A mutation in CFTR modifies the effects of the adenylate kinase inhibitor Ap5A on channel gating

Biophysical Journal

Volumn 95, Issue 11, 2008, Pages 5178-5185

  Dong, Qian ^a   Randak, Christoph O ^a   Welsh, Michael J ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; DINUCLEOSIDE PHOSPHATE; ENZYME INHIBITOR; P(1),P(5) DI(ADENOSINE 5' )PENTAPHOSPHATE; P(1),P(5)-DI(ADENOSINE-5'-)PENTAPHOSPHATE; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHANNEL GATING; CHEMISTRY; CYTOSOL; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HELA CELL; HUMAN; METABOLISM; POINT MUTATION; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE;

5'-NUCLEOTIDASE; ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; BINDING SITES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOSOL; DINUCLEOSIDE PHOSPHATES; ENZYME INHIBITORS; HELA CELLS; HUMANS; ION CHANNEL GATING; POINT MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY;

EID: 58149360314     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1529/biophysj.108.140897     Document Type: Article

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