Farnesyltransferase inhibitors target multiple endothelial cell functions in angiogenesis

Angiogenesis

Volumn 11, Issue 4, 2008, Pages 337-346

  Scott, Alice N ^a   Hetheridge, Clare ^a   Reynolds, Andrew R ^b   Nayak, Vrinda ^a   Hodivala Dilke, Kairbaan ^b   Mellor, Harry ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Angiogenesis; Cell migration; Endothelial cell; Farnesyltransferase inhibitor; VEGF

Indexed keywords

2 [[2 [[2 [(2 AMINO 3 MERCAPTOPROPYL)AMINO] 3 METHYLPENTYL]OXY] 1 OXO 3 PHENYLPROPYL]AMINO] 4 (METHYLSULFONYL)BUTANOIC ACID ISOPROPYL ESTER; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE;

ANIMALS; AORTA; BIOLOGICAL ASSAY; CELL ADHESION; CELL PROLIFERATION; CELLS, CULTURED; CHEMOTAXIS; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; HUMANS; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

RATTUS;

EID: 58149340084     PISSN: 09696970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10456-008-9115-3     Document Type: Article

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