Reduced Cbl phosphorylation and degradation of the ζ-chain of the T-cell receptor/CD3 complex in T cells with low Lck levels

European Journal of Immunology

Volumn 38, Issue 9, 2008, Pages 2557-2563

  Methi, Trond ^a   Berge, Torunn ^a   Torgersen, Knut Martin ^a   Taskén, Kjetil ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

Cbl; CD3; Lck; T cells; T cell receptors

Indexed keywords

CBL PROTEIN; CD3 ANTIGEN; PROTEIN KINASE LCK; SMALL INTERFERING RNA; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ZETA CHAIN; UNCLASSIFIED DRUG; ANTIGEN T CELL RECEPTOR, ZETA CHAIN; CBL PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT;

ARTICLE; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOSOME; HUMAN; HUMAN CELL; INTERNALIZATION; LYSOSOME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RECEPTOR BINDING; RNA INTERFERENCE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UBIQUITINATION; IMMUNOLOGY; LEUKEMIA CELL LINE; METABOLISM; PHOSPHORYLATION;

HUMANS; JURKAT CELLS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-CBL; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; TRANSCRIPTION FACTOR AP-1; UBIQUITINATION;

EID: 55249092772     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200737837     Document Type: Article

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