The heterotrimeric G-protein α-subunit Gαq regulates TCR-mediated immune responses through an Lck-dependent pathway

European Journal of Immunology

Volumn 38, Issue 11, 2008, Pages 3208-3218

  Ngai, Jacob ^a   Methi, Trond ^a   Andressen, Kjetil Wessel ^a   Levy, Finn Olav ^a   Torgersen, Knut Martin ^a   Vang, Torkel ^a   Wettschureck, Nina ^b   Taskén, Kjetil ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Signal transduction; T cells; TCR; Transgenic knockout mice

Indexed keywords

CD3 ANTIGEN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT I2; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT Q; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT Q11; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT S; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 5; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; LYMPHOCYTE ANTIGEN RECEPTOR; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOREGULATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSCRIPTION INITIATION; BIOSYNTHESIS; LEUKEMIA CELL LINE; PHYSIOLOGY; T LYMPHOCYTE;

CYTOKINES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; JURKAT CELLS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); NFATC TRANSCRIPTION FACTORS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSCRIPTION FACTOR AP-1;

EID: 58149330288     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838195     Document Type: Article

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