokine expression in advanced human atherosclerotic plaques: Dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines
    • Frostegard, J.; Ulfgren, A.K.; Nyberg, P.; Hedin, U.; Swedenborg, J.; Andersson, U.; Hansson, G.K. Cytokine expression in advanced human atherosclerotic plaques: Dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis, 1999, 145, 33-43.
    • (1999) Atherosclerosis , vol.145 , pp. 33-43
    • Frostegard, J.1    Ulfgren, A.K.2    Nyberg, P.3    Hedin, U.4    Swedenborg, J.5    Andersson, U.6    Hansson, G.K.7
  • 51
    • 0037840375 scopus 로고    scopus 로고
    • HIV-1 Tat protein and endothelium: From protein/ cell interaction to AIDS-associated pathologies
    • Rusnati, M.; Presta, M. HIV-1 Tat protein and endothelium: From protein/ cell interaction to AIDS-associated pathologies. Angiogenesis, 2002, 5, 141-51.
    • (2002) Angiogenesis , vol.5 , pp. 141-151
    • Rusnati, M.1    Presta, M.2
  • 52
    • 0141835815 scopus 로고    scopus 로고
    • Paladugu, R.; Fu, W.; Conklin, B.S.; Lin, P.H.; Lumsden, A.B.; Yao, Q.; Chen, C. HIV Tat protein causes endothelial dysfunction in porcine coronary arteries. J. Vasc. Surg., 2003, 38, 549-6.
    • Paladugu, R.; Fu, W.; Conklin, B.S.; Lin, P.H.; Lumsden, A.B.; Yao, Q.; Chen, C. HIV Tat protein causes endothelial dysfunction in porcine coronary arteries. J. Vasc. Surg., 2003, 38, 549-6.
  • 53
    • 1842455359 scopus 로고    scopus 로고
    • Shed membrane proteins from T lymphocytes impair endothelial function and regulate endothelial protein expression
    • Martin, S.; Tesse, A.; Hugel, B.; Martinez, M.C.; Morel, O.; Freyssinet, J.M.; Andriantsitohaina, R. Shed membrane proteins from T lymphocytes impair endothelial function and regulate endothelial protein expression. Circulation, 2004, 109, 1653-9.
    • (2004) Circulation , vol.109 , pp. 1653-1659
    • Martin, S.1    Tesse, A.2    Hugel, B.3    Martinez, M.C.4    Morel, O.5    Freyssinet, J.M.6    Andriantsitohaina, R.7
  • 54
    • 9144251760 scopus 로고    scopus 로고
    • Expanding role of circulating adhesion molecules in assessing prognosis and treatment response in human immunodeficiency virus infection
    • Sipsas, N.V.; Sfikakis, P.P. Expanding role of circulating adhesion molecules in assessing prognosis and treatment response in human immunodeficiency virus infection. Clin. Diagn. Lab. Immunol., 2004, 11, 996-1001.
    • (2004) Clin. Diagn. Lab. Immunol , vol.11 , pp. 996-1001
    • Sipsas, N.V.1    Sfikakis, P.P.2
  • 55
    • 0032501991 scopus 로고    scopus 로고
    • Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease
    • Ridker, P.M.; Cushman, M.; Stampfer, M.J.; Tracy, R.P.; Hennekens, C.H. Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease. Circulation, 1998, 97, 425-8.
    • (1998) Circulation , vol.97 , pp. 425-428
    • Ridker, P.M.1    Cushman, M.2    Stampfer, M.J.3    Tracy, R.P.4    Hennekens, C.H.5
  • 56
  • 57
    • 0032501738 scopus 로고    scopus 로고
    • Plasma concentration of soluble intercellular adhesion module 1 and risks of future myocardial infarction in apparently healthy men
    • Ridker, P.M.; Hennekens, C.H.; Roitman-Johnson, B.; Stampfer, M.J.; Allen, J. Plasma concentration of soluble intercellular adhesion module 1 and risks of future myocardial infarction in apparently healthy men. Lancet, 1998, 351, 88-92.
    • (1998) Lancet , vol.351 , pp. 88-92
    • Ridker, P.M.1    Hennekens, C.H.2    Roitman-Johnson, B.3    Stampfer, M.J.4    Allen, J.5
  • 59
    • 31844451010 scopus 로고    scopus 로고
    • Anti-inflammatory effects of statins: Clinical evidence and basic mechanisms
    • Jain, M.K.; Ridker, P.M. Anti-inflammatory effects of statins: Clinical evidence and basic mechanisms. Nat. Rev. Drug Discov., 2005, 4, 977-87.
