Amplified hormonal counterregulatory responses to hypoglycemia in rats after systemic delivery of a SUR-1-selective K + channel opener?

Diabetes

Volumn 57, Issue 12, 2008, Pages 3327-3334

  Fan, Xiaoning ^a   Ding, Yuyan ^a   Cheng, Haiying ^a   Gram, Dorte X ^b   Sherwin, Robert S ^a   McCrimmon, Rory J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; NN414; POTASSIUM CHANNEL STIMULATING AGENT; UNCLASSIFIED DRUG; 6 CHLORO 3 (1 METHYLCYCLOPROPYLAMINO) 4H THIENO[3,2 E][1,2,4]THIADIAZINE 1,1 DIOXIDE; ABC TRANSPORTER; DRUG RECEPTOR; FUSED HETEROCYCLIC RINGS; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; SULFONYLUREA RECEPTOR; SULFOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; GLUCOSE CLAMP TECHNIQUE; HORMONAL REGULATION; HYPOGLYCEMIA; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; GLUCOSE BLOOD LEVEL; HOMEOSTASIS; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BICYCLO COMPOUNDS, HETEROCYCLIC; BLOOD GLUCOSE; CYCLIC S-OXIDES; DIABETES MELLITUS, TYPE 1; EPINEPHRINE; HOMEOSTASIS; HYPOGLYCEMIA; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DRUG;

EID: 58149328555     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-0793     Document Type: Article

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