Chemotactic Factors Associated with Eosinophilic Gastrointestinal Diseases

Immunology and Allergy Clinics of North America

Volumn 29, Issue 1, 2009, Pages 141-148

  Blanchard, Carine ^a   Rothenberg, Marc E ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Chemokine; Cytokine; Eosinophil; Gastrointestinal; Pathogenesis

Indexed keywords

CELL ADHESION MOLECULE; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOTACTIC FACTOR; CYTOKINE; EOTAXIN; EOTAXIN 2; EOTAXIN 3; INTEGRIN;

CELL INFILTRATION; CELLULAR DISTRIBUTION; EOSINOPHIL; EOSINOPHILIC COLITIS; EOSINOPHILIC ESOPHAGITIS; EOSINOPHILIC GASTRITIS; EOSINOPHILIC GASTROENTERITIS; EOSINOPHILIC GASTROINTESTINAL DISORDER; GASTROINTESTINAL TRACT; HUMAN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVIEW; TH2 CELL;

ANIMALS; CELL ADHESION; CELL ADHESION MOLECULES; CELL MOVEMENT; CHEMOKINES; DISEASE MODELS, ANIMAL; EOSINOPHILIA; EOSINOPHILS; GASTROINTESTINAL DISEASES; HUMANS; IMMUNOTHERAPY; MICE; RECEPTORS, CHEMOKINE; TH2 CELLS;

EID: 58149269478     PISSN: 08898561     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.iac.2008.10.002     Document Type: Review

References (46)