    • (2005) Nat. Rev. Drug Discov , vol.4 , pp. 977-987
    • Jain, M.K.1    Ridker, P.M.2
  • 61
    • 2942670689 scopus 로고    scopus 로고
    • Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?
    • Ridker, P.M.; Wilson, P.W.; Grundy, S.M. Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation, 2004, 109, 2818-25.
    • (2004) Circulation , vol.109 , pp. 2818-2825
    • Ridker, P.M.1    Wilson, P.W.2    Grundy, S.M.3
  • 62
    • 29644444564 scopus 로고    scopus 로고
    • Effects of statins on endothelial function and lipid profile in HIV infected persons receiving protease-inhibitor containing anti-retroviral therapy: A randomised double blind crossover trial
    • Hurlimann, D.; Chenevard, R.; Ruschitzka, F.; Flepp, M.; Enseleit, F.; Bechir, M.; Kobza, R.; Muntwyler, J.; Ledergerber, B.; Luscher, T.F.; Noll, G.; Weber, R. Effects of statins on endothelial function and lipid profile in HIV infected persons receiving protease-inhibitor containing anti-retroviral therapy: A randomised double blind crossover trial. Heart, 2006, 92, (1), 110-2.
    • (2006) Heart , vol.92 , Issue.1 , pp. 110-112
    • Hurlimann, D.1    Chenevard, R.2    Ruschitzka, F.3    Flepp, M.4    Enseleit, F.5    Bechir, M.6    Kobza, R.7    Muntwyler, J.8    Ledergerber, B.9    Luscher, T.F.10    Noll, G.11    Weber, R.12
  • 64
    • 0030058148 scopus 로고    scopus 로고
    • Inhibition of the mevalonate pathway: Benefits beyond cholesterol reduction?
    • Massy, Z.A.; Keane, W.F.; Kasiske, B.L. Inhibition of the mevalonate pathway: Benefits beyond cholesterol reduction? Lancet, 1996, 347, 102-3.
    • (1996) Lancet , vol.347 , pp. 102-103
    • Massy, Z.A.1    Keane, W.F.2    Kasiske, B.L.3
  • 65
    • 0036790614 scopus 로고    scopus 로고
    • Statin therapy in acute coronary syndromes: Mechanistic insight into clinical benefit
    • Sposito, A.C.; Chapman, M.J. Statin therapy in acute coronary syndromes: mechanistic insight into clinical benefit. Arterioscler. Thromb. Vasc. Biol., 2002, 22, 1524-34.
    • (2002) Arterioscler. Thromb. Vasc. Biol , vol.22 , pp. 1524-1534
    • Sposito, A.C.1    Chapman, M.J.2
  • 66
    • 0036322869 scopus 로고    scopus 로고
    • Isoprenoids as mediators of the biological effects of statins
    • Liao, J.K. Isoprenoids as mediators of the biological effects of statins. J. Clin. Invest., 2002, 110, 285-8.
    • (2002) J. Clin. Invest , vol.110 , pp. 285-288
    • Liao, J.K.1
  • 67
    • 33747243397 scopus 로고    scopus 로고
    • Statin therapy for native and periinterventional coronary heart disease
    • Smith, D.A.; Galin, I. Statin therapy for native and periinterventional coronary heart disease. Curr. Mol. Med., 2006, 6, 589-602.
    • (2006) Curr. Mol. Med , vol.6 , pp. 589-602
    • Smith, D.A.1    Galin, I.2
  • 68
    • 4444376712 scopus 로고    scopus 로고
    • Signalling to NFkappa-B
    • Hayden, M.S.; Ghosh, S. Signalling to NFkappa-B. Genes Dev., 2004, 18, 2195-224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 69
    • 0034978984 scopus 로고    scopus 로고
    • Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation
    • Wong, B.; Lumma, W.C.; Smith, A.M.; Sisko, J.T.; Wright, S.D.; Cai, T.Q. Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation. J. Leukoc. Biol., 2001, 69, 959-62.
