The role of CD4-Lck in T-cell receptor antagonism: Evidence for negative signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 19, 1996, Pages 10360-10365

  Racioppi, Luigi ^a   Matarese, Giuseppe ^a   D'Oro, Ugo ^b   De Pascale, Mariateresa ^a   Masci, Anna Maria ^a   Fontana, Silvia ^c   Zappacosta, Serafino ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b NATIONAL CANCER INSTITUTE   (United States)

^c Ctro Endocrinol ed Oncol S   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; INOSITOL PHOSPHATE; LIGAND; OKT 4; PHOSPHATIDYLINOSITIDE; PHOSPHOTRANSFERASE; RECEPTOR BLOCKING AGENT; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; L CELL; MOUSE; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD4; CLONE CELLS; COLUMBIDAE; CYTOCHROME C GROUP; CYTOTOXICITY, IMMUNOLOGIC; INOSITOL PHOSPHATES; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, INBRED STRAINS; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; T-LYMPHOCYTES; TRANSFECTION; VARIATION (GENETICS);

ANIMALIA;

EID: 0029790767     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.19.10360     Document Type: Article

References (43)

1. Janeway, C. A., Jr., & Bottomly, K. (1994) Cell 76, 275-285.
2. Matis, L. A., Glimcher, L. H., Paul, W. E. & Schwartz, R. H. (1983) Proc. Natl. Acad. Sci. USA 80, 6019-6028.
3. Ashwell, J. D., Fox, F. G. & Schwartz, R. H. (1986) J. Immunol. 136, 757-766.
4. Mannie, M. D. (1991) J. Theor. Biol. 151, 169-192.
5. Evavold, B. D. & Allen, P. (1991) Science 252, 1308-1310.
6. De Magistris, M. T., Alexander, M., Coggeshall, J., Altman, A., Gaeta, F. C. A., Grey, H. M. & Sette, A. (1992) Cell 68, 625-634.
7. Racioppi, L., Ronchese, F., Matis, L. A. & Germain, R. N. (1993) J. Exp. Med. 177, 1047-1060.
8. Hogquist, K. A., Jameson, S. C., Heath, W. R., Howard, J., Bevan, M. J. & Carbone, F. R. (1994) Cell 76, 17-27.
9. Page D M., Alexander, J., Snoke, K., Appella, E., Sette, A., Hedrick, S. M. & Grey, H. M. (1994) Proc. Natl. Acad. Sci. USA 91, 4057-4061.
10. Sloan-Lancaster, J., Evavold, B. D. & Allen, P. (1993) Nature (London) 363, 156-159.
11. Windhagen, A., Scholz, H., Hollsberg, P., Fukaura, H., Sette, A. & Hafler, D. A. (1995) Immunity 2, 373-380.
12. Klenerman, P., Rowland-Jones, S., McAdam, S., Edwards, J., Daenke, S., Lalloo, D., Köppe, B., Rosenberg, W., Boyd, D., Edwards, A., Giangrande, P., Phillips, R. E. & McMichael, A. E. (1994) Nature (London) 369, 403-407.
13. Bertolelli, A., Sette, A., Chisari, F. V., Penna, A., Levrero, M., De Carli, M., Fiaccadori, F. & Ferrari, C. (1994) Nature (London) 369, 407-414.
14. Chan, A. C., Desai, D. M. & Weiss, A. (1994) Annu. Rev. Immunol. 12, 555-592.
15. Perlmutter, R. M., Levin, S. D., Appleby, M. W., Anderson, S. J. & Alberola-Ila, J. (1993) Immunology 11, 451-499.