1. Kato M., Kephart G.M., Talley N.J., et al. Eosinophil infiltration and degranulation in normal human tissue. Anat Rec 252 (1998) 418-425
2. DeBrosse C.W., Case J.W., Putnam P.E., et al. Quantity and distribution of eosinophils in the gastrointestinal tract of children. Pediatr Dev Pathol 9 (2006) 210-218
3. Mishra A., Hogan S.P., Brandt E.B., et al. Peyer's patch eosinophils: identification, characterization, and regulation by mucosal allergen exposure, interleukin-5, and eotaxin. Blood 96 (2000) 1538-1544
4. Rothenberg M.E. Eosinophilic gastrointestinal disorders (EGID). J Allergy Clin Immunol 113 (2004) 11-28
5. Rothenberg M.E., Mishra A., Brandt E.B., et al. Gastrointestinal eosinophils. Immunol Rev 179 (2001) 139-155
6. Rothenberg M.E., Mishra A., Brandt E.B., et al. Gastrointestinal eosinophils in health and disease. Adv Immunol 78 (2001) 291-328
7. Mishra A., Hogan S.P., Lee J.J., et al. Fundamental signals that regulate eosinophil homing to the gastrointestinal tract. J Clin Invest 103 (1999) 1719-1727
8. Rothenberg M.E., Luster A.D., Lilly C.M., et al. Constitutive and allergen-induced expression of eotaxin mRNA in the guinea pig lung. J Exp Med 181 (1995) 1211-1216
9. Garcia-Zepeda E.A., Combadiere C., Rothenberg M.E., et al. Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3. J Immunol 157 (1996) 5613-5626
10. Zimmermann N., Hogan S.P., Mishra A., et al. Murine eotaxin-2: a constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression. J Immunol 165 (2000) 5839-5846
11. Kitaura M., Suzuki N., Imai T., et al. Molecular cloning of a novel human CC chemokine (eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J Biolumin Chemilumin 274 (1999) 27975-27980
12. Matthews A.N., Friend D.S., Zimmermann N., et al. Eotaxin is required for the baseline level of tissue eosinophils. Proc Natl Acad Sci U S A 95 (1998) 6273-6278
13. Gurish M.F., Humbles A., Tao H., et al. CCR3 is required for tissue eosinophilia and larval cytotoxicity after infection with Trichinella spiralis. J Immunol 168 (2002) 5730-5736
14. Humbles A.A., Lu B., Friend D.S., et al. The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness. Proc Natl Acad Sci U S A 99 (2002) 1479-1484
15. Straumann A., Kristl J., Conus S., et al. Cytokine expression in healthy and inflamed mucosa: probing the role of eosinophils in the digestive tract. Inflamm Bowel Dis 11 (2005) 720-726
16. Blanchard C., Mingler M.K., Vicario M., et al. IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids. J Allergy Clin Immunol 120 (2007) 1292-1300
17. Mishra A., Hogan S.P., Brandt E.B., et al. IL-5 promotes eosinophil trafficking to the esophagus. J Immunol 168 (2002) 2464-2469
18. Mishra A., and Rothenberg M.E. Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT6-dependent mechanism. Gastroenterology 125 (2003) 1419-1427
19. Blanchard C., Wang N., Stringer K.F., et al. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J Clin Invest 116 (2006) 536-547
20. Blanchard C., Wang N., and Rothenberg M.E. Eosinophilic esophagitis: pathogenesis, genetics, and therapy. J Allergy Clin Immunol 118 (2006) 1054-1059
21. Blanchard C., Mingler M.K., MacBride M., et al. Periostin facilitates eosinophil tissue infiltration in allergic lung and esophageal responses. Mucosal Immunology 1 (2008) 289-296
22. Jaffe J.S., James S.P., Mullins G.E., et al. Evidence for an abnormal profile of interleukin-4 (IL-4), IL-5, and gamma-interferon (gamma-IFN) in peripheral blood T cells from patients with allergic eosinophilic gastroenteritis. J Clin Immunol 14 (1994) 299-309
23. Beyer K., Castro R., Birnbaum A., et al. Human milk-specific mucosal lymphocytes of the gastrointestinal tract display a TH2 cytokine profile. J Allergy Clin Immunol 109 (2002) 707-713
24. Katz A.J., Twarog F.J., Zeiger R.S., et al. Milk-sensitive and eosinophilic gastroenteropathy: similar clinical features with contrasting mechanisms and clinical course. J Allergy Clin Immunol 74 (1984) 72-78
25. Brandt E.B., Strait R.T., Hershko D., et al. Mast cells are required for experimental oral allergen-induced diarrhea. J Clin Invest 112 (2003) 1666-1677
26. Lee J.B., Matsumoto T., Shin Y.O., et al. The role of RANTES in a murine model of food allergy. Immunol Invest 33 (2004) 27-38
27. Yamada H., Izutani R., Chihara J., et al. RANTES mRNA expression in skin and colon of patients with atopic dermatitis. Int Arch Allergy Immunol 111 Suppl 1 (1996) 19-21
28. Ajuebor M.N., Hogaboam C.M., Kunkel S.L., et al. The chemokine RANTES is a crucial mediator of the progression from acute to chronic colitis in the rat. J Immunol 166 (2001) 552-558
29. Kweon M.N., Yamamoto M., Kajiki M., et al. Systemically derived large intestinal CD4(+) Th2 cells play a central role in STAT6-mediated allergic diarrhea. J Clin Invest 106 (2000) 199-206
30. Hogan S.P., Mishra A., Brandt E.B., et al. A critical role for eotaxin in experimental oral antigen-induced eosinophilic gastrointestinal allergy. Proc Natl Acad Sci USA 97 (2000) 6681-6686
31. Forbes E., Murase T., Yang M., et al. Immunopathogenesis of experimental ulcerative colitis is mediated by eosinophil peroxidase. J Immunol 172 (2004) 5664-5675
32. Pope S.M., Fulkerson P.C., Blanchard C., et al. Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation. J Biol Chem 280 (2005) 13952-13961
33. Wagsater D., Lofgren S., Hugander A., et al. Analysis of single nucleotide polymorphism in the promoter and protein expression of the chemokine eotaxin-1 in colorectal cancer patients. World J Surg Oncol 5 (2007) 84
34. Mazzucchelli L., Hauser C., Zgraggen K., et al. Differential in situ expression of the genes encoding the chemokines MCP-1 and RANTES in human inflammatory bowel disease. J Pathol 178 (1996) 201-206
35. Forbes E., Hulett M., Ahrens R., et al. ICAM-1-dependent pathways regulate colonic eosinophilic inflammation. J Leukoc Biol 80 (2006) 330-341
36. Mishra A., Hogan S.P., Brandt E.B., et al. Enterocyte expression of the eotaxin and interleukin-5 transgenes induces compartmentalized dysregulation of eosinophil trafficking. J Biol Chem 277 (2002) 4406-4412
37. Brandt E.B., Zimmermann N., Muntel E.E., et al. The alpha4bbeta7-integrin is dynamically expressed on murine eosinophils and involved in eosinophil trafficking to the intestine. Clin Exp Allergy 36 (2006) 543-553
38. Quack I., Sellin L., Buchner N.J., et al. Eosinophilic gastroenteritis in a young girl: long term remission under Montelukast. BMC Gastroenterol 5 (2005) 24
39. Attwood S.E., Lewis C.J., Bronder C.S., et al. Eosinophilic oesophagitis: a novel treatment using Montelukast. Gut 52 (2003) 181-185
40. Daikh B.E., Ryan C.K., and Schwartz R.H. Montelukast reduces peripheral blood eosinophilia but not tissue eosinophilia or symptoms in a patient with eosinophilic gastroenteritis and esophageal stricture. Ann Allergy Asthma Immunol 90 (2003) 23-27
41. Gupta S.K., Peters-Golden M., Fitzgerald J.F., et al. Cysteinyl leukotriene levels in esophageal mucosal biopsies of children with eosinophilic inflammation: are they all the same?. Am J Gastroenterol 101 (2006) 1125-1128
42. Urek M.C., Kujundzic M., Banic M., et al. Leukotriene receptor antagonists as potential steroid sparing agents in a patient with serosal eosinophilic gastroenteritis. Gut 55 (2006) 1363-1364
43. Garrett J.K., Jameson S.C., Thomson B., et al. Anti-interleukin-5 (mepolizumab) therapy for hypereosinophilic syndromes. J Allergy Clin Immunol 113 (2004) 115-119
44. Sutton S.A., Assa'ad A.H., and Rothenberg M.E. Anti-IL-5 and hypereosinophilic syndromes. Clin Immunol 115 (2005) 51-60
45. Stein M.L., Collins M.H., Villanueva J.M., et al. Anti-IL-5 (mepolizumab) therapy for eosinophilic esophagitis. J Allergy Clin Immunol 118 (2006) 1312-1319
46. Simon D., Braathen L.R., and Simon H.U. [Anti-interlekuin-5 therapy for eosinophilic diseases.]. Hautarzt 58 (2007) 122 124-7 [in German]