Novel glucosensor for hypoglycemic detection localized to the portal vein

Diabetes

Volumn 46, Issue 9, 1997, Pages 1521-1525

  Hevener, Andrea L ^a   Bergman, Richard N ^a   Donovan, Casey M ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; CATECHOLAMINE; GLUCOSE; INSULIN; NORADRENALIN;

ADRENERGIC SYSTEM; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CATECHOLAMINE BLOOD LEVEL; DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; GLUCOSE INFUSION; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN INFUSION; INSULIN TREATMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; RAT;

EID: 0030851022     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.9.1521     Document Type: Article

References (25)

1. The DCCT Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes mellitus. N Engl J Med 329:977-986, 1993
2. The DCCT Research Group: Epidemiology of severe hypoglycemia in the Diabetes Control and Complications Trial. Am J Med 90:450-459, 1991
3. Cryer PE, Binder C, Bolli GB, Cherrington AD, Gale EAM, Gerich JE, Sherwin RS: Hypoglycemia in IDDM: conference summary. Diabetes 38:1193-1199, 1989
4. Gerich JE, Campbell PE: Overview of counterregulation and its abnormalities in diabetes mellitus. Diabetes Metab Rev 4:93-111, 1988
5. Niijima A: Afferent impulse discharges from glucoreceptors in the liver of the guinea pig. Ann NY Acad Sci 157:690-700, 1969
6. Schmitt M: Influence of hepatic portal receptors on hypothalamic feeding and satiety centers. Am J Physiol 225:1089-1095, 1973
7. Niijima A: Glucose sensitive afferent nerve fibers in the liver and regulation of blood glucose. Brain Res Bull 5 (Suppl. 4):175-179, 1980
8. Niijima A: Visceral afferents and metabolic functions. Diabetologia 20:325-330, 1981
9. Shimazu T: Neuronal regulation of hepatic glucose metabolism in mammals. Diabetes Metab Rev 3:185-206, 1987
10. Donovan CM, Halter JB, Bergman RN: Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia Diabetes 40:155-158, 1991
11. Donovan CM, Hamilton-Wessler M, Halter JB, Bergman RN: Primacy of liver glucosensors in the sympathetic response to progressive hypoglycemia Proc Natl Acad Sci USA 91:2863-2867, 1994
12. Forssmann WG, Ito S: Hepatocyte innervation in primates. J Cell Biol 74:299-313, 1977
13. Carobi C, Della TG, Magni F: Differential distribution of vagal afferent neurons from the rat liver. Neurosci Lett 62:255-260, 1985
14. Barja F, Mathison R: Sensory innervation of the rat portal vein and the hepatic artery. J Auton Nerv Syst 10:117-125, 1984
15. Berthoud HR, Kressel M, Neuhuber WL: An anterograde tracing study of the vagal innervation of rat liver, portal vein and biliary system. Anat Embryol 186:186-431, 1992
16. Berthoud HR, Kressel M, Neuhuber WL: Vagal afferent innervation of rat abdominal paraganglia as revealed by anterograde Dil-tracing and confocal microscopy. Acta Anat 152:127-132, 1995
17. Ishise S, Pegram BL, Yammamoto J, Kitamura Y, Frolich ED: Reference sample microsphere method: cardiac output and blood flows in conscious rat. Am J Physiol 239:H443-H449, 1980
18. Yasuhito S, Wagner HN Jr: Measurement of the distribution of cardiac output in unanesthetized rats. J Appl Physiol 30:879-884, 1971
19. Pueler JD, Johnson GA: Simultaneous single isotope derivative radioenzymatic assay for plasma norepinephrine, epinephrine, and dopamine. Life Sciences 21:625-636, 1977
20. Herbert V, Law K, Gottlieb C, Bleicher S: Coated charcoal immunoassay of insulin. J Clin Endocrinol Metab 25:1375-1384, 1965
21. Reitman S, Frankel S: A colorimetric method for the determination of serum glutarnic oxalacetic and glutamic pyruvic transaminases. Am J Clin Pathol 28:56-63, 1957
22. Lautt WW: Afferent and efferent neural roles in liver function. Prog Neurobiol 21:323-348, 1983
23. Shimizu N, Oomura Y, Novin D, Grijalva CV, Cooper PH: Functional correlation between lateral hypothalamic glucose-sensitive neurons and hepatic portal glucose-sensitive units in rats. Brain Res 265:49-54, 1985
24. Niijima A: Glucose sensors in viscera and control of blood glucose level. News Physiol Sci 2:164-167, 1987
25. Hamilton-Wessler M, Bergman RN, Halter JB, Watanabe RM, Donovan CM: The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs. Diabetes 43:1052-1060, 1994