Substance P (SP) enhances CCL5-induced chemotaxis and intracellular signaling in human monocytes, which express the truncated neurokinin-1 receptor (NK1R)

Journal of Leukocyte Biology

Volumn 85, Issue 1, 2009, Pages 154-164

  Chernova, Irene ^a   Lai, Jian Ping ^a   Li, Haiying ^a   Schwartz, Lynnae ^b   Tuluc, Florin ^a   Korchak, Helen M ^a   Douglas, Steven D ^a   Kilpatrick, Laurie E ^a,c  

^a Department of Pediatrics   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Calcium mobilization; Chemokines; MAPKs; Phosphorylation; Receptor

Indexed keywords

CHEMOKINE RECEPTOR CCR5; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROKININ 1 RECEPTOR; RANTES; SUBSTANCE P;

ARTICLE; BLOOD; CHEMOTAXIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; INFLAMMATION; LEUKOCYTE; MACROPHAGE FUNCTION; MOBILIZATION; MONOCYTE; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TERMINAL SEQUENCE; VIRUS STRAIN;

CALCIUM; CATIONS, DIVALENT; CELLS, CULTURED; CHEMOKINE CCL5; CHEMOTAXIS, LEUKOCYTE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MONOCYTES; PHOSPHORYLATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CCR5; RECEPTORS, NEUROKININ-1; SIGNAL TRANSDUCTION; SUBSTANCE P;

EID: 58149252138     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0408260     Document Type: Article

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