O-Fucosylation of an antibody light chain: Characterization of a modification occurring on an IgG1 molecule

Glycobiology

Volumn 19, Issue 2, 2009, Pages 144-152

  Valliere Douglass, John F ^a   Brady, Lowell J ^a   Farnsworth, Chris ^a   Pace, Danielle ^a   Balland, Alain ^a   Wallace, Alison ^a   Wang, Wesley ^a   Treuheit, Michael J ^a   Yan, Boxu ^a  

^a Department of Analytical and Formulation Sciences ^*  (United States)

Author keywords

Antibody; ETD mass spectrometry; Light chain; Monosaccharide analysis; O fucosylation

Indexed keywords

ANTHRANILIC ACID DERIVATIVE; EPIDERMAL GROWTH FACTOR; FUCOSE; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN LIGHT CHAIN; MONOSACCHARIDE; PEPTIDE DERIVATIVE; RECOMBINANT PROTEIN; REDUCING AGENT; SERINE; THROMBOSPONDIN 1;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CATION EXCHANGE; CHO CELL; CONSENSUS SEQUENCE; CONTROLLED STUDY; DISSOCIATION; ELECTRON TRANSPORT; FLUORESCENCE ANALYSIS; FUCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; ION EXCHANGE CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN ISOLATION; PROTEIN MODIFICATION; PROTEIN MOTIF; RESIDUE ANALYSIS;

ANIMALS; ANTIBODIES; CHO CELLS; CRICETINAE; CRICETULUS; FUCOSE; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN LIGHT CHAINS; MASS SPECTROMETRY; RECOMBINANT PROTEINS;

CRICETULUS GRISEUS; MAMMALIA;

EID: 58149327074     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwn116     Document Type: Article

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