16. Vaillette, A., Bookman, M. A., Horak, E. M., Samelson, L. E. & Bolen, J. B. (1989) Nature (London) 338, 257-259.
17. Glaichenhaus, N., Shastri, N., Littman, D. R. & Turner, J. M. (1991) Cell 64, 511-520.
18. Duplay, P., Thome, M., Hervé, F. & Acuto, O. (1994) J. Exp. Med. 179, 1163-1172.
19. Thome, M., Duplay, P., Guttinger, M. & Acuto, O. (1995) J. Exp. Med. 181, 1997-2006.
20. Sloan-Lancaster, J., Shaw, A. S., Rothbard, J. B. & Allen, P. M. (1994) Cell 79, 913-922.
21. Madrenas, J., Wange, R. L., Wang, J. L., Isakov, N., Samelson, L. E. & Germain, R. N. (1995) Science 267, 515-518.
22. Williams, N. G., Paradis, H., Agarwal, S., Chares, D. L., Pelech, S. L. & Roberts, T. M. (1993) Proc. Natl. Acad. Sci. USA 90, 5772-5776.
23. Desai, D. M., Newton, M. E., Kadlecek, T. & Weiss, A. (1990) Nature (London) 348, 66-69.
24. Sussman, J. J., Mercep, M., Saito, T., Germain, R. N., Bonvini, E. & Ashwell, J. D. (1988) Nature (London) 334, 625-628.
25. Pelech, S. L. & Sanghera, J. S. (1992) Science 257, 1355-1357.
26. Bing, S., Jacinto, E., Hibi, M., Kallunki, T., Karin, M. & Ben-Neriah, Y. (1994) Cell 77, 727-731.
27. Jameson, S. C, Hogquist, K. A. & Bevan, M. J. (1994) Nature (London) 369, 750-752.
28. Vignali, D. A. A. & Strominger, J. L. (1994) J. Exp. Med. 179, 1945-1956.
29. Mannie, M. D., Rosser, J. M. & White, G. A. (1995) J. Immunol. 154, 2642-2646.
30. Mustelin, T., Coggeshall, K. M. & Altman, A. (1989) Proc. Natl. Acad. Sci. USA 86, 6302-6306.
31. Furukawa, T., Itoh, M., Krueger, N. X., Streuli, M. & Saito, H. (1994) Proc. Natl. Acad. Sci USA 91, 10928-10929.
32. Mustelin, T., Williams, S., Tailor, P., Couture, C, Zenner, G., Burn, P., Ashwell, J. D. & Altman, A. (1995) Eur. J. Immunol. 25, 942-946.
33. Nel, A. E., Pollak, S., Landreth, G., Ledbetter, J. A., Hultin, L., Williams, K., Katz, R. & Akerley, B. (1990) J. Immunol. 145, 971-979.
34. Weber, J. R., Bell, G. M., Han, N. Y., Pawson, T. & Imboden, J. B. (1992) J. Exp. Med. 176, 373-379.
35. Li, W., Whaley, C. D., Mondino, A. & Mueller, D. L. (1996) Science 271, 1272-1276.
36. Fields, P. E., Gajewski, T. F. & Fitch, F. W. (1996) Science 271, 1276-1278.
37. Xu, H. & Littman, R. (1993) Cell 74, 633-643.
38. Janeway, C. A., Jr., Haque, S., Smith, L. A. & Saizawa, K. (1987) J. Mol. Cell. Immunol. 3, 121-127.
39. Janeway, C. A., Jr. (1986) J. Mol. Cell. Immunol. 2, 179-190.
40. Emmrich, F., Strittmatter, U. & Eichmann, K. (1986) Proc. Natl. Acad. Sci. USA 83, 8298-8301.
41. Ledbetter, J. A., June, C. H., Rabinovitch, P. S., Grossmann, A., Tsu, T. T. & Imboden, J. B. (1988) Eur. J. Immunol. 18, 525-532.
42. Haughn, L., Grattonn, S., Caron, L., Sekaly, R. P., Veilette, A. & Julius, M. H. (1992) Nature (London) 358, 328-331.
43. Banda, N. K., Bernier, J., Kurahara, D. K., Kurrle, R., Haigwood, N., Sekaly, R. & Finkel, T. H. (1992) J. Exp. Med. 176, 1099-1106.