    • (2001) J. Leukoc. Biol , vol.69 , pp. 959-962
    • Wong, B.1    Lumma, W.C.2    Smith, A.M.3    Sisko, J.T.4    Wright, S.D.5    Cai, T.Q.6
  • 70
    • 4644265227 scopus 로고    scopus 로고
    • An emerging role for Krüppel-like factors in vascular biology
    • Feinberg, M.W.; Lin, Z.; Fisch, S.; Jain, M.K. An emerging role for Krüppel-like factors in vascular biology. Trends Cardiovasc. Med., 2004, 14, 241-6.
    • (2004) Trends Cardiovasc. Med , vol.14 , pp. 241-246
    • Feinberg, M.W.1    Lin, Z.2    Fisch, S.3    Jain, M.K.4
  • 71
    • 0242468526 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors as therapeutic targets in inflammation
    • Plutzky, J. Peroxisome proliferator-activated receptors as therapeutic targets in inflammation. J. Am. Coll. Cardiol., 2003, 42, 1764-6.
    • (2003) J. Am. Coll. Cardiol , vol.42 , pp. 1764-1766
    • Plutzky, J.1
  • 75
    • 8544237037 scopus 로고    scopus 로고
    • Statin induction of liver fatty acid-binding protein (L-FABP) gene expression is peroxisome-activated receptor-alpha-dependent
    • Landrier, J.F.; Thomas, C.; Grober, J.; Duez, H.; Percevault, F.; Souidi, M.; Linard, C.; Staels, B.; Besnard, P. Statin induction of liver fatty acid-binding protein (L-FABP) gene expression is peroxisome-activated receptor-alpha-dependent. J. Biol. Chem., 2004, 279, 45512-8.
    • (2004) J. Biol. Chem , vol.279 , pp. 45512-45518
    • Landrier, J.F.1    Thomas, C.2    Grober, J.3    Duez, H.4    Percevault, F.5    Souidi, M.6    Linard, C.7    Staels, B.8    Besnard, P.9
  • 76
    • 0036445650 scopus 로고    scopus 로고
    • Modulation of inflammatory mediators and PPARgamma and NFkappaB expression by pravastin in response to lipoproteins in human monocytes in vitro
    • Zelvyte, I.; Dominaitiene, R.; Crisby, M.; Janciauskiene, S. Modulation of inflammatory mediators and PPARgamma and NFkappaB expression by pravastin in response to lipoproteins in human monocytes in vitro. Pharmacol. Res., 2002, 45, 147-54.
    • (2002) Pharmacol. Res , vol.45 , pp. 147-154
    • Zelvyte, I.1    Dominaitiene, R.2    Crisby, M.3    Janciauskiene, S.4
  • 77
    • 33846025430 scopus 로고    scopus 로고
    • Liuzzo, G.; Santamaria, M.; Biasucci, L.M.; Narducci, M.; Colafrancesco, V.; Porto, A.; Brugaletta, S.; Pinnelli, M.; Rizzello, V.; Maseri, A.; Crea, F. Persistent activation of nuclear factor kappa-B signalling pathway in patients with unstable angina and elevated levels of C-reactive protein evidence for a direct proinflammatory effect of azide and lipopoylsaccharide-free C-reactive protein on human monocytes via nuclear factor kappa-B activation. J. Am. Coll. Cardiol., 2007, 49, 185-94.
    • Liuzzo, G.; Santamaria, M.; Biasucci, L.M.; Narducci, M.; Colafrancesco, V.; Porto, A.; Brugaletta, S.; Pinnelli, M.; Rizzello, V.; Maseri, A.; Crea, F. Persistent activation of nuclear factor kappa-B signalling pathway in patients with unstable angina and elevated levels of C-reactive protein evidence for a direct proinflammatory effect of azide and lipopoylsaccharide-free C-reactive protein on human monocytes via nuclear factor kappa-B activation. J. Am. Coll. Cardiol., 2007, 49, 185-94.
  • 78
    • 0035843962 scopus 로고    scopus 로고
    • Structural mechanism for statin inhibition of HMG-CoA reductase
    • Istvan, E. S.; Deisendorf, J. Structural mechanism for statin inhibition of HMG-CoA reductase. Science, 2001, 292, 1160-4
    • (2001) Science , vol.292 , pp. 1160-1164
    • Istvan, E.S.1    Deisendorf, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.