The expression and the functional roles of tissue factor and protease-activated receptor-2 on SW620 cells

Oncology Reports

Volumn 20, Issue 5, 2008, Pages 1069-1076

  Zhou, Hong ^a   Hu, Hongxin ^a   Shi, Wenxia ^a   Ling, Shucai ^b   Wang, Ting ^a   Wang, Haibo ^a  

^a JIANGSU UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Colonic cancer cells; Migration; Protease activated receptors; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR 7A; INTERLEUKIN 8; MESSENGER RNA; PROTEIN ANTIBODY; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; THROMBOPLASTIN; TUMOR ANTIGEN;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CELL FUNCTION; CELL MEMBRANE; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CELLULAR DISTRIBUTION; COLON CANCER; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; METASTASIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; CELL MOTION; COLON TUMOR; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COLONIC NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-8; NEOPLASM INVASIVENESS; RECEPTOR, PAR-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THROMBOPLASTIN;

EID: 58149330721     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000111     Document Type: Article

References (35)

1. Fidler IJ: Critical factors in the biology of human cancer metastasis: twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res 50: 6130-6138, 1990.
2. Rickles FR, Patierno S and Fernandez PM: Tissue factor, thrombin, and cancer. Chest 124: S58-S68, 2003.
3. Versteeg HH, Spek CA, Peppelenbosch MP and Richel DJ: Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathways. Mol Med 10: 1-6, 2004.
4. Callander NS, Varki N and Rao LV: Immuno-histochemical identification of tissue factor in solid tumors. Cancer 70: 1194-1201, 1992.
5. Mueller BM, Reisfeld RA, Edgington TS and Ruf W: Expression of tissue factor by melanoma cells promotes efficient hematogenous metastasis. Proc Natl Acad Sci USA 89: 11832-11836, 1992.
6. Kataoka H, Uchino H, Asada Y, et al: Analysis of tissue factor and tissue factor pathway inhibitor expression in human colorectal carcinoma cell lines and metastatic sublines to the liver. Int J Cancer 72: 878-884, 1997.
7. Bromberg ME, Konigsberg WH, Madison JF, Pawashet A and Garen A: Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation. Proc Natl Acad Sci USA 92: 8205-8209, 1995.
8. Kakkar AK, Chinswangwatanakul V, Lemoine NR, Tebbutt S and Williamson RC: Role of tissue factor expression on tumour cell invasion and growth of experimental pancreatic adenocarcinoma. Br J Surg 86: 890-894, 1999.
9. Schmidlin F and Bunnett NW: Protease-activated receptors: how proteases signal to cells. Curr Opin Pharmacol 1: 575-582, 2001.
10. Macfarlane SR, Seatter MJ, Kanke T, Hunter G and Plevin R: Proteinase activated receptors. Pharmacol Rev 53: 245-282, 2001.
11. Uehara A, Muramoto K, Takada H and Sugawara S: Neutrophil serine proteinases activate human nonepithelial cells to produce inflammatory cytokines through protease-activated receptor 2. J Immunol 170: 5690-5696, 2003.
12. Camerer E, Kataoka H, Kahn M, Lease K and Coughlin SR: Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells. J Biol Chem 277: 16081-16087, 2002.
13. Takeuchi T, Harris JL, Huang W, Yan KW, Coughlin SR and Craik CS: Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and singlechain urokinase-type plasminogen activator as substrates. J Biol Chem 275: 26333-26342, 2000.
14. Massi D, Naldini A, Ardinghi C, et al: Expression of protease-activated receptors 1 and 2 in melanocytic nevi and malignant melanoma. Hum Pathol 36: 676-685, 2005.
15. Ahamed J and Ruf W: Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain. J Biol Chem 279: 23038-23044, 2004.
16. Bromberg ME, Bailly MA and Konigsberg WH: Role of protease-activated receptor 1 in tumor metastasis promoted by tissue factor. Thromb Haemost 86: 1210-1214, 2001.
17. Xie K: Interleukin-8 and human cancer biology. Cytokine Growth Factor Rev 12: 375-391, 2001.
18. Hijortoe GM, Petersen LC, Albrektsen T, et al: Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDAMB-231 cells is mediated by PAR-2 and results in increased cell migration. Blood 103: 3029-3037, 2004.
19. Mackman N: Role of tissue factor in hemostasis, thrombosis, and vascular development. Arterioscler Thromb Vasc Biol 24: 1015-1022, 2004.
20. Hembrough TA, Swartz GM, Papathanassiu A, et al: Tissue factor/ factor VIIa inhibitors block angiogenesis and tumor growth through a nonhemostatic mechanism. Cancer Res 63: 2997-3000, 2003.
21. Poon RTP, Lau CPY, Ho JWY, Yue WC, Fan ST and Wong J: Tissue factor expression correlates with tumor angiogenesis and invasiveness in Human hepatocellular carcinoma. Clin Cancer Res 9: 5339-5345, 2003.
22. Yu JL, May L, Lhotak V, et al: Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis. Blood 105: 1734-1741, 2005.
23. Nitori N, Ino Y, Nakanishi Y, et al: Prognostic significance of tissue factor in pancreatic ductal adenocarcinoma. Clin Cancer Res 11: 2531-2539, 2005.
24. Kaido T, Oe H, Yoshikawa A, Mori A, Arii S and Imamura M: Tissue factor is a useful prognostic factor of recurrence in hepatocellular carcinoma in 5-year survivors. Hepatogastroenterology 52: 1383-1387, 2005.
25. Shi X, Gangadharan B, Brass LF, Ruf W and Mueller BM: Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis. Mol Cancer Res 2: 395-402, 2004.
26. Yin YJ, Salah Z, Granovsky SG, et al: Human proteaseactivated receptor 1 expression in malignant epithelia: a role in invasiveness. Arterioscler Thromb Vasc Biol 23: 940-944, 2003.
27. Ge L, Shenoy SK, Lefkowitz RJ and Fea KD: Constitutive protease-activated receptor-2-mediated migration of MDA MB- 231 breast cancer cells requires both -Arrestin-1 and -2. J Biol Chem 279: 55419-55424, 2004.
28. Darmoul D, Gratio V, Devaud H, Lehy T and Laburthe M: Aberrant expression and activation of the thrombin receptor protease-activated receptor-1 induces cell proliferation and motility in human colon cancer cells. Am J Pathol 162: 1503-1513, 2003.
29. Arora P, Ricks TK and Trejo J: Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer. J Cell Sci 120: 921-928, 2007.
30. Morris DR, Ding Y, Ricks TK, Gullapalli A, Wolfe BL and Trejo J: Protease-activated receptor-2 is essential for factor VIIa and Xa-induced signaling, migration, and invasion of breast cancer cells. Cancer Res 66: 307-314, 2006.
31. Jiang X, Bailly MA, Panetti TS, Cappello M, Konigsberg WH and Bromberg ME: Formation of tissue factor-factor VIIafactor Xa complex promotes cellular signaling and migration of human breast cancer cells. J Thromb Haemost 2: 93-101, 2004.
32. Ahamed J, Versteeg HV, Kerver M, et al: Disulfide isomerization switches tissue factor from coagulation to cell signaling. Proc Natl Acad Sci USA 103: 13932-13937, 2006.
33. Camerer E and Trejo J: Cryptic messages: is noncoagulant tissue factor reserved for cell signaling. Proc Natl Acad Sci USA 103: 14259-14260, 2006.
34. Awasthi V, Mandal SK, Papanna V, Vijaya L, Rao M and Usha R: Modulation of tissue factor-factor VIIa signaling by lipid rafts and caveolae. Arterioscler Thromb Vasc Biol 27: 1447-1455, 2007.
35. Kubo F, Ueno S, Hiwatashi K, et al: Interleukin 8 in human hepatocellular carcinoma correlates with cancer cell invasion of vessels but not with tumor angiogenesis. Ann Surg Oncol 12: 800-807, 2